Brent R. Stockwell
Brent R. Stockwell
Professor of Biological Sciences and Chemistry
Verified email at - Homepage
Cited by
Cited by
Ferroptosis: an iron-dependent form of nonapoptotic cell death
SJ Dixon, KM Lemberg, MR Lamprecht, R Skouta, EM Zaitsev, ...
cell 149 (5), 1060-1072, 2012
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
Regulation of ferroptotic cancer cell death by GPX4
WS Yang, R SriRamaratnam, ME Welsch, K Shimada, R Skouta, ...
Cell 156 (1), 317-331, 2014
Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease
BR Stockwell, JPF Angeli, H Bayir, AI Bush, M Conrad, SJ Dixon, S Fulda, ...
Cell 171 (2), 273-285, 2017
Ferroptosis: mechanisms, biology and role in disease
X Jiang, BR Stockwell, M Conrad
Nature reviews Molecular cell biology 22 (4), 266-282, 2021
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
JP Friedmann Angeli, M Schneider, B Proneth, YY Tyurina, VA Tyurin, ...
Nature cell biology 16 (12), 1180-1191, 2014
Ferroptosis: death by lipid peroxidation
WS Yang, BR Stockwell
Trends in cell biology 26 (3), 165-176, 2016
The role of iron and reactive oxygen species in cell death
SJ Dixon, BR Stockwell
Nature chemical biology 10 (1), 9-17, 2014
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ...
Cell 124 (6), 1283-1298, 2006
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
VE Kagan, G Mao, F Qu, JPF Angeli, S Doll, CS Croix, HH Dar, B Liu, ...
Nature chemical biology 13 (1), 81-90, 2017
Lipid peroxidation in cell death
MM Gaschler, BR Stockwell
Biochemical and biophysical research communications 482 (3), 419-425, 2017
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
WS Yang, KJ Kim, MM Gaschler, M Patel, MS Shchepinov, BR Stockwell
Proceedings of the National Academy of Sciences 113 (34), E4966-E4975, 2016
Privileged scaffolds for library design and drug discovery
ME Welsch, SA Snyder, BR Stockwell
Current opinion in chemical biology 14 (3), 347-361, 2010
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
SJ Dixon, DN Patel, M Welsch, R Skouta, ED Lee, M Hayano, AG Thomas, ...
elife 3, e02523, 2014
An induced proximity model for caspase-8 activation
M Muzio, BR Stockwell, HR Stennicke, GS Salvesen, VM Dixit
Journal of Biological Chemistry 273 (5), 2926-2930, 1998
Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
WS Yang, BR Stockwell
Chemistry & biology 15 (3), 234-245, 2008
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ...
Nature 547 (7664), 453-457, 2017
RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
N Yagoda, M Von Rechenberg, E Zaganjor, AJ Bauer, WS Yang, ...
Nature 447 (7146), 865-869, 2007
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
S Dolma, SL Lessnick, WC Hahn, BR Stockwell
Cancer cell 3 (3), 285-296, 2003
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