Bertram Klinger

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Nils BlüthgenCharité Universitätsmedizin Berlin & Humboldt Universität zu BerlinVerified email at charite.de
Florian UhlitzMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org
Julio Saez RodriguezHeidelberg UniversityVerified email at uni-heidelberg.de
Franziska WitzelCharité/ HU BerlinVerified email at charite.de
Michael SchubertPostdoc, Netherlands Cancer Institute (NKI-AVL)Verified email at nki.nl
Michael FählingProfessor for Molecular Physiology, Charité - Universitätsmedizin BerlinVerified email at charite.de
Ralf MrowkaProfessor at Friedrich-Schiller-University Jena, Faculty of MedicineVerified email at med.uni-jena.de
Federica EduatiTechnische Universiteit EindhovenVerified email at tue.nl
Thomas CokelaerInstitut PasteurVerified email at pasteur.fr
Yu (Brandon) XiaProfessor of Bioengineering, McGill UniversityVerified email at mcgill.ca
Markus LandthalerMax-Delbrück-Center for Molecular Medicine Berlin,IRI Life Sciences Humboldt-Universität zu BerlinVerified email at mdc-berlin.de
Emanuel WylerPostdoc, Berlin Institute for Medical Systems Biology, Max Delbruck Center for MolecularVerified email at mdc-berlin.de
Hanspeter HerzelInstitute for Theoretical BiologyVerified email at biologie.hu-berlin.de
Jonas J. StaudacherCharité - Universiätsmedizin Berlin - Division of Gastroenterology, Infectology and RheumatologyVerified email at charite.de
Thorsten CramerMolecular Tumor Biology, RWTH University Hospital Aachen, GermanyVerified email at ukaachen.de
stefan kempaBIMSB@MDC Berlin-BuchVerified email at mdc-berlin.de
Pascal SchulthessHubrecht Institute, Utrecht, The NetherlandsVerified email at hubrecht.eu
Philippe ThomasGerman Research Center for Artificial IntelligenceVerified email at dfki.de
Ulf LeserKnowledge Management in Bioinformatics, Humboldt-Universität zu BerlinVerified email at informatik.hu-berlin.de
Domonkos TikkGravity R&D, a Taboola companyVerified email at taboola.com

Bertram Klinger

Postdoc in Computational Modelling in Medicine, Charité Universitätsmedizin Berlin

Verified email at charite.de


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Perturbation-response genes reveal signaling footprints in cancer gene expression M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ... Nature Communications 9 (1), 11, 2018	579	2018
Network quantification of EGFR signaling unveils potential for targeted combination therapy B Klinger, A Sieber, R Fritsche‐Guenther, F Witzel, L Berry, ... Molecular systems biology 9 (1), 673, 2013	176	2013
Drug resistance mechanisms in colorectal cancer dissected with cell type–specific dynamic logic models F Eduati, V Doldàn-Martelli, B Klinger, T Cokelaer, A Sieber, F Kogera, ... Cancer research 77 (12), 3364-3375, 2017	106	2017
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium R Brandt, T Sell, M Lüthen, F Uhlitz, B Klinger, P Riemer, ... Nature Communications 10 (1), 2919, 2019	84	2019
Discovering causal signaling pathways through gene-expression patterns JR Parikh, B Klinger, Y Xia, JA Marto, N Blï¿ ½thgen Nucleic acids research 38 (suppl_2), W109-W117, 2010	78	2010
The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells R Redmer, Walz, Klinger, Khouja, Welte, Schäfer Oncogenesis 6 (1), e291, 2017	67	2017
An immediate-late gene expression module decodes ERK signal duration F Uhlitz, A Sieber, E Wyler, R Fritsche‐Guenther, J Meisig, M Landthaler, ... Molecular Systems Biology 13 (5), 2017	63	2017
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS I Stelniec‐Klotz, S Legewie, O Tchernitsa, F Witzel, B Klinger, C Sers, ... Molecular systems biology 8 (1), 601, 2012	62	2012
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum JJ Staudacher, IS Naarmann-de Vries, SJ Ujvari, B Klinger, M Kasim, ... Nucleic acids research 43 (6), 3219-3236, 2015	47	2015
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma U Schoetz, D Klein, J Hess, S Shnayien, S Spoerl, M Orth, S Mutlu, ... Cell death & disease 12 (12), 1162, 2021	45	2021
Isoform-specific Ras signaling is growth factor dependent FE Hood, B Klinger, AU Newlaczyl, A Sieber, M Dorel, SP Oliver, ... Molecular biology of the cell 30 (9), 1108-1117, 2019	38	2019
Modelling signalling networks from perturbation data M Dorel, B Klinger, T Gross, A Sieber, A Prahallad, E Bosdriesz, ... Bioinformatics 34 (23), 4079-4086, 2018	36	2018
SPEED2: inferring upstream pathway activity from differential gene expression M Rydenfelt, B Klinger, M Klünemann, N Blüthgen Nucleic acids research 48 (W1), W307-W312, 2020	35	2020
SFPQ depletion is synthetically lethal with BRAFV600E in colorectal cancer cells K Klotz-Noack, B Klinger, M Rivera, N Bublitz, F Uhlitz, P Riemer, ... Cell reports 32 (12), 2020	32	2020
Consequences of feedback in signal transduction for targeted therapies B Klinger, N Blüthgen Biochemical Society Transactions 42 (4), 770-775, 2014	21	2014
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A N Rohwer, F Bindel, C Grimm, SJ Lin, J Wappler, B Klinger, N Bluethgen, ... Oncotarget 7 (6), 6693, 2016	20	2016
Computer-assisted curation of a human regulatory core network from the biological literature P Thomas, P Durek, I Solt, B Klinger, F Witzel, P Schulthess, Y Mayer, ... Bioinformatics 31 (8), 1258-1266, 2015	19	2015
Multilevel regulation of HIF-1 signaling by TTP M Fähling, AB Persson, B Klinger, E Benko, A Steege, M Kasim, A Patzak, ... Molecular biology of the cell 23 (20), 4129-4141, 2012	18	2012
Reverse engineering gene regulatory networks by modular response analysis–a benchmark B Klinger, N Blüthgen Essays in Biochemistry 62 (4), 535-547, 2018	16	2018
The cancer cell proteome and transcriptome predicts sensitivity to targeted and cytotoxic drugs M Rydenfelt, M Wongchenko, B Klinger, Y Yan, N Blüthgen Life science alliance 2 (4), 2019	14	2019

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