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Dominik Witzigmann
Dominik Witzigmann
NanoVation Therapeutics
Geverifieerd e-mailadres voor unibas.ch - Homepage
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Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications
A Wicki, D Witzigmann, V Balasubramanian, J Huwyler
Journal of controlled release 200, 138-157, 2015
19082015
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ...
Nature nanotechnology 14 (12), 1084-1087, 2019
9562019
mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
L Schoenmaker, D Witzigmann, JA Kulkarni, R Verbeke, G Kersten, ...
International journal of pharmaceutics 601, 120586, 2021
8172021
The current landscape of nucleic acid therapeutics
JA Kulkarni, D Witzigmann, SB Thomson, S Chen, BR Leavitt, PR Cullis, ...
Nature nanotechnology 16 (6), 630-643, 2021
6452021
PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application
P Grossen, D Witzigmann, S Sieber, J Huwyler
Journal of Controlled Release 260, 46-60, 2017
4002017
Lipid nanoparticle technology for clinical translation of siRNA therapeutics
JA Kulkarni, D Witzigmann, S Chen, PR Cullis, R van der Meel
Accounts of chemical research 52 (9), 2435-2444, 2019
3172019
Lipid-based DNA therapeutics: hallmarks of non-viral gene delivery
J Buck, P Grossen, PR Cullis, J Huwyler, D Witzigmann
ACS nano 13 (4), 3754-3782, 2019
2482019
The role of lipid components in lipid nanoparticles for vaccines and gene therapy
CH Albertsen, JA Kulkarni, D Witzigmann, M Lind, K Petersson, ...
Advanced drug delivery reviews 188, 114416, 2022
2402022
Lipid nanoparticle technology for therapeutic gene regulation in the liver
D Witzigmann, JA Kulkarni, J Leung, S Chen, PR Cullis, R van der Meel
Advanced drug delivery reviews 159, 344-363, 2020
2252020
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels
T Rothgangl, MK Dennis, PJC Lin, R Oka, D Witzigmann, L Villiger, W Qi, ...
Nature biotechnology 39 (8), 949-957, 2021
2212021
On the role of helper lipids in lipid nanoparticle formulations of siRNA
JA Kulkarni, D Witzigmann, J Leung, YYC Tam, PR Cullis
Nanoscale 11 (45), 21733-21739, 2019
2192019
The biomolecular corona of lipid nanoparticles for gene therapy
V Francia, RM Schiffelers, PR Cullis, D Witzigmann
Bioconjugate chemistry 31 (9), 2046-2059, 2020
1512020
Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment
T Einfalt, D Witzigmann, C Edlinger, S Sieber, R Goers, A Najer, ...
Nature communications 9 (1), 1-12, 2018
1342018
Zebrafish as a preclinical in vivo screening model for nanomedicines
S Sieber, P Grossen, J Bussmann, F Campbell, A Kros, D Witzigmann, ...
Advanced drug delivery reviews 151, 152-168, 2019
1252019
Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads
JA Kulkarni, D Witzigmann, J Leung, R van der Meel, J Zaifman, ...
Nanoscale 11 (18), 9023-9031, 2019
962019
Zebrafish as an early stage screening tool to study the systemic circulation of nanoparticulate drug delivery systems in vivo
S Sieber, P Grossen, P Detampel, S Siegfried, D Witzigmann, J Huwyler
Journal of Controlled Release 264, 180-191, 2017
962017
Oral delivery of vancomycin by tetraether lipid liposomes
P Uhl, S Pantze, P Storck, J Parmentier, D Witzigmann, G Hofhaus, ...
European Journal of Pharmaceutical Sciences 108, 111-118, 2017
812017
Variable asialoglycoprotein receptor 1 expression in liver disease: Implications for therapeutic intervention
D Witzigmann, L Quagliata, SH Schenk, C Quintavalle, LM Terracciano, ...
Hepatology Research 46 (7), 686-696, 2016
772016
Anionic lipid nanoparticles preferentially deliver mRNA to the hepatic reticuloendothelial system
R Pattipeiluhu, G Arias‐Alpizar, G Basha, KYT Chan, J Bussmann, ...
Advanced Materials 34 (16), 2201095, 2022
752022
Rapid optimization of liposome characteristics using a combined microfluidics and design-of-experiment approach
M Sedighi, S Sieber, F Rahimi, MA Shahbazi, AH Rezayan, J Huwyler, ...
Drug delivery and translational research 9, 404-413, 2019
712019
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