Brent R. Stockwell
Brent R. Stockwell
Professor of Biological Sciences and Chemistry
Adresse e-mail validée de columbia.edu - Page d'accueil
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
76732021
Ferroptosis: an iron-dependent form of nonapoptotic cell death
SJ Dixon, KM Lemberg, MR Lamprecht, R Skouta, EM Zaitsev, ...
Cell 149 (5), 1060-1072, 2012
32532012
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
20382018
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ...
Cell 124 (6), 1283-1298, 2006
17302006
Regulation of ferroptotic cancer cell death by GPX4
WS Yang, R SriRamaratnam, ME Welsch, K Shimada, R Skouta, ...
Cell 156 (1-2), 317-331, 2014
16382014
An induced proximity model for caspase-8 activation
M Muzio, BR Stockwell, HR Stennicke, GS Salvesen, VM Dixit
Journal of Biological Chemistry 273 (5), 2926-2930, 1998
14851998
Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease
BR Stockwell, JPF Angeli, H Bayir, AI Bush, M Conrad, SJ Dixon, S Fulda, ...
Cell 171 (2), 273-285, 2017
14672017
Privileged scaffolds for library design and drug discovery
ME Welsch, SA Snyder, BR Stockwell
Current opinion in chemical biology 14 (3), 347-361, 2010
12062010
The role of iron and reactive oxygen species in cell death
SJ Dixon, BR Stockwell
Nature chemical biology 10 (1), 9-17, 2014
10722014
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
JPF Angeli, M Schneider, B Proneth, YY Tyurina, VA Tyurin, VJ Hammond, ...
Nature cell biology 16 (12), 1180-1191, 2014
9912014
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L Galluzzi, JM Bravo-San Pedro, I Vitale, SA Aaronson, JM Abrams, ...
Cell Death & Differentiation 22 (1), 58-73, 2015
8332015
Ferroptosis: death by lipid peroxidation
WS Yang, BR Stockwell
Trends in cell biology 26 (3), 165-176, 2016
8222016
Multicomponent therapeutics for networked systems
CT Keith, AA Borisy, BR Stockwell
Nature reviews Drug discovery 4 (1), 71-78, 2005
7912005
Lipid peroxidation in cell death
MM Gaschler, BR Stockwell
Biochemical and biophysical research communications 482 (3), 419-425, 2017
6662017
RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
N Yagoda, M von Rechenberg, E Zaganjor, AJ Bauer, WS Yang, ...
Nature 447 (7146), 865-869, 2007
6592007
Conserved pathways within bacteria and yeast as revealed by global protein network alignment
BP Kelley, R Sharan, RM Karp, T Sittler, DE Root, BR Stockwell, T Ideker
Proceedings of the National Academy of Sciences 100 (20), 11394-11399, 2003
6542003
Systematic discovery of multicomponent therapeutics
AA Borisy, PJ Elliott, NW Hurst, MS Lee, J Lehár, ER Price, G Serbedzija, ...
Proceedings of the National Academy of Sciences 100 (13), 7977-7982, 2003
6542003
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
SJ Dixon, DN Patel, M Welsch, R Skouta, ED Lee, M Hayano, AG Thomas, ...
elife 3, e02523, 2014
6132014
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
VE Kagan, G Mao, F Qu, JPF Angeli, S Doll, C St Croix, HH Dar, B Liu, ...
Nature chemical biology 13 (1), 81-90, 2017
6122017
Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
WS Yang, BR Stockwell
Chemistry & biology 15 (3), 234-245, 2008
5862008
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