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Marian Beekman
Marian Beekman
Senior Scientist, Molecular Epidemiology, LUMC
Geverifieerd e-mailadres voor lumc.nl
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Jaar
Genetic studies of body mass index yield new insights for obesity biology
AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ...
Nature 518 (7538), 197-206, 2015
40242015
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173, 2014
19402014
New genetic loci link adipose and insulin biology to body fat distribution
D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ...
Nature 518 (7538), 187-196, 2015
13622015
Identification of seven loci affecting mean telomere length and their association with disease
V Codd, CP Nelson, E Albrecht, M Mangino, J Deelen, JL Buxton, ...
Nature genetics 45 (4), 422-427, 2013
8492013
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze, PC Tsai, JS Ried, ...
Nature 541 (7635), 81-86, 2017
7072017
Whole-genome sequence variation, population structure and demographic history of the Dutch population
Nature genetics 46 (8), 818-825, 2014
6552014
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ...
PLoS genetics 8 (3), e1002607, 2012
5102012
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
J Kettunen, A Demirkan, P Würtz, HHM Draisma, T Haller, R Rawal, ...
Nature communications 7 (1), 11122, 2016
5062016
Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
L Broer, V Codd, DR Nyholt, J Deelen, M Mangino, G Willemsen, ...
European journal of human genetics 21 (10), 1163-1168, 2013
4442013
Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study
M Schoenmaker, AJM de Craen, PHEM de Meijer, M Beekman, GJ Blauw, ...
European Journal of Human Genetics 14 (1), 79-84, 2006
4222006
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
3742017
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
3622017
Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
G Lauc, JE Huffman, M Pučić, L Zgaga, B Adamczyk, A Mužinić, ...
PLoS genetics 9 (1), e1003225, 2013
3582013
Reduced insulin/IGF‐1 signalling and human longevity
D Van Heemst, M Beekman, SP Mooijaart, BT Heijmans, BW Brandt, ...
Aging cell 4 (2), 79-85, 2005
3392005
The impact of low-frequency and rare variants on lipid levels
I Surakka, M Horikoshi, R Mägi, AP Sarin, A Mahajan, V Lagou, L Marullo, ...
Nature genetics 47 (6), 589-597, 2015
3252015
Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
J Deelen, M Beekman, HW Uh, Q Helmer, M Kuningas, L Christiansen, ...
Aging cell 10 (4), 686-698, 2011
3082011
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
X Jiang, PF O’Reilly, H Aschard, YH Hsu, JB Richards, J Dupuis, ...
Nature communications 9 (1), 260, 2018
2992018
The Genome of the Netherlands: design, and project goals
DI Boomsma, C Wijmenga, EP Slagboom, MA Swertz, LC Karssen, ...
European Journal of Human Genetics 22 (2), 221-227, 2014
2912014
Genetic and environmental influences interact with age and sex in shaping the human methylome
J Van Dongen, MG Nivard, G Willemsen, JJ Hottenga, Q Helmer, ...
Nature communications 7 (1), 11115, 2016
2902016
Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study
RGJ Westendorp, D Van Heemst, MP Rozing, M Frölich, SP Mooijaart, ...
Journal of the American Geriatrics Society 57 (9), 1634-1637, 2009
2882009
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Artikelen 1–20