Rob Vreeken
Rob Vreeken
Associate Professor at M4I & Head Discovery & Exploratory BioAnalysis at Janssen R&D
Geverifieerd e-mailadres voor its.jnj.com
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Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients [S]
M Janssens, J van Smeden, GS Gooris, W Bras, G Portale, PJ Caspers, ...
Journal of lipid research 53 (12), 2755-2766, 2012
3732012
LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery [S]
J van Smeden, L Hoppel, R van der Heijden, T Hankemeier, RJ Vreeken, ...
Journal of lipid research 52 (6), 1211-1221, 2011
2292011
Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery
K Strassburg, AML Huijbrechts, KA Kortekaas, JH Lindeman, ...
Analytical and bioanalytical chemistry 404 (5), 1413-1426, 2012
2072012
Comprehensive LC−MSE Lipidomic Analysis using a Shotgun Approach and Its Application to Biomarker Detection and Identification in Osteoarthritis Patients
JM Castro-Perez, J Kamphorst, J DeGroot, F Lafeber, J Goshawk, K Yu, ...
Journal of proteome research 9 (5), 2377-2389, 2010
2012010
The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients
J van Smeden, M Janssens, ECJ Kaye, PJ Caspers, AP Lavrijsen, ...
Experimental dermatology 23 (1), 45-52, 2014
1962014
Selective analysis of the herbicides glyphosate and aminomethylphosphonic acid in water by on-line solid-phase extraction–high-performance liquid chromatography–electrospray …
RJ Vreeken, P Speksnijder, I Bobeldijk-Pastorova, THM Noij
Journal of chromatography A 794 (1-2), 187-199, 1998
1821998
Lipidomics of familial longevity
V Gonzalez‐Covarrubias, M Beekman, HW Uh, A Dane, J Troost, ...
Aging cell 12 (3), 426-434, 2013
1442013
Determination of polar organophosphorus pesticides in aqueous samples by direct injection using liquid chromatography–tandem mass spectrometry
BA Ingelse, RCJ Van Dam, RJ Vreeken, HGJ Mol, OM Steijger
Journal of Chromatography A 918 (1), 67-78, 2001
1442001
Lamellar lipid organization and ceramide composition in the stratum corneum of patients with atopic eczema
M Janssens, J van Smeden, GS Gooris, W Bras, G Portale
Journal of investigative dermatology 131 (10), 2136-2138, 2011
1382011
Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis
MJ Noga, A Dane, S Shi, A Attali, H van Aken, E Suidgeest, T Tuinstra, ...
Metabolomics 8 (2), 253-263, 2012
1262012
Recent developments in sample-pretreatment techniques for mass spectrometry-based metabolomics
RJ Raterink, PW Lindenburg, RJ Vreeken, R Ramautar, T Hankemeier
TrAC Trends in Analytical Chemistry 61, 157-167, 2014
1162014
Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry
J Castro-Perez, TP Roddy, NMM Nibbering, V Shah, DG McLaren, ...
Journal of the American Society for Mass Spectrometry 22 (9), 1552-1567, 2011
1142011
The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF)
T Rosenling, CL Slim, C Christin, L Coulier, S Shi, MP Stoop, J Bosman, ...
Journal of proteome research 8 (12), 5511-5522, 2009
1142009
Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes
J van Smeden, WA Boiten, T Hankemeier, R Rissmann, JA Bouwstra, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014
1052014
Mass spectrometric analysis of intact human monoclonal antibody aggregates fractionated by size-exclusion chromatography
B Kükrer, V Filipe, E van Duijn, PT Kasper, RJ Vreeken, AJR Heck, ...
Pharmaceutical research 27 (10), 2197-2204, 2010
1032010
Metabolite identification using automated comparison of high-resolution multistage mass spectral trees
M Rojas-Cherto, JE Peironcely, PT Kasper, JJJ van der Hooft, ...
Analytical chemistry 84 (13), 5524-5534, 2012
962012
Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection [S]
CWN Damen, G Isaac, J Langridge, T Hankemeier, RJ Vreeken
Journal of lipid research 55 (8), 1772-1783, 2014
932014
A branched biosynthetic pathway is involved in production of roquefortine and related compounds in Penicillium chrysogenum
H Ali, MI Ries, JG Nijland, PP Lankhorst, T Hankemeier, RAL Bovenberg, ...
PloS one 8 (6), e65328, 2013
892013
Intercellular skin barrier lipid composition and organization in Netherton syndrome patients
J Van Smeden, M Janssens, WA Boiten, V Van Drongelen, L Furio, ...
Journal of Investigative Dermatology 134 (5), 1238-1245, 2014
872014
An efficient hydrophilic interaction liquid chromatography separation of 7 phospholipid classes based on a diol column
C Zhu, A Dane, G Spijksma, M Wang, J Van der Greef, G Luo, ...
Journal of Chromatography A 1220, 26-34, 2012
852012
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Artikelen 1–20