Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2597 | 2014 |
Partitioning heritability by functional annotation using genome-wide association summary statistics HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ... Nature genetics 47 (11), 1228-1235, 2015 | 2412 | 2015 |
Multiple common variants for celiac disease influencing immune gene expression PCA Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, ... Nature genetics 42 (4), 295-302, 2010 | 1257 | 2010 |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ... Nature genetics 44 (12), 1341-1348, 2012 | 1109 | 2012 |
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease G Trynka, KA Hunt, NA Bockett, J Romanos, V Mistry, A Szperl, SF Bakker, ... Nature genetics 43 (12), 1193-1201, 2011 | 989 | 2011 |
Newly identified genetic risk variants for celiac disease related to the immune response KA Hunt, A Zhernakova, G Turner, GAR Heap, L Franke, M Bruinenberg, ... Nature genetics 40 (4), 395-402, 2008 | 856 | 2008 |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 788 | 2012 |
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjįlmsson, H Xu, C Zang, ... The American Journal of Human Genetics 95 (5), 535-552, 2014 | 675 | 2014 |
Chromatin marks identify critical cell types for fine mapping complex trait variants G Trynka, C Sandor, B Han, H Xu, BE Stranger, XS Liu, S Raychaudhuri Nature genetics 45 (2), 124-130, 2013 | 665 | 2013 |
Fine-mapping inflammatory bowel disease loci to single-variant resolution H Huang, M Fang, L Jostins, M Umićević Mirkov, G Boucher, ... Nature 547 (7662), 173-178, 2017 | 650 | 2017 |
From GWAS to function: using functional genomics to identify the mechanisms underlying complex diseases E Cano-Gamez, G Trynka Frontiers in genetics 11, 424, 2020 | 554 | 2020 |
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis EA Stahl, D Wegmann, G Trynka, J Gutierrez-Achury, R Do, BF Voight, ... Nature genetics 44 (5), 483-489, 2012 | 476 | 2012 |
Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA RSN Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, ... PLoS genetics 7 (8), e1002197, 2011 | 444 | 2011 |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci A Zhernakova, EA Stahl, G Trynka, S Raychaudhuri, EA Festen, L Franke, ... PLoS genetics 7 (2), e1002004, 2011 | 434 | 2011 |
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP A Zhernakova, EM Festen, L Franke, G Trynka, CC van Diemen, ... The American Journal of Human Genetics 82 (5), 1202-1210, 2008 | 333 | 2008 |
The influence of a short-term gluten-free diet on the human gut microbiome MJ Bonder, EF Tigchelaar, X Cai, G Trynka, MC Cenit, B Hrdlickova, ... Genome medicine 8, 1-11, 2016 | 310 | 2016 |
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ... Nature genetics 49 (3), 416-425, 2017 | 307 | 2017 |
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease EAM Festen, P Goyette, T Green, G Boucher, C Beauchamp, G Trynka, ... PLoS genetics 7 (1), e1001283, 2011 | 281 | 2011 |
ImmunoChip study implicates antigen presentation to T cells in narcolepsy J Faraco, L Lin, BR Kornum, EE Kenny, G Trynka, M Einen, TJ Rico, ... PLoS genetics 9 (2), e1003270, 2013 | 265 | 2013 |
Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines E Cano-Gamez, B Soskic, TI Roumeliotis, E So, DJ Smyth, M Baldrighi, ... Nature communications 11 (1), 1801, 2020 | 247 | 2020 |