5-Hydroxytryptamine4 Receptor Activation of the Extracellular Signal-regulated Kinase Pathway Depends on Src Activation but Not on G Protein or β-Arrestin … G Barthet, B Framery, F Gaven, L Pellissier, E Reiter, S Claeysen, ... Molecular biology of the cell 18 (6), 1979-1991, 2007 | 94 | 2007 |
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene CH Alves, A Sanz Sanz, B Park, LP Pellissier, N Tanimoto, SC Beck, ... Human molecular genetics 22 (1), 35-50, 2013 | 91 | 2013 |
μ opioid receptor, social behaviour and autism spectrum disorder: reward matters LP Pellissier, J Gandía, T Laboute, JAJ Becker, J Le Merrer British journal of pharmacology 175 (14), 2750-2769, 2018 | 90 | 2018 |
The CRB1 and adherens junction complex proteins in retinal development and maintenance CH Alves, LP Pellissier, J Wijnholds Progress in retinal and eye research 40, 35-52, 2014 | 90 | 2014 |
G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient LP Pellissier, G Barthet, F Gaven, E Cassier, E Trinquet, JP Pin, P Marin, ... Journal of Biological Chemistry 286 (12), 9985-9997, 2011 | 90 | 2011 |
Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis LP Pellissier, CH Alves, PM Quinn, RM Vos, N Tanimoto, DMS Lundvig, ... PLoS genetics 9 (12), e1003976, 2013 | 86 | 2013 |
β‐arrestin1 phosphorylation by GRK5 regulates G protein‐independent 5‐HT4 receptor signalling G Barthet, G Carrat, E Cassier, B Barker, F Gaven, M Pillot, B Framery, ... The EMBO journal 28 (18), 2706-2718, 2009 | 85 | 2009 |
Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors LP Pellissier, J Sallander, M Campillo, F Gaven, E Queffeulou, M Pillot, ... Molecular Pharmacology 75 (4), 982-990, 2009 | 83 | 2009 |
Mice lacking GPR88 show motor deficit, improved spatial learning, and low anxiety reversed by delta opioid antagonist AC Meirsman, J Le Merrer, LP Pellissier, J Diaz, D Clesse, BL Kieffer, ... Biological psychiatry 79 (11), 917-927, 2016 | 81 | 2016 |
Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models LP Pellissier, PM Quinn, CH Alves, RM Vos, J Klooster, JG Flannery, ... Human molecular genetics 24 (11), 3104-3118, 2015 | 71 | 2015 |
Benzimidazole Derivatives as New Serotonin 5-HT6 Receptor Antagonists. Molecular Mechanisms of Receptor Inactivation T De La Fuente, M Martín-Fontecha, J Sallander, B Benhamú, M Campillo, ... Journal of medicinal chemistry 53 (3), 1357-1369, 2010 | 65 | 2010 |
Modifying Ligand-Induced and Constitutive Signaling of the Human 5-HT4 Receptor WC Chang, JK Ng, T Nguyen, L Pellissier, S Claeysen, EC Hsiao, ... PloS one 2 (12), e1317, 2007 | 64 | 2007 |
Specific tools for targeting and expression in Müller glial cells LP Pellissier, RM Hoek, RM Vos, WM Aartsen, RR Klimczak, SA Hoyng, ... Molecular Therapy-Methods & Clinical Development 1, 14009, 2014 | 62 | 2014 |
Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa CH Alves, LP Pellissier, RM Vos, M Garcia Garrido, V Sothilingam, ... Human molecular genetics 23 (13), 3384-3401, 2014 | 57 | 2014 |
CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice LP Pellissier, DMS Lundvig, N Tanimoto, J Klooster, RM Vos, F Richard, ... Human molecular genetics 23 (14), 3759-3771, 2014 | 56 | 2014 |
The CRB1 complex: following the trail of crumbs to a feasible gene therapy strategy PM Quinn, LP Pellissier, J Wijnholds Frontiers in neuroscience 11, 175, 2017 | 55 | 2017 |
GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors WM Aartsen, KWR van Cleef, LP Pellissier, RM Hoek, RM Vos, B Blits, ... PloS one 5 (8), e12387, 2010 | 54 | 2010 |
β-arrestin signalling and bias in hormone-responsive GPCRs E Reiter, MA Ayoub, LP Pellissier, F Landomiel, A Musnier, A Tréfier, ... Molecular and Cellular Endocrinology 449, 28-41, 2017 | 41 | 2017 |
LIT-001, the first nonpeptide oxytocin receptor agonist that improves social interaction in a mouse model of autism MC Frantz, LP Pellissier, E Pflimlin, S Loison, J Gandía, C Marsol, ... Journal of Medicinal Chemistry 61 (19), 8670-8692, 2018 | 32 | 2018 |
Recombinant AAV-Crumbs homologue composition and methods for treating LCA-8 and progressive RP J Wijnholds, LPF Pellissier US Patent 11,246,947, 2022 | 28 | 2022 |