Bertram Klinger
Bertram Klinger
Postdoc in Computational Modelling in Medicine, Charité Universitätsmedizin Berlin
Verified email at
Cited by
Cited by
Network quantification of EGFR signaling unveils potential for targeted combination therapy
B Klinger, A Sieber, R Fritsche‐Guenther, F Witzel, L Berry, ...
Molecular systems biology 9 (1), 2013
Perturbation-response genes reveal signaling footprints in cancer gene expression
M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ...
Nature Communications 9 (1), 11, 2018
Discovering causal signaling pathways through gene-expression patterns
JR Parikh, B Klinger, Y Xia, JA Marto, N Blï¿ ½thgen
Nucleic acids research 38 (suppl_2), W109-W117, 2010
Drug resistance mechanisms in colorectal cancer dissected with cell type–specific dynamic logic models
F Eduati, V Doldàn-Martelli, B Klinger, T Cokelaer, A Sieber, F Kogera, ...
Cancer research 77 (12), 3364-3375, 2017
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
I Stelniec‐Klotz, S Legewie, O Tchernitsa, F Witzel, B Klinger, C Sers, ...
Molecular systems biology 8 (1), 601, 2012
The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells
R Redmer, Walz, Klinger, Khouja, Welte, Schäfer
Oncogenesis 6 (1), e291, 2017
An immediate-late gene expression module decodes ERK signal duration
F Uhlitz, A Sieber, E Wyler, R Fritsche‐Guenther, J Meisig, M Landthaler, ...
Molecular Systems Biology 13 (5), 2017
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
JJ Staudacher, IS Naarmann-de Vries, SJ Ujvari, B Klinger, M Kasim, ...
Nucleic acids research 43 (6), 3219-3236, 2015
Computer-assisted curation of a human regulatory core network from the biological literature
P Thomas, P Durek, I Solt, B Klinger, F Witzel, P Schulthess, Y Mayer, ...
Bioinformatics 31 (8), 1258-1266, 2014
Multilevel regulation of HIF-1 signaling by TTP
M Fähling, AB Persson, B Klinger, E Benko, A Steege, M Kasim, A Patzak, ...
Molecular biology of the cell 23 (20), 4129-4141, 2012
Consequences of feedback in signal transduction for targeted therapies
B Klinger, N Blüthgen
Biochemical Society Transactions 42 (4), 770-775, 2014
Modelling signalling networks from perturbation data
M Dorel, B Klinger, T Gross, A Sieber, A Prahallad, E Bosdriesz, ...
Bioinformatics 34 (23), 4079-4086, 2018
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
R Brandt, T Sell, M Luethen, F Uhlitz, B Klinger, P Riemer, ...
Nature Communications 10 (1), 2919, 2019
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A
N Rohwer, F Bindel, C Grimm, SJ Lin, J Wappler, B Klinger, N Blüthgen, ...
Oncotarget 7 (6), 6693, 2016
Reverse engineering gene regulatory networks by modular response analysis–a benchmark
B Klinger, N Blüthgen
Essays in biochemistry 62 (4), 535-547, 2018
Isoform-specific Ras signaling is growth factor dependent
FE Hood, B Klinger, AU Newlaczyl, A Sieber, M Dorel, SP Oliver, ...
Molecular biology of the cell 30 (9), 1108-1117, 2019
Comparative Network Reconstruction using mixed integer programming
E Bosdriesz, A Prahallad, B Klinger, A Sieber, A Bosma, R Bernards, ...
Bioinformatics 34 (17), i997-i1004, 2018
The cancer cell proteome and transcriptome predicts sensitivity to targeted and cytotoxic drugs
M Rydenfelt, M Wongchenko, B Klinger, Y Yan, N Blüthgen
Life science alliance 2 (4), e201900445, 2019
Mathematical Modelling of Molecular Networks in Cancer Cells Using Modular Response Analysis
B Klinger
Logos Berlin, 2016
The system can't perform the operation now. Try again later.
Articles 1–19