Volgen
Raimond Heukers
Raimond Heukers
VU Amsterdam
Geverifieerd e-mailadres voor heukers.nl
Titel
Geciteerd door
Geciteerd door
Jaar
Targeting tumors with nanobodies for cancer imaging and therapy
S Oliveira, R Heukers, J Sornkom, RJ Kok, PMPB en Henegouwen
Journal of Controlled Release 172 (3), 607-617, 2013
2352013
EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer
PBAA Van Driel, MC Boonstra, MD Slooter, R Heukers, MA Stammes, ...
Journal of Controlled Release 229, 93-105, 2016
1542016
Nanobody-albumin nanoparticles (NANAPs) for the delivery of a multikinase inhibitor 17864 to EGFR overexpressing tumor cells
I Altintas, R Heukers, R van der Meel, M Lacombe, M Amidi, ...
Journal of Controlled Release 165 (2), 110-118, 2013
1192013
Nanobody–photosensitizer conjugates for targeted photodynamic therapy
R Heukers, PMPB en Henegouwen, S Oliveira
Nanomedicine: Nanotechnology, Biology and Medicine 10 (7), 1441-1451, 2014
1072014
Targeting hepatocyte growth factor receptor (Met) positive tumor cells using internalizing nanobody-decorated albumin nanoparticles
R Heukers, I Altintas, S Raghoenath, E De Zan, R Pepermans, ...
Biomaterials 35 (1), 601-610, 2014
832014
Endocytosis of EGFR requires its kinase activity and N-terminal transmembrane dimerization motif
R Heukers, JF Vermeulen, F Fereidouni, AN Bader, J Voortman, ...
Journal of cell science 126 (21), 4900-4912, 2013
742013
Nanobody-targeted photodynamic therapy selectively kills viral GPCR-expressing glioblastoma cells
TWM De Groof, V Mashayekhi, TS Fan, ND Bergkamp, J Sastre Toraño, ...
Molecular pharmaceutics 16 (7), 3145-3156, 2019
702019
EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells
EP Moiseeva, R Heukers, MM Manson
Carcinogenesis 28 (2), 435-445, 2007
672007
The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth
R Heukers, TS Fan, RH de Wit, JR van Senten, TWM De Groof, ...
Oncogene 37 (30), 4110-4121, 2018
662018
Heterogeneity assessment of antibody-derived therapeutics at the intact and middle-up level by low-flow sheathless capillary electrophoresis-mass spectrometry
R Haselberg, T De Vijlder, R Heukers, MJ Smit, EP Romijn, GW Somsen, ...
Analytica chimica acta 1044, 181-190, 2018
612018
Nanobodies: New avenues for imaging, stabilizing and modulating GPCRs
TWM De Groof, V Bobkov, R Heukers, MJ Smit
Molecular and cellular endocrinology 484, 15-24, 2019
582019
Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions
V Bobkov, AM Zarca, A Van Hout, M Arimont, J Doijen, M Bialkowska, ...
Biochemical pharmacology 158, 413-424, 2018
552018
Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists
A Işbilir, J Möller, M Arimont, V Bobkov, C Perpiñá-Viciano, C Hoffmann, ...
Proceedings of the National Academy of Sciences 117 (46), 29144-29154, 2020
542020
Nanobodies detecting and modulating GPCRs outside in and inside out
R Heukers, TWM De Groof, MJ Smit
Current Opinion in Cell Biology 57, 115-122, 2019
502019
CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry
A Van Hout, A Klarenbeek, V Bobkov, J Doijen, M Arimont, C Zhao, ...
Biochemical pharmacology 158, 402-412, 2018
462018
Inhibition of tumor growth by targeted anti-EGFR/IGF-1R nanobullets depends on efficient blocking of cell survival pathways
R van der Meel, S Oliveira, I Altintas, R Heukers, EHE Pieters, ...
Molecular pharmaceutics 10 (10), 3717-3727, 2013
422013
Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling
Cancer Research 75 (16), 3373-3383, 2015
402015
VHH-photosensitizer conjugates for targeted photodynamic therapy of met-overexpressing tumor cells
R Heukers, V Mashayekhi, M Ramirez-Escudero, H de Haard, TC Verrips, ...
Antibodies 8 (2), 26, 2019
352019
CXCR4-specific nanobodies as potential therapeutics for WHIM syndrome
RH de Wit, R Heukers, HJ Brink, A Arsova, D Maussang, P Cutolo, ...
Journal of Pharmacology and Experimental Therapeutics 363 (1), 35-44, 2017
332017
Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design
A Amcheslavsky, AL Wallace, M Ejemel, Q Li, CT McMahon, M Stoppato, ...
Scientific reports 11 (1), 2751, 2021
272021
Het systeem kan de bewerking nu niet uitvoeren. Probeer het later opnieuw.
Artikelen 1–20