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Prof. Dr. Steven Verhelst
Prof. Dr. Steven Verhelst
University of Leuven, Belgium & Leibniz Institute ISAS, Germany
Geverifieerd e-mailadres voor kuleuven.be - Homepage
Titel
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Jaar
Tagging and detection strategies for activity-based proteomics
AM Sadaghiani, SHL Verhelst, M Bogyo
Current opinion in chemical biology 11 (1), 20-28, 2007
3152007
Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages
GP Shi, RAR Bryant, R Riese, S Verhelst, C Driessen, Z Li, D Bromme, ...
The Journal of experimental medicine 191 (7), 1177-1186, 2000
3062000
Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs
M Bogyo, S Verhelst, V Bellingard-Dubouchaud, S Toba, D Greenbaum
Chemistry & biology 7 (1), 27-38, 2000
2812000
ATP13A2 deficiency disrupts lysosomal polyamine export
S van Veen, S Martin, C Van den Haute, V Benoy, J Lyons, R Vanhoutte, ...
Nature 578 (7795), 419-424, 2020
2482020
A mild chemically cleavable linker system for functional proteomic applications
SHL Verhelst, M Fonovic, M Bogyo
Angew. Chem. Int. Ed 46 (8), 1284-1286, 2007
1862007
Activity‐based probes for the study of proteases: recent advances and developments
S Serim, U Haedke, SHL Verhelst
ChemMedChem 7 (7), 1146-1159, 2012
1292012
Proteomics evaluation of chemically cleavable activity-based probes
M Fonovic, SHL Verhelst, MT Sorum, M Bogyo
Molecular & Cellular Proteomics 6 (10), 1761-1770, 2007
1182007
The structural basis for catalysis and substrate specificity of a rhomboid protease
KR Vinothkumar, K Strisovsky, A Andreeva, Y Christova, S Verhelst, ...
The EMBO journal 29 (22), 3797-3809, 2010
1152010
Proteome-wide detection of S-nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique
R Mnatsakanyan, S Markoutsa, K Walbrunn, A Roos, SHL Verhelst, ...
Nature communications 10 (1), 2195, 2019
992019
Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases
AM Sadaghiani, SHL Verhelst, V Gocheva, K Hill, E Majerova, S Stinson, ...
Chemistry & biology 14 (5), 499-511, 2007
902007
Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase
F Schlauderer, K Lammens, D Nagel, M Vincendeau, AC Eitelhuber, ...
Angewandte Chemie International Edition 52 (39), 10384-10387, 2013
832013
A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C
F Yuan, SHL Verhelst, G Blum, LM Coussens, M Bogyo
Journal of the American Chemical Society 128 (17), 5616-5617, 2006
792006
A simple and effective cleavable linker for chemical proteomics applications
Y Yang, H Hahne, B Kuster, SHL Verhelst
Molecular & Cellular Proteomics 12 (1), 237-244, 2013
762013
Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using ‘click chemistry’
F Kaschani, SHL Verhelst, PF Van Swieten, M Verdoes, CS Wong, ...
The Plant Journal 57 (2), 373-385, 2009
752009
Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay
O Vosyka, KR Vinothkumar, EV Wolf, AJ Brouwer, RMJ Liskamp, ...
Proceedings of the National Academy of Sciences 110 (7), 2472-2477, 2013
742013
A Short route toward chiral, polyhydroxylated indolizidines and quinolizidines
SHL Verhelst, B Paez Martinez, MSM Timmer, G Lodder, ...
The Journal of Organic Chemistry 68 (25), 9598-9603, 2003
722003
A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile …
SA Beckham, D Piedrafita, CI Phillips, N Samarawickrema, RHP Law, ...
The international journal of biochemistry & cell biology 41 (7), 1601-1612, 2009
672009
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system
NN Hamouda, C Van den Haute, R Vanhoutte, R Sannerud, M Azfar, ...
Journal of Biological Chemistry 296, 2021
642021
Surface plasmon resonance evaluation of various aminoglycoside–RNA hairpin interactions reveals low degree of selectivity
SHL Verhelst, PJA Michiels, GA van der Marel, CAA van Boeckel, ...
ChemBioChem 5 (7), 937-942, 2004
592004
Development of calpain-specific inactivators by screening of positional scanning epoxide libraries
D Cuerrier, T Moldoveanu, RL Campbell, J Kelly, B Yoruk, SHL Verhelst, ...
Journal of Biological Chemistry 282 (13), 9600-9611, 2007
582007
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Artikelen 1–20