Bertram Klinger

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Nils BlüthgenCharité Universitätsmedizin Berlin - IRI Life SciencesVerified email at charite.de
Florian UhlitzMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org
Julio Saez RodriguezHeidelberg UniversityVerified email at bioquant.uni-heidelberg.de
Franziska WitzelCharité/ HU BerlinVerified email at charite.de
Michael SchubertPostdoc, Netherlands Cancer Institute (NKI-AVL)Verified email at nki.nl
Michael FählingProfessor for Molecular Physiology, Charité - Universitätsmedizin BerlinVerified email at charite.de
Ralf MrowkaProfessor at Friedrich-Schiller-University Jena, Faculty of MedicineVerified email at med.uni-jena.de
Federica EduatiTechnische Universiteit EindhovenVerified email at tue.nl
Thomas CokelaerInstitut PasteurVerified email at pasteur.fr
Yu (Brandon) XiaProfessor of Bioengineering, McGill UniversityVerified email at mcgill.ca
Hanspeter HerzelInstitute for Theoretical BiologyVerified email at biologie.hu-berlin.de
Markus LandthalerMax-Delbrück-Center for Molecular Medicine Berlin,IRI Life Sciences Humboldt-Universität zu BerlinVerified email at mdc-berlin.de
Emanuel WylerPostdoc, Berlin Institute for Medical Systems Biology, Max Delbruck Center for MolecularVerified email at mdc-berlin.de
Jonas J. StaudacherCharité - Universiätsmedizin Berlin - Division of Gastroenterology, Infectology and RheumatologyVerified email at charite.de
Pascal SchulthessHubrecht Institute, Utrecht, The NetherlandsVerified email at hubrecht.eu
Thorsten CramerMolecular Tumor Biology, RWTH University Hospital Aachen, GermanyVerified email at ukaachen.de
Philippe ThomasGerman Research Center for Artificial IntelligenceVerified email at dfki.de
Ulf LeserKnowledge Management in Bioinformatics, Humboldt-Universität zu BerlinVerified email at informatik.hu-berlin.de
Domonkos TikkGravity R&D, a Taboola companyVerified email at taboola.com
stefan kempaBIMSB@MDC Berlin-BuchVerified email at mdc-berlin.de

Bertram Klinger

Postdoc in Computational Modelling in Medicine, Charité Universitätsmedizin Berlin

Verified email at charite.de


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Perturbation-response genes reveal signaling footprints in cancer gene expression M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ... Nature Communications 9 (1), 11, 2018	315	2018
Network quantification of EGFR signaling unveils potential for targeted combination therapy B Klinger, A Sieber, R Fritsche‐Guenther, F Witzel, L Berry, ... Molecular systems biology 9 (1), 673, 2013	159	2013
Drug resistance mechanisms in colorectal cancer dissected with cell type–specific dynamic logic models F Eduati, V Doldàn-Martelli, B Klinger, T Cokelaer, A Sieber, F Kogera, ... Cancer research 77 (12), 3364-3375, 2017	95	2017
Discovering causal signaling pathways through gene-expression patterns JR Parikh, B Klinger, Y Xia, JA Marto, N Blï¿ ½thgen Nucleic acids research 38 (suppl_2), W109-W117, 2010	70	2010
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium R Brandt, T Sell, M Lüthen, F Uhlitz, B Klinger, P Riemer, ... Nature communications 10 (1), 1-15, 2019	58	2019
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS I Stelniec‐Klotz, S Legewie, O Tchernitsa, F Witzel, B Klinger, C Sers, ... Molecular systems biology 8 (1), 601, 2012	58	2012
The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells R Redmer, Walz, Klinger, Khouja, Welte, Schäfer Oncogenesis 6 (1), e291, 2017	57	2017
An immediate-late gene expression module decodes ERK signal duration F Uhlitz, A Sieber, E Wyler, R Fritsche‐Guenther, J Meisig, M Landthaler, ... Molecular Systems Biology 13 (5), 2017	56	2017
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum JJ Staudacher, IS Naarmann-de Vries, SJ Ujvari, B Klinger, M Kasim, ... Nucleic acids research 43 (6), 3219-3236, 2015	44	2015
Isoform-specific Ras signaling is growth factor dependent FE Hood, B Klinger, AU Newlaczyl, A Sieber, M Dorel, SP Oliver, ... Molecular biology of the cell 30 (9), 1108-1117, 2019	31	2019
Modelling signalling networks from perturbation data M Dorel, B Klinger, T Gross, A Sieber, A Prahallad, E Bosdriesz, ... Bioinformatics 34 (23), 4079-4086, 2018	30	2018
SPEED2: inferring upstream pathway activity from differential gene expression M Rydenfelt, B Klinger, M Klünemann, N Blüthgen Nucleic Acids Research, 2020	23	2020
SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells K Klotz-Noack, B Klinger, M Rivera, N Bublitz, F Uhlitz, P Riemer, ... Cell Reports 32 (12), 108184, 2020	18	2020
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A N Rohwer, F Bindel, C Grimm, SJ Lin, J Wappler, B Klinger, N Blüthgen, ... Oncotarget 7 (6), 6693, 2016	18	2016
Computer-assisted curation of a human regulatory core network from the biological literature P Thomas, P Durek, I Solt, B Klinger, F Witzel, P Schulthess, Y Mayer, ... Bioinformatics 31 (8), 1258-1266, 2015	18	2015
Consequences of feedback in signal transduction for targeted therapies B Klinger, N Blüthgen Biochemical Society Transactions 42 (4), 770-775, 2014	18	2014
Multilevel regulation of HIF-1 signaling by TTP M Fähling, AB Persson, B Klinger, E Benko, A Steege, M Kasim, A Patzak, ... Molecular biology of the cell 23 (20), 4129-4141, 2012	18	2012
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma U Schoetz, D Klein, J Hess, S Shnayien, S Spoerl, M Orth, S Mutlu, ... Cell death & disease 12 (12), 1-14, 2021	16	2021
Reverse engineering gene regulatory networks by modular response analysis–a benchmark B Klinger, N Bluethgen Essays In Biochemistry 62 (4), 535-547, 2018	13	2018
Comparative Network Reconstruction using mixed integer programming E Bosdriesz, A Prahallad, B Klinger, A Sieber, A Bosma, R Bernards, ... Bioinformatics 34 (17), i997-i1004, 2018	12	2018

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