Gareth G Lavery
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11β-Hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response
JW Tomlinson, EA Walker, IJ Bujalska, N Draper, GG Lavery, MS Cooper, ...
Endocrine reviews 25 (5), 831-866, 2004
Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass …
N Krone, BA Hughes, GG Lavery, PM Stewart, W Arlt, CHL Shackleton
The Journal of steroid biochemistry and molecular biology 121 (3-5), 496-504, 2010
Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency
N Draper, EA Walker, IJ Bujalska, JW Tomlinson, SM Chalder, W Arlt, ...
Nature genetics 34 (4), 434-439, 2003
Hexose-6-phosphate dehydrogenase knock-out mice lack 11β-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation
GG Lavery, EA Walker, N Draper, P Jeyasuria, J Marcos, CHL Shackleton, ...
Journal of Biological Chemistry 281 (10), 6546-6551, 2006
11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess
SA Morgan, EL McCabe, LL Gathercole, ZK Hassan-Smith, DP Larner, ...
Proceedings of the National Academy of Sciences 111 (24), E2482-E2491, 2014
Targeted disruption of β-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex
AC Kim, AL Reuter, M Zubair, T Else, K Serecky, NC Bingham, GG Lavery, ...
Oxford University Press for The Company of Biologists Limited 135 (15), 2593 …, 2008
Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy
N Diguet, SAJ Trammell, C Tannous, R Deloux, J Piquereau, N Mougenot, ...
Circulation 137 (21), 2256-2273, 2018
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ...
Cell reports 28 (7), 1717-1728. e6, 2019
11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle
SA Morgan, M Sherlock, LL Gathercole, GG Lavery, C Lenaghan, ...
Diabetes 58 (11), 2506-2515, 2009
11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects
LL Gathercole, GG Lavery, SA Morgan, MS Cooper, AJ Sinclair, ...
Endocrine reviews 34 (4), 525-555, 2013
CA-Repeat polymorphism in intron 1 of HSD11B2: effects on gene expression and salt sensitivity
AK Agarwal, G Giacchetti, G Lavery, H Nikkila, M Palermo, M Ricketts, ...
Hypertension 36 (2), 187-194, 2000
Premature adrenarche: novel lessons from early onset androgen excess
J Idkowiak, GG Lavery, V Dhir, TG Barrett, PM Stewart, N Krone, W Arlt
European Journal of Endocrinology 165 (2), 189, 2011
11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects
A Tiganescu, AA Tahrani, SA Morgan, M Otranto, A Desmoulière, ...
The Journal of clinical investigation 123 (7), 3051-3060, 2013
Prereceptor regulation of glucocorticoid action by 11β‐hydroxysteroid dehydrogenase: a novel determinant of cell proliferation
EH Rabbitt, GG Lavery, EA Walker, MS Cooper, PM Stewart, M Hewison
The FASEB journal 16 (1), 36-44, 2002
Association studies between microsatellite markers within the gene encoding human 11β-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and …
N Draper, SM Echwald, GG Lavery, EA Walker, R Fraser, E Davies, ...
The Journal of Clinical Endocrinology & Metabolism 87 (11), 4984-4990, 2002
Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency
GG Lavery, EA Walker, A Tiganescu, JP Ride, CHL Shackleton, ...
The Journal of Clinical Endocrinology & Metabolism 93 (10), 3827-3832, 2008
Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy
GG Lavery, EA Walker, N Turan, D Rogoff, JW Ryder, JM Shelton, ...
Journal of Biological Chemistry 283 (13), 8453-8461, 2008
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
RS Fletcher, J Ratajczak, CL Doig, LA Oakey, R Callingham, GDS Xavier, ...
Molecular metabolism 6 (8), 819-832, 2017
Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice
JK Dowman, LJ Hopkins, GM Reynolds, MJ Armstrong, M Nasiri, ...
Endocrinology 154 (12), 4536-4547, 2013
Targeting NAD+ in metabolic disease: New insights into an old molecule
YS Elhassan, AA Philp, GG Lavery
Journal of the Endocrine Society 1 (7), 816-835, 2017
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