| Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 712 | 2021 |
| Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 489 | 2018 |
| Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs MGP Van Der Wijst, H Brugge, DH De Vries, P Deelen, MA Swertz, ... Nature genetics 50 (4), 493-497, 2018 | 313 | 2018 |
| Improving the diagnostic yield of exome-sequencing by predicting gene–phenotype associations using large-scale gene expression analysis P Deelen, S van Dam, JC Herkert, JM Karjalainen, H Brugge, KM Abbott, ... Nature communications 10 (1), 2837, 2019 | 120 | 2019 |
| An integrative approach for building personalized gene regulatory networks for precision medicine MGP Van Der Wijst, DH de Vries, H Brugge, HJ Westra, L Franke Genome medicine 10, 1-15, 2018 | 83 | 2018 |
| Deconvolution of bulk blood eQTL effects into immune cell subpopulations R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ... BMC bioinformatics 21, 1-23, 2020 | 47 | 2020 |
| Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure R Oelen, DH de Vries, H Brugge, MG Gordon, M Vochteloo, ... Nature communications 13 (1), 3267, 2022 | 36 | 2022 |
| Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease A Bangma, MD Voskuil, WTC Uniken Venema, H Brugge, S Hu, P Lanting, ... Alimentary Pharmacology & Therapeutics 51 (11), 1105-1115, 2020 | 27 | 2020 |
| Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response DH de Vries, V Matzaraki, OB Bakker, H Brugge, HJ Westra, MG Netea, ... PLoS pathogens 16 (4), e1008408, 2020 | 23 | 2020 |
| Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis. bioRxiv. 2018 U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Preprint at https://www. biorx iv. org/conte nt/10 1101, 44736, 0 | 18 | |
| Life Lines Cohort S. et al.(2018) MGP van der Wijst, H Brugge, DH de Vries, P Deelen, MA Swertz Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co …, 0 | 9 | |
| Single-cell RNA-sequencing reveals widespread personalized, context-specific gene expression regulation in immune cells R Oelen, DH de Vries, H Brugge, G Gordon, M Vochteloo, ... bioRxiv, 2021.06. 04.447088, 2021 | 6 | 2021 |
| Gene: PARK7 KY Ma, DH de Vries, H Brugge, MR Fokkens, L Wagenaar, L Franke Molecular genetics of monogenic movement disorders: making meaning of rare …, 2022 | | 2022 |
| An integrative approach for creating personalized gene regulatory networks for precision medicine MGP van der Wijst, DH de Vries, H Brugge, HJ Westra, L Franke Context matters, 17, 2022 | | 2022 |
| Improving diagnostic yield of exome-sequencing through prioritization of genes with predicted HPO assignments P Deelen, S van Dam, JM Karjalainen, H Brugge, P Folkertsma, ... European Journal of Human Genetics 27, 537-537, 2019 | | 2019 |
| Personalized co-expression networks reveal genetic risk factors that change the regulatory wiring of cells MGP van der Wijst, DH de Vries, H Brugge, P Deelen, MA Swertz, ... EUROPEAN JOURNAL OF HUMAN GENETICS 27, 789-790, 2019 | | 2019 |
