Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy Y Mimura, T Katoh, R Saldova, R O’Flaherty, T Izumi, Y Mimura-Kimura, ... Protein & cell 9 (1), 47-62, 2018 | 195 | 2018 |
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing R O’Flaherty, A Bergin, E Flampouri, LM Mota, I Obaidi, A Quigley, Y Xie, ... Biotechnology advances 43, 107552, 2020 | 163 | 2020 |
NIST interlaboratory study on glycosylation analysis of monoclonal antibodies: comparison of results from diverse analytical methods MLA De Leoz, DL Duewer, A Fung, L Liu, HK Yau, O Potter, GO Staples, ... Molecular & Cellular Proteomics 19 (1), 11-30, 2020 | 107 | 2020 |
High-throughput serum N-glycomics: method comparison and application to study rheumatoid arthritis and pregnancy-associated changes MW Karli R. Reiding, Albert Bondt, René Hennig, Richard Gardner, Roisin O ... Molecular and Cellular Proteomics, 2018 | 84* | 2018 |
The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins R O’Flaherty, I Trbojević-Akmačić, G Greville, PM Rudd, G Lauc Expert review of proteomics 15 (1), 13-29, 2018 | 64 | 2018 |
Automated, high-throughput serum glycoprofiling platform H Stöckmann, R O'Flaherty, B Adamczyk, R Saldova, PM Rudd Integrative biology 7 (9), 1026-1032, 2015 | 60 | 2015 |
Prediction of metabolic clusters in early-lactation dairy cows using models based on milk biomarkers J De Koster, M Salavati, C Grelet, MA Crowe, E Matthews, R O'Flaherty, ... Journal of dairy science 102 (3), 2631-2644, 2019 | 50 | 2019 |
Genome‐wide association for milk production and lactation curve parameters in Holstein dairy cows H Atashi, M Salavati, J De Koster, J Ehrlich, M Crowe, G Opsomer, ... Journal of Animal Breeding and Genetics 137 (3), 292-304, 2020 | 47 | 2020 |
N-Glycosylation of Serum IgG and Total Glycoproteins in MAN1B1 Deficiency R Saldova, H Stöckmann, R O’Flaherty, DJ Lefeber, J Jaeken, PM Rudd Journal of proteome research 14 (10), 4402-4412, 2015 | 33 | 2015 |
IgG Fc glycosylation as an axis of humoral immunity in childhood HD Cheng, I Tirosh, N de Haan, H Stöckmann, B Adamczyk, CA McManus, ... Journal of Allergy and Clinical Immunology 145 (2), 710-713. e9, 2020 | 30 | 2020 |
Deep phenotyping classical galactosemia: clinical outcomes and biochemical markers MM Welsink-Karssies, S Ferdinandusse, GJ Geurtsen, CEM Hollak, ... Brain communications 2 (1), fcaa006, 2020 | 30 | 2020 |
Synthesis, structural elucidation, and biochemical analysis of immunoactive glucuronosyl diacylglycerides of mycobacteria and corynebacteria B Cao, X Chen, Y Yamaryo-Botte, MB Richardson, KL Martin, ... The Journal of Organic Chemistry 78 (6), 2175-2190, 2013 | 30 | 2013 |
Hypoxia Alters Epigenetic and N-Glycosylation Profiles of Ovarian and Breast Cancer Cell Lines in-vitro G Greville, E Llop, C Huang, J Creagh-Flynn, S Pfister, R O'Flaherty, ... Frontiers in Oncology 10, 1218, 2020 | 27 | 2020 |
High-throughput glycomics and glycoproteomics G Lauc, M Wuhrer Springer New York, 2017 | 25* | 2017 |
Region-Specific Characterization of N-Glycans in the Striatum and Substantia Nigra of an Adult Rodent Brain J Samal, R Saldova, PM Rudd, A Pandit, R O’Flaherty Analytical Chemistry 92 (19), 12842-12851, 2020 | 24 | 2020 |
High-Throughput Analysis of the Plasma N-Glycome by UHPLC B Adamczyk, H Stöckmann, R O’Flaherty, NG Karlsson, PM Rudd High-Throughput Glycomics and Glycoproteomics: Methods and Protocols, 97-108, 2017 | 24 | 2017 |
A robust and versatile automated glycoanalytical technology for serum antibodies and acute phase proteins: ovarian cancer case study R O'Flaherty, M Muniyappa, I Walsh, H Stöckmann, M Hilliard, R Hutson, ... Molecular & Cellular Proteomics 18 (11), 2191-2206, 2019 | 21 | 2019 |
Aminoquinoline Fluorescent Labels Obstruct Efficient Removal of N-Glycan Core α(1–6) Fucose by Bovine Kidney α-l-Fucosidase (BKF) R O’Flaherty, AM Harbison, PJ Hanley, CH Taron, E Fadda, PM Rudd Journal of Proteome Research 16 (11), 4237-4243, 2017 | 20 | 2017 |
Fertility in classical galactosaemia, a study of N-glycan, hormonal and inflammatory gene interactions HO Colhoun, EM Rubio Gozalbo, AM Bosch, I Knerr, C Dawson, J Brady, ... Orphanet journal of rare diseases 13, 1-13, 2018 | 18 | 2018 |
Validation of an automated ultraperformance liquid chromatography IgG N-glycan analytical method applicable to classical galactosaemia HO Colhoun, EP Treacy, M MacMahon, PM Rudd, M Fitzgibbon, ... Annals of Clinical Biochemistry 55 (5), 593-603, 2018 | 18 | 2018 |