Dominik Witzigmann
Dominik Witzigmann
Nanomedicines Research Group, Cullis Lab, UBC, Vancouver, Canada
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Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications
A Wicki, D Witzigmann, V Balasubramanian, J Huwyler
Journal of controlled release 200, 138-157, 2015
PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application
P Grossen, D Witzigmann, S Sieber, J Huwyler
Journal of Controlled Release 260, 46-60, 2017
Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment
T Einfalt, D Witzigmann, C Edlinger, S Sieber, R Goers, A Najer, ...
Nature communications 9 (1), 1-12, 2018
Loop-miRs: active microRNAs generated from single-stranded loop regions
J Winter, S Link, D Witzigmann, C Hildenbrand, C Previti, S Diederichs
Nucleic acids research 41 (10), 5503-5512, 2013
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ...
Nature Nanotechnology 14 (12), 1084-1087, 2019
Zebrafish as an early stage screening tool to study the systemic circulation of nanoparticulate drug delivery systems in vivo
S Sieber, P Grossen, P Detampel, S Siegfried, D Witzigmann, J Huwyler
Journal of Controlled Release 264, 180-191, 2017
Variable asialoglycoprotein receptor 1 expression in liver disease: implications for therapeutic intervention
D Witzigmann, L Quagliata, SH Schenk, C Quintavalle, LM Terracciano, ...
Hepatology Research 46 (7), 686-696, 2016
Lipid-based DNA therapeutics: hallmarks of non-viral gene delivery
J Buck, P Grossen, PR Cullis, J Huwyler, D Witzigmann
ACS nano 13 (4), 3754-3782, 2019
Oral delivery of vancomycin by tetraether lipid liposomes
P Uhl, S Pantze, P Storck, J Parmentier, D Witzigmann, G Hofhaus, ...
European Journal of Pharmaceutical Sciences 108, 111-118, 2017
Hepatocyte targeting using pegylated asialofetuin-conjugated liposomes
P Detampel, D Witzigmann, S Krähenbühl, J Huwyler
Journal of drug targeting 22 (3), 232-241, 2014
Zebrafish as a preclinical in vivo screening model for nanomedicines
S Sieber, P Grossen, J Bussmann, F Campbell, A Kros, D Witzigmann, ...
Advanced drug delivery reviews 151, 152-168, 2019
Biocompatible polymer–peptide hybrid-based DNA nanoparticles for gene delivery
D Witzigmann, D Wu, SH Schenk, V Balasubramanian, W Meier, ...
ACS applied materials & interfaces 7 (19), 10446-10456, 2015
Lipid nanoparticle technology for clinical translation of siRNA therapeutics
JA Kulkarni, D Witzigmann, S Chen, PR Cullis, R van der Meel
Accounts of chemical research 52 (9), 2435-2444, 2019
Zebrafish as a predictive screening model to assess macrophage clearance of liposomes in vivo
S Sieber, P Grossen, P Uhl, P Detampel, W Mier, D Witzigmann, ...
Nanomedicine: Nanotechnology, Biology and Medicine 17, 82-93, 2019
PDMS-b-PMOXA polymersomes for hepatocyte targeting and assessment of toxicity
K Kiene, SH Schenk, F Porta, A Ernst, D Witzigmann, P Grossen, ...
European Journal of Pharmaceutics and Biopharmaceutics 119, 322-332, 2017
Formation of lipid and polymer based gold nanohybrids using a nanoreactor approach
D Witzigmann, S Sieber, F Porta, P Grossen, A Bieri, N Strelnikova, ...
RSC advances 5 (91), 74320-74328, 2015
Functionalized solid-sphere peg-b-pcl nanoparticles to target brain capillary endothelial cells in vitro
P Grossen, G Québatte, D Witzigmann, C Prescianotto-Baschong, ...
Journal of Nanomaterials 2016, 2016
Translating nanomedicines: thinking beyond materials? A young investigator’s reply to ‘the novelty bubble’
D Witzigmann, S Hak, R van der Meel
J Control Release 290, 138-140, 2018
Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads
JA Kulkarni, D Witzigmann, J Leung, R van der Meel, J Zaifman, ...
Nanoscale 11 (18), 9023-9031, 2019
Secreted matrix metalloproteinase-9 of proliferating smooth muscle cells as a trigger for drug release from stent surface polymers in coronary arteries
DG Gliesche, J Hussner, D Witzigmann, F Porta, T Glatter, A Schmidt, ...
Molecular pharmaceutics 13 (7), 2290-2300, 2016
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