Bertram Klinger
Bertram Klinger
Postdoc in Computational Modelling in Medicine, Charité Universitätsmedizin Berlin
Verified email at charite.de
Title
Cited by
Cited by
Year
Network quantification of EGFR signaling unveils potential for targeted combination therapy
B Klinger, A Sieber, R Fritsche‐Guenther, F Witzel, L Berry, ...
Molecular systems biology 9 (1), 673, 2013
1362013
Perturbation-response genes reveal signaling footprints in cancer gene expression
M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ...
Nature Communications 9 (1), 11, 2018
1082018
Drug resistance mechanisms in colorectal cancer dissected with cell type–specific dynamic logic models
F Eduati, V Doldàn-Martelli, B Klinger, T Cokelaer, A Sieber, F Kogera, ...
Cancer research 77 (12), 3364-3375, 2017
712017
Discovering causal signaling pathways through gene-expression patterns
JR Parikh, B Klinger, Y Xia, JA Marto, N Blï¿ ½thgen
Nucleic acids research 38 (suppl_2), W109-W117, 2010
572010
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
I Stelniec‐Klotz, S Legewie, O Tchernitsa, F Witzel, B Klinger, C Sers, ...
Molecular systems biology 8 (1), 601, 2012
492012
The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells
R Redmer, Walz, Klinger, Khouja, Welte, Schäfer
Oncogenesis 6 (1), e291, 2017
432017
An immediate-late gene expression module decodes ERK signal duration
F Uhlitz, A Sieber, E Wyler, R Fritsche‐Guenther, J Meisig, M Landthaler, ...
Molecular Systems Biology 13 (5), 2017
332017
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
R Brandt, T Sell, M Lüthen, F Uhlitz, B Klinger, P Riemer, ...
Nature communications 10 (1), 1-15, 2019
302019
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
JJ Staudacher, IS Naarmann-de Vries, SJ Ujvari, B Klinger, M Kasim, ...
Nucleic acids research 43 (6), 3219-3236, 2015
302015
Isoform-specific Ras signaling is growth factor dependent
FE Hood, B Klinger, AU Newlaczyl, A Sieber, M Dorel, SP Oliver, ...
Molecular biology of the cell 30 (9), 1108-1117, 2019
162019
Modelling signalling networks from perturbation data
M Dorel, B Klinger, T Gross, A Sieber, A Prahallad, E Bosdriesz, ...
Bioinformatics 34 (23), 4079-4086, 2018
162018
Computer-assisted curation of a human regulatory core network from the biological literature
P Thomas, P Durek, I Solt, B Klinger, F Witzel, P Schulthess, Y Mayer, ...
Bioinformatics 31 (8), 1258-1266, 2015
162015
Multilevel regulation of HIF-1 signaling by TTP
M Fähling, AB Persson, B Klinger, E Benko, A Steege, M Kasim, A Patzak, ...
Molecular biology of the cell 23 (20), 4129-4141, 2012
162012
Consequences of feedback in signal transduction for targeted therapies
B Klinger, N Blüthgen
Biochemical Society Transactions 42 (4), 770-775, 2014
142014
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A
N Rohwer, F Bindel, C Grimm, SJ Lin, J Wappler, B Klinger, N Blüthgen, ...
Oncotarget 7 (6), 6693, 2016
122016
Comparative Network Reconstruction using mixed integer programming
E Bosdriesz, A Prahallad, B Klinger, A Sieber, A Bosma, R Bernards, ...
Bioinformatics 34 (17), i997-i1004, 2018
92018
Reverse engineering gene regulatory networks by modular response analysis–a benchmark
B Klinger, N Bluethgen
Essays In Biochemistry 62 (4), 535-547, 2018
82018
The cancer cell proteome and transcriptome predicts sensitivity to targeted and cytotoxic drugs
M Rydenfelt, M Wongchenko, B Klinger, Y Yan, N Blüthgen
Life science alliance 2 (4), 2019
62019
SPEED2: inferring upstream pathway activity from differential gene expression
M Rydenfelt, B Klinger, M Klünemann, N Blüthgen
Nucleic Acids Research, 2020
52020
SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
K Klotz-Noack, B Klinger, M Rivera, N Bublitz, F Uhlitz, P Riemer, ...
Cell Reports 32 (12), 108184, 2020
42020
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