Pedro Borralho
Pedro Borralho
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon
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Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
AL Sarver, AJ French, PM Borralho, V Thayanithy, AL Oberg, ...
BMC cancer 9 (1), 1-15, 2009
Delivering the promise of miRNA cancer therapeutics
DM Pereira, PM Rodrigues, PM Borralho, CMP Rodrigues
Drug discovery today 18 (5-6), 282-289, 2013
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease
RE Castro, DMS Ferreira, MB Afonso, PM Borralho, MV Machado, ...
Journal of hepatology 58 (1), 119-125, 2013
MicroRNA‐143 reduces viability and increases sensitivity to 5‐fluorouracil in HCT116 human colorectal cancer cells
PM Borralho, BT Kren, RE Castro, IB Moreira da Silva, CJ Steer, ...
The FEBS journal 276 (22), 6689-6700, 2009
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer
AL Oberg, AJ French, AL Sarver, S Subramanian, BW Morlan, SM Riska, ...
PloS one 6 (6), e20465, 2011
miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation
PM Borralho, AES Simões, SE Gomes, RT Lima, T Carvalho, ...
PloS one 6 (8), e23787, 2011
Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis
MB Afonso, PM Rodrigues, T Carvalho, M Caridade, P Borralho, ...
Clinical Science 129 (8), 721-739, 2015
Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid
RE Castro, DMS Ferreira, X Zhang, PM Borralho, AL Sarver, Y Zeng, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (4 …, 2010
Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF‐β1–induced apoptosis in rat hepatocytes
S Solá, JD Amaral, RE Castro, RM Ramalho, PM Borralho, BT Kren, ...
Hepatology 42 (4), 925-934, 2005
Cobalt complexes bearing scorpionate ligands: synthesis, characterization, cytotoxicity and DNA cleavage
TFS Silva, LM Martins, MFCG da Silva, AR Fernandes, A Silva, ...
Dalton transactions 41 (41), 12888-12897, 2012
Efficient recovery of proteins from multiple source samples after trizol® or trizol®LS RNA extraction and long-term storage
AES Simões, DM Pereira, JD Amaral, AF Nunes, SE Gomes, ...
BMC genomics 14 (1), 181, 2013
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver
DMS Ferreira, MB Afonso, PM Rodrigues, AL Simão, DM Pereira, ...
Molecular and cellular biology 34 (6), 1100-1120, 2014
NF‐κB and apoptosis in colorectal tumourigenesis
MM Aranha, PM Borralho, P Ravasco, IB Moreira da Silva, L Correia, ...
European journal of clinical investigation 37 (5), 416-424, 2007
Tauroursodeoxycholic acid modulates p53‐mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells
RM Ramalho, PM Borralho, RE Castro, S Solá, CJ Steer, CMP Rodrigues
Journal of neurochemistry 98 (5), 1610-1618, 2006
Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53
PM Borralho, IBM da Silva, MM Aranha, C Albuquerque, CN Leitão, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (1), 40-47, 2007
KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines
J Lavrado, H Brito, PM Borralho, SA Ohnmacht, NS Kim, C Leitão, S Pisco, ...
Scientific reports 5, 9696, 2015
Cyclopentadienyl–ruthenium (II) and iron (II) organometallic compounds with carbohydrate derivative ligands as good colorectal anticancer agents
PR Florindo, DM Pereira, PM Borralho, CMP Rodrigues, MFM Piedade, ...
Journal of medicinal chemistry 58 (10), 4339-4347, 2015
miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice
PM Rodrigues, MB Afonso, AL Simão, CC Carvalho, A Trindade, A Duarte, ...
Cell death & disease 8 (4), e2748-e2748, 2017
The MEK5/ERK5 signalling pathway in cancer: a promising novel therapeutic target
AES Simoes, CMP Rodrigues, PM Borralho
Drug discovery today 21 (10), 1654-1663, 2016
Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid β-peptide-induced apoptosis
S Sola, JD Amaral, PM Borralho, RM Ramalho, RE Castro, MM Aranha, ...
Molecular endocrinology 20 (10), 2292-2303, 2006
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