A landscape of circular RNA expression in the human heart. WLW Tan, BTS Lim, CGO Anene-Nzelu, M Ackers-Johnson, A Dashi, ... Cardiovascular Research, 2017 | 267 | 2017 |
Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression AC Cardoso, NT Lam, JJ Savla, Y Nakada, AHM Pereira, A Elnwasany, ... Nature metabolism 2 (2), 167-178, 2020 | 158 | 2020 |
Large-scale whole-genome sequencing of three diverse Asian populations in Singapore D Wu, J Dou, X Chai, C Bellis, A Wilm, CC Shih, WWJ Soon, N Bertin, ... Cell 179 (3), 736-749. e15, 2019 | 146 | 2019 |
Extracellular vesicles from human embryonic stem cell-derived cardiovascular progenitor cells promote cardiac infarct healing through reducing cardiomyocyte death and promoting … Q Wu, J Wang, WLW Tan, Y Jiang, S Wang, Q Li, X Yu, J Tan, S Liu, ... Cell death & disease 11 (5), 354, 2020 | 114 | 2020 |
A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes NUN Nguyen, DC Canseco, F Xiao, Y Nakada, S Li, NT Lam, ... Nature 582 (7811), 271-276, 2020 | 95 | 2020 |
Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo K See, WLW Tan, EH Lim, Z Tiang, LT Lee, PYQ Li, TDA Luu, ... Nature communications 8 (1), 225, 2017 | 95 | 2017 |
Adipose circular RNAs exhibit dynamic regulation in obesity and functional role in adipogenesis C Arcinas, W Tan, W Fang, TP Desai, DCS Teh, U Degirmenci, D Xu, ... Nature metabolism 1 (7), 688-703, 2019 | 71 | 2019 |
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function JS Hawe, R Wilson, KT Schmid, L Zhou, LN Lakshmanan, BC Lehne, ... Nature genetics 54 (1), 18-29, 2022 | 65 | 2022 |
Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescence W Xu, G Monaco, EH Wong, WLW Tan, H Kared, Y Simoni, SW Tan, ... EBioMedicine 39, 44-58, 2019 | 58 | 2019 |
A circular RNA derived from the insulin receptor locus protects against doxorubicin-induced cardiotoxicity D Lu, S Chatterjee, K Xiao, I Riedel, CK Huang, A Costa, S Cushman, ... European Heart Journal 43 (42), 4496-4511, 2022 | 51 | 2022 |
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer SY Loo, LP Toh, WH Xie, E Pathak, W Tan, S Ma, MY Lee, ... Science Advances 7 (41), eabh2443, 2021 | 50 | 2021 |
Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease M Ackers-Johnson, WLW Tan, RSY Foo Nature Communications 9 (1), 4434, 2018 | 49 | 2018 |
An important role for DNMT3A-mediated DNA methylation in cardiomyocyte metabolism and contractility A Madsen, G Höppner, J Krause, MN Hirt, SD Laufer, M Schweizer, ... Circulation 142 (16), 1562-1578, 2020 | 46 | 2020 |
Robust CTCF-based chromatin architecture underpins epigenetic changes in the heart failure stress–gene response DP Lee, WLW Tan, CG Anene-Nzelu, CJM Lee, PY Li, TDA Luu, CX Chan, ... Circulation 139 (16), 1937-1956, 2019 | 46 | 2019 |
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats J Stenzig, Y Schneeberger, A Löser, BS Peters, A Schaefer, RR Zhao, ... Journal of Molecular and Cellular Cardiology 120, 53-63, 2018 | 46 | 2018 |
Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf CY Tan, JX Wong, PS Chan, H Tan, D Liao, W Chen, LW Tan, ... Circulation research 125 (9), 834-846, 2019 | 43 | 2019 |
A Transcriptomic and Epigenomic Comparison of Fetal and Adult Human Cardiac Fibroblasts Reveals Novel Key Transcription Factors in Adult Cardiac Fibroblasts MKB Jonsson, RJG Hartman, M Ackers-Johnson, WLW Tan, B Lim, ... JACC: Basic to Translational Science 1 (7), 590-602, 2016 | 41 | 2016 |
[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial X Wu, R Senanayake, E Goodchild, WA Bashari, J Salsbury, CP Cabrera, ... Nature Medicine 29 (1), 190-202, 2023 | 37 | 2023 |
Persistent changes in liver methylation and microbiome composition following reversal of diet-induced non-alcoholic-fatty liver disease H Kim, O Worsley, E Yang, RW Purbojati, AL Liang, W Tan, DID Moses, ... Cellular and molecular life sciences 76, 4341-4354, 2019 | 36 | 2019 |
Incidentalome from genomic sequencing: a barrier to personalized medicine? SS Jamuar, JL Kuan, M Brett, Z Tiang, WLW Tan, JY Lim, WKM Liew, ... EBioMedicine 5, 211-216, 2016 | 31 | 2016 |