William Lockwood
William Lockwood
Senior Scientist, British Columbia Cancer Agency - Associate Professor, University of British
Verified email at bccrc.ca - Homepage
Title
Cited by
Cited by
Year
PIK3CA mutations and copy number gains in human lung cancers
H Yamamoto, H Shigematsu, M Nomura, WW Lockwood, M Sato, ...
Cancer research 68 (17), 6913-6921, 2008
4462008
Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins
WW Lockwood, K Zejnullahu, JE Bradner, H Varmus
Proceedings of the National Academy of Sciences 109 (47), 19408-19413, 2012
3042012
Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells
J Soh, N Okumura, WW Lockwood, H Yamamoto, H Shigematsu, ...
PloS one 4 (10), e7464, 2009
2192009
Lung cancer cell lines as tools for biomedical discovery and research
AF Gazdar, L Girard, WW Lockwood, WL Lam, JD Minna
Journal of the National Cancer Institute 102 (17), 1310-1321, 2010
2122010
Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines
J Gandhi, J Zhang, Y Xie, J Soh, H Shigematsu, W Zhang, H Yamamoto, ...
PloS one 4 (2), e4576, 2009
2102009
TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer
DT Starczynowski, WW Lockwood, S Deléhouzée, R Chari, J Wegrzyn, ...
The Journal of clinical investigation 121 (10), 4095-4105, 2011
1572011
Lung cancer signatures in plasma based on proteome profiling of mouse tumor models
A Taguchi, K Politi, SJ Pitteri, WW Lockwood, VM Faça, K Kelly-Spratt, ...
Cancer cell 20 (3), 289-299, 2011
1552011
Recent advances in array comparative genomic hybridization technologies and their applications in human genetics
WW Lockwood, R Chari, B Chi, WL Lam
European Journal of Human Genetics 14 (2), 139-148, 2006
1532006
High resolution analysis of non‐small cell lung cancer cell lines by whole genome tiling path array CGH
C Garnis, WW Lockwood, E Vucic, Y Ge, L Girard, JD Minna, AF Gazdar, ...
International Journal of Cancer 118 (6), 1556-1564, 2006
1462006
MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors
T Kubo, H Yamamoto, WW Lockwood, I Valencia, J Soh, M Peyton, M Jida, ...
International journal of cancer 124 (8), 1778-1784, 2009
1332009
DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers
WW Lockwood, R Chari, BP Coe, L Girard, C Macaulay, S Lam, ...
Oncogene 27 (33), 4615-4624, 2008
1222008
Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines
R Somwar, H Erdjument-Bromage, E Larsson, D Shum, WW Lockwood, ...
Proceedings of the National Academy of Sciences 108 (39), 16375-16380, 2011
1062011
Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma
WW Lockwood, R Chari, BP Coe, KL Thu, C Garnis, CA Malloff, ...
PLoS Med 7 (7), e1000315, 2010
1052010
Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma
AM Unni, WW Lockwood, K Zejnullahu, SQ Lee-Lin, H Varmus
Elife 4, e06907, 2015
882015
Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis
EA Marshall, KW Ng, SHY Kung, EM Conway, VD Martinez, EC Halvorsen, ...
Molecular cancer 15 (1), 1-15, 2016
852016
Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer
BP Coe, WW Lockwood, L Girard, R Chari, C Macaulay, S Lam, ...
British journal of cancer 94 (12), 1927-1935, 2006
852006
Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma
L Lin, AJ Bass, WW Lockwood, Z Wang, AL Silvers, DG Thomas, ...
Proceedings of the National Academy of Sciences 109 (11), 4251-4256, 2012
832012
Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer
R Chari, KL Thu, IM Wilson, WW Lockwood, KM Lonergan, BP Coe, ...
Cancer and Metastasis Reviews 29 (1), 73-93, 2010
752010
Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability
KL Thu, EA Vucic, R Chari, W Zhang, WW Lockwood, JC English, R Fu, ...
PloS one 7 (3), e33003, 2012
702012
An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer
R Chari, BP Coe, EA Vucic, WW Lockwood, WL Lam
BMC systems biology 4 (1), 1-14, 2010
702010
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