A comparative evaluation of models to predict human intestinal metabolism from nonclinical data E Yau, C Petersson, H Dolgos, SA Peters Biopharmaceutics & drug disposition 38 (3), 163-186, 2017 | 31 | 2017 |
Global sensitivity analysis of the Rodgers and Rowland model for prediction of tissue: plasma partitioning coefficients: assessment of the key physiological and physicochemical … E Yau, A Olivares-Morales, M Gertz, N Parrott, AS Darwich, L Aarons, ... The AAPS journal 22, 1-13, 2020 | 18 | 2020 |
Investigation of simplified physiologically‐based pharmacokinetic models in rat and human E Yau, A Olivares‐Morales, K Ogungbenro, L Aarons, M Gertz CPT: Pharmacometrics & Systems Pharmacology 12 (3), 333-345, 2023 | 3 | 2023 |
A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models E Yau, M Gertz, K Ogungbenro, L Aarons, A Olivares‐Morales CPT: Pharmacometrics & Systems Pharmacology 12 (3), 346-359, 2023 | 3 | 2023 |
A systematic framework to integrate preclinical data within PBPK models: from global sensitivity analysis to middle-out approaches E Yau PQDT-UK & Ireland, 2021 | | 2021 |
Physiologically-based pharmacokinetic (PBPK) models for translation of drug distribution from rat to human E Yau, M Gertz, L Aarons, K Ogungbenro, A Olivares-Morales | | |