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claire chaussade
claire chaussade
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Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
C Chaussade, GW Rewcastle, JD Kendall, WA Denny, K Cho, ...
Biochemical Journal 404 (3), 449-458, 2007
2592007
Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells
H Tronchere, J Laporte, C Pendaries, C Chaussade, L Liaubet, L Pirola, ...
Journal of Biological Chemistry 279 (8), 7304-7312, 2004
1672004
The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia
N Gallay, C Dos Santos, L Cuzin, M Bousquet, V Simmonet Gouy, ...
Leukemia 23 (6), 1029-1038, 2009
1482009
Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of …
L Pirola, S Bonnafous, AM Johnston, C Chaussade, F Portis, ...
Journal of Biological Chemistry 278 (18), 15641-15651, 2003
1422003
Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat
GC Smith, C Chaussade, M Vickers, J Jensen, PR Shepherd
Diabetologia 51, 2309-2317, 2008
1072008
Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148
JR Whiteford, X Xian, C Chaussade, B Vanhaesebroeck, S Nourshargh, ...
Molecular biology of the cell 22 (19), 3609-3624, 2011
972011
Inactivation of the class II PI3K-C2β potentiates insulin signaling and sensitivity
S Alliouachene, B Bilanges, G Chicanne, KE Anderson, W Pearce, K Ali, ...
Cell reports 13 (9), 1881-1894, 2015
882015
Expression of Myotubularin by an Adenoviral Vector Demonstrates Its Function as a Phosphatidylinositol 3-Phosphate [PtdIns(3)P] Phosphatase in Muscle Cell Lines …
C Chaussade, L Pirola, S Bonnafous, F Blondeau, S Brenz-Verca, ...
Molecular Endocrinology 17 (12), 2448-2460, 2003
862003
Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110α inhibitors
JD Kendall, GW Rewcastle, R Frederick, C Mawson, WA Denny, ...
Bioorganic & medicinal chemistry 15 (24), 7677-7687, 2007
722007
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
B Bilanges, S Alliouachene, W Pearce, D Morelli, G Szabadkai, YL Chung, ...
Nature communications 8 (1), 1804, 2017
692017
Essential role of class II PI3K-C2α in platelet membrane morphology
C Valet, G Chicanne, C Severac, C Chaussade, MA Whitehead, C Cabou, ...
Blood, The Journal of the American Society of Hematology 126 (9), 1128-1137, 2015
632015
Functional differences between two classes of oncogenic mutation in the PIK3CA gene
C Chaussade, K Cho, C Mawson, GW Rewcastle, PR Shepherd
Biochemical and biophysical research communications 381 (4), 577-581, 2009
582009
Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes
M Naïmi, N Gautier, C Chaussade, AM Valverde, D Accili, ...
Endocrinology 148 (5), 2424-2434, 2007
562007
Both p110α and p110β isoforms of phosphatidylinositol 3‐OH‐kinase are required for insulin signalling in the hypothalamus
A Tups, GM Anderson, M Rizwan, RA Augustine, C Chaussade, ...
Journal of neuroendocrinology 22 (6), 534-542, 2010
512010
Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity
L Beltran, C Chaussade, B Vanhaesebroeck, PR Cutillas
Proceedings of the National Academy of Sciences 108 (39), 16217-16222, 2011
472011
Discovery of pyrazolo [1, 5-a] pyridines as p110α-selective PI3 kinase inhibitors
JD Kendall, PD O’Connor, AJ Marshall, R Frédérick, ES Marshall, CL Lill, ...
Bioorganic & medicinal chemistry 20 (1), 69-85, 2012
422012
Novel pyrazolo [1, 5-a] pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR
JD Kendall, AC Giddens, KY Tsang, R Frédérick, ES Marshall, R Singh, ...
Bioorganic & medicinal chemistry 20 (1), 58-68, 2012
412012
Phosphoinositide-3-kinase (PI3K) inhibitors: identification of new scaffolds using virtual screening
R Frédérick, C Mawson, JD Kendall, C Chaussade, GW Rewcastle, ...
Bioorganic & medicinal chemistry letters 19 (20), 5842-5847, 2009
332009
Synthesis of Functionalized Pyrazolo [1, 5-a] pyridines:[3+ 2] Cycloaddition of N-Aminopyridines and α, β-Unsaturated Carbonyl Compounds/Alkenes at Room Temperature
C Ravi, S Samanta, DC Mohan, NNK Reddy, S Adimurthy
Synthesis 49 (11), 2513-2522, 2017
312017
Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice
S Alliouachene, B Bilanges, C Chaussade, W Pearce, LC Foukas, ...
Diabetologia 59, 1503-1512, 2016
272016
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Artikelen 1–20