Monique van der Wijst
Monique van der Wijst
Assistant professor Genetics, University Medical Center Groningen
Verified email at
Cited by
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Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs
MGP van der Wijst, H Brugge, DH de Vries, P Deelen, MA Swertz, L study, ...
Nature Genetics, 2018
Science Forum: The single-cell eQTLGen consortium
MGP van der Wijst, DH de Vries, HE Groot, G Trynka, CC Hon, MJ Bonder, ...
Elife 9, e52155, 2020
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19
MGP van der Wijst, SE Vazquez, GC Hartoularos, P Bastard, T Grant, ...
Science translational medicine 13 (612), eabh2624, 2021
Mitochondrial epigenetics: an overlooked layer of regulation?
MGP van der Wijst, MG Rots
Trends in Genetics 31 (7), 353-356, 2015
Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression
MGP van der Wijst, AY van Tilburg, MHJ Ruiters, MG Rots
Scientific reports 7 (1), 1-15, 2017
Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase
MGP van der Wijst, M Venkiteswaran, H Chen, GL Xu, T Plösch, MG Rots
Epigenetics 10 (8), 671-676, 2015
Regulation of mitochondrial gene expression, the epigenetic enigma
A Mposhi, MG Van der Wijst, KN Faber, MG Rots
Front Biosci (Landmark Ed) 22, 1099-113, 2017
Nrf2, the master redox switch: the Achilles' heel of ovarian cancer?
MGP van der Wijst, R Brown, MG Rots
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (2), 494-509, 2014
An integrative approach for building personalized gene regulatory networks for precision medicine
MGP Van Der Wijst, DH de Vries, H Brugge, HJ Westra, L Franke
Genome medicine 10 (1), 1-15, 2018
Deconvolution of bulk blood eQTL effects into immune cell subpopulations
R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ...
BMC Bioinformatics 21 (1), 1-23, 2020
Prolonged re-expression of the hypermethylated gene EPB41L3 using artificial transcription factors and epigenetic drugs
C Huisman, MGP van der Wijst, F Falahi, J Overkamp, G Karsten, ...
Epigenetics 10 (5), 384-396, 2015
Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py
A Geersing, N Ségaud, MGP van der Wijst, MG Rots, G Roelfes
Inorganic Chemistry 57 (13), 7748-7756, 2018
Efficient nuclear DNA cleavage in human cancer cells by synthetic bleomycin mimics
Q Li, MGP van der Wijst, HG Kazemier, MG Rots, G Roelfes
ACS chemical biology 9 (4), 1044-1051, 2014
Re-expression of selected epigenetically silenced candidate tumor suppressor genes in cervical cancer by TET2-directed demethylation
C Huisman, MGP Van Der Wijst, M Schokker, P Blancafort, MM Terpstra, ...
Molecular Therapy 24 (3), 536-547, 2016
Targeting Nrf2 in healthy and malignant ovarian epithelial cells: Protection versus promotion
MGP van der Wijst, C Huisman, A Mposhi, G Roelfes, MG Rots
Molecular oncology 9 (7), 1259-1273, 2015
Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response
DH de Vries, V Matzaraki, OB Bakker, H Brugge, HJ Westra, MG Netea, ...
PLoS Pathogens 16 (4), e1008408, 2020
Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure
R Oelen, DH de Vries, H Brugge, MG Gordon, M Vochteloo, CJ Ye, ...
Nature Communications 13 (1), 1-15, 2022
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data
S Li, KT Schmid, D de Vries, M Korshevniuk, R Oelen, I van Blokland, ...
bioRxiv, 2022
Translational insights from single-cell technologies across the cardiovascular disease continuum
IV van Blokland, HE Groot, LH Franke, MGP van der Wijst, P van der Harst
Trends in Cardiovascular Medicine, 2021
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