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James Bayrer, MD,PhD
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Enterochromaffin cells are gut chemosensors that couple to sensory neural pathways
NW Bellono, JR Bayrer, DB Leitch, J Castro, C Zhang, TA O’Donnell, ...
Cell 170 (1), 185-198. e16, 2017
6912017
Advances in enteric neurobiology: the “brain” in the gut in health and disease
S Kulkarni, J Ganz, J Bayrer, L Becker, M Bogunovic, M Rao
Journal of Neuroscience 38 (44), 9346-9354, 2018
872018
Intestinal organoids: new frontiers in the study of intestinal disease and physiology
TE Wallach, JR Bayrer
Journal of pediatric gastroenterology and nutrition 64 (2), 180-185, 2017
802017
Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones
CB Herber, WC Krause, L Wang, JR Bayrer, A Li, M Schmitz, A Fields, ...
Nature communications 10 (1), 163, 2019
712019
Dimerization of doublesex is mediated by a cryptic ubiquitin-associated domain fold: implications for sex-specific gene regulation
JR Bayrer, W Zhang, MA Weiss
Journal of Biological Chemistry 280 (38), 32989-32996, 2005
712005
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival
JR Bayrer, H Wang, R Nattiv, M Suzawa, HS Escusa, RJ Fletterick, ...
Nature communications 9 (1), 4055, 2018
652018
Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs
JR Bayrer, S Mukkamala, EP Sablin, P Webb, RJ Fletterick
Proceedings of the National Academy of Sciences 112 (8), 2467-2472, 2015
622015
Gut enterochromaffin cells drive visceral pain and anxiety
JR Bayrer, J Castro, A Venkataraman, KK Touhara, ND Rossen, ...
Nature 616 (7955), 137-142, 2023
362023
Doublesex and the regulation of sexual dimorphism in Drosophila melanogaster: structure, function, and mutagenesis of a female-specific domain
Y Yang, W Zhang, JR Bayrer, MA Weiss
Journal of biological chemistry 283 (11), 7280-7292, 2008
282008
A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance
K Man, C Bowman, KN Braverman, V Escalante, Y Tian, JE Bisanz, ...
Proceedings of the National Academy of Sciences 117 (50), 32029-32037, 2020
72020
Expression, crystallization and preliminary X-ray characterization of the Drosophila transcription factor Doublesex
J Bayrer, Z Wan, B Li, MA Weiss
Acta Crystallographica Section D: Biological Crystallography 60 (7), 1328-1330, 2004
42004
Gut enterochromaffin cells are critical drivers of visceral pain and anxiety
JR Bayrer, J Castro, A Venkataraman, KK Touhara, ND Rossen, ...
BioRxiv, 2022.04. 04.486775, 2022
12022
Tu1824 Targeting Intestinal Stem Cells to Promote Healing in Inflammatory Bowel Disease
JR Bayrer, R Fletterick, H Ingraham
Gastroenterology 148 (4), S-911-S-912, 2015
12015
SPARC‐Mapping gut‐spinal cord connections in visceral pain
RD Morrie, J Bayrer, S Brierley, H Ingraham, D Julius
The FASEB Journal 34 (S1), 1-1, 2020
2020
948–Nuclear Receptor Liver Receptor Homolog-1 Promotes Intestinal Notch Signaling and Enteroendocrine Cell Development
PK Choksi, HA Ingraham, J Bayrer
Gastroenterology 156 (6), S-202, 2019
2019
Estrogen Signaling in Arcuate Kiss1 Neurons Suppresses a Sex-Dependent Circuit That Promotes Dense Strong Bones in Female Mice
CB Herber, WC Krause, L Wang, JR Bayrer, A Li, M Schmitz, A Fields, ...
bioRxiv, 315283, 2018
2018
273-Nuclear Receptor LRH-1 Mitigates Intestinal Inflammatory Disease by Promoting Stem Cell Survival and Directing Normal Epithelial Composition
J Bayrer, H Escusa, OD Kein, H Ingraham
Gastroenterology 154 (6), S-67, 2018
2018
Sa1803 Dissecting the Oncogenic Activity of the Nuclear Receptor LRH-1 in the Colon
JR Bayrer, S Mukkamala, E Sablin, R Fletterick
Gastroenterology 5 (146), S-299, 2014
2014
The Doublesex transcription factor: Structural and functional studies of a sex-determining factor
JR Bayrer
Case Western Reserve University, 2006
2006
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Artikelen 1–19