LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia Y Tarumoto, B Lu, TDD Somerville, YH Huang, JP Milazzo, XS Wu, ... Molecular cell 69 (6), 1017-1027. e6, 2018 | 130 | 2018 |
Tel1ATM and Rad3ATR phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast H Yamazaki, Y Tarumoto, F Ishikawa Genes & development 26 (3), 241-246, 2012 | 85 | 2012 |
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia Y Xu, JP Milazzo, TDD Somerville, Y Tarumoto, YH Huang, EL Ostrander, ... Cancer cell 33 (1), 13-28. e8, 2018 | 74 | 2018 |
A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence B Lu, O Klingbeil, Y Tarumoto, TDD Somerville, YH Huang, Y Wei, ... Cancer cell 34 (6), 970-981. e8, 2018 | 55 | 2018 |
Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo Y Tarumoto, S Lin, J Wang, JP Milazzo, Y Xu, B Lu, Z Yang, Y Wei, ... Blood, The Journal of the American Society of Hematology 135 (1), 56-70, 2020 | 48 | 2020 |
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia S Takao, L Forbes, M Uni, S Cheng, JMB Pineda, Y Tarumoto, P Cifani, ... Elife 10, e65905, 2021 | 37 | 2021 |
KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements YZ Au, M Gu, E De Braekeleer, M Gozdecka, D Aspris, Y Tarumoto, ... Leukemia 35 (4), 1012-1022, 2021 | 29 | 2021 |
Fission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres M Takikawa, Y Tarumoto, F Ishikawa Nucleic acids research 45 (3), 1255-1269, 2017 | 26 | 2017 |
Receptor for activated C-kinase (RACK1) homolog Cpc2 facilitates the general amino acid control response through Gcn2 kinase in fission yeast Y Tarumoto, J Kanoh, F Ishikawa Journal of Biological Chemistry 288 (26), 19260-19268, 2013 | 21 | 2013 |
HIRA, a conserved histone chaperone, plays an essential role in low-dose stress response via transcriptional stimulation in fission yeast M Chujo, Y Tarumoto, K Miyatake, E Nishida, F Ishikawa Journal of Biological Chemistry 287 (28), 23440-23450, 2012 | 16 | 2012 |
Tankyrase inhibition sensitizes cells to CDK4 blockade M Foronda, Y Tarumoto, EM Schatoff, BI Leach, BJ Diaz, J Zimmerman, ... PloS one 14 (12), e0226645, 2019 | 8 | 2019 |
Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast H Irie, I Yamamoto, Y Tarumoto, S Tashiro, KW Runge, F Ishikawa PLOS Genetics 15 (8), e1008335, 2019 | 5 | 2019 |
Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia K Aoki, M Hyuga, Y Tarumoto, G Nishibuchi, A Ueda, Y Ochi, S Sugino, ... Blood 143 (7), 604-618, 2024 | 1 | 2024 |
RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations M Ishikawa, S Sugino, Y Masuda, Y Tarumoto, Y Seto, N Taniyama, ... Communications Biology 6 (1), 1290, 2023 | 1 | 2023 |
Genome-scale CRISPR–Cas9 screen identifies novel host factors as potential therapeutic targets for SARS-CoV-2 infection. M Sakai, Y Masuda, Y Tarumoto, N Aihara, Y Tsunoda, M Iwata, Y Kamiya, ... bioRxiv, 2023.03. 06.531431, 2023 | | 2023 |
Targeting Salt-Inducible Kinase 3 As a Therapeutic Approach for Acute Myeloid Leukemia S Lin, Y Tarumoto, J Wang, J Milazzo, Y Xu, N Gray, C Vakoc, ... Blood 134, 3941, 2019 | | 2019 |
The Salt-Inducible Kinase inhibitor YKL-05-099 suppresses MEF2C function and acute myeloid leukemia progression in vivo Y Tarumoto, S Lin, J Wang, J Milazzo, Y Xu, N Gray, K Stegmaier, ... BioRxiv, 636969, 2019 | | 2019 |
Selection inhibition of acute myeloid leukemia by targeting Taf12 Y Xu, J Milazzo, Y Tarumoto, C Vakoc Cancer Research 77 (13_Supplement), 1510-1510, 2017 | | 2017 |