| Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 1155* | 2021 |
| Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs MGP van der Wijst, H Brugge, DH de Vries, P Deelen, MA Swertz, L study, ... Nature Genetics, 2018 | 313 | 2018 |
| Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19 MGP van der Wijst, SE Vazquez, GC Hartoularos, P Bastard, T Grant, ... Science translational medicine 13 (612), eabh2624, 2021 | 191* | 2021 |
| The single-cell eQTLGen consortium MGP van der Wijst, DH de Vries, HE Groot, G Trynka, CC Hon, MJ Bonder, ... elife 9, e52155, 2020 | 160 | 2020 |
| Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase MGP van der Wijst, M Venkiteswaran, H Chen, GL Xu, T Plösch, MG Rots Epigenetics 10 (8), 671-676, 2015 | 103 | 2015 |
| Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression MGP van der Wijst, AY van Tilburg, MHJ Ruiters, MG Rots Scientific reports 7 (1), 177, 2017 | 102 | 2017 |
| Mitochondrial epigenetics: an overlooked layer of regulation? MGP van der Wijst, MG Rots Trends in Genetics 31 (7), 353-356, 2015 | 98 | 2015 |
| Regulation of mitochondrial gene expression, the epigenetic enigma A Mposhi, MG Van der Wijst, KN Faber, MG Rots Front Biosci (Landmark Ed) 22 (7), 1099-113, 2017 | 90 | 2017 |
| An integrative approach for building personalized gene regulatory networks for precision medicine MGP Van Der Wijst, DH de Vries, H Brugge, HJ Westra, L Franke Genome medicine 10, 1-15, 2018 | 83 | 2018 |
| Nrf2, the master redox switch: the Achilles' heel of ovarian cancer? MGP van der Wijst, R Brown, MG Rots Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (2), 494-509, 2014 | 65 | 2014 |
| Deconvolution of bulk blood eQTL effects into immune cell subpopulations R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ... BMC bioinformatics 21, 1-23, 2020 | 47 | 2020 |
| Re-expression of selected epigenetically silenced candidate tumor suppressor genes in cervical cancer by TET2-directed demethylation C Huisman, MGP Van Der Wijst, M Schokker, P Blancafort, MM Terpstra, ... Molecular Therapy 24 (3), 536-547, 2016 | 44 | 2016 |
| Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure R Oelen, DH de Vries, H Brugge, MG Gordon, M Vochteloo, ... Nature Communications 13 (1), 3267, 2022 | 40* | 2022 |
| Prolonged re-expression of the hypermethylated gene EPB41L3 using artificial transcription factors and epigenetic drugs C Huisman, MGP van der Wijst, F Falahi, J Overkamp, G Karsten, ... Epigenetics 10 (5), 384-396, 2015 | 35 | 2015 |
| Efficient nuclear DNA cleavage in human cancer cells by synthetic bleomycin mimics Q Li, MGP van der Wijst, HG Kazemier, MG Rots, G Roelfes ACS chemical biology 9 (4), 1044-1051, 2014 | 34 | 2014 |
| Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py A Geersing, N Ségaud, MGP van der Wijst, MG Rots, G Roelfes Inorganic Chemistry 57 (13), 7748-7756, 2018 | 33 | 2018 |
| Targeting Nrf2 in healthy and malignant ovarian epithelial cells: Protection versus promotion MGP van der Wijst, C Huisman, A Mposhi, G Roelfes, MG Rots Molecular oncology 9 (7), 1259-1273, 2015 | 28 | 2015 |
| Genetic, parental and lifestyle factors influence telomere length S Andreu-Sánchez, G Aubert, A Ripoll-Cladellas, S Henkelman, ... Communications biology 5 (1), 565, 2022 | 24 | 2022 |
| Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response DH de Vries, V Matzaraki, OB Bakker, H Brugge, HJ Westra, MG Netea, ... PLoS Pathogens 16 (4), e1008408, 2020 | 23 | 2020 |
| Gut mucosa dissociation protocols influence cell type proportions and single-cell gene expression levels WTC Uniken Venema, AD Ramírez-Sánchez, E Bigaeva, S Withoff, ... Scientific Reports 12 (1), 9897, 2022 | 22 | 2022 |
Lude FrankeProfessor of Functional Genomics, University Medical Centre GroningenVerified email at cleverfranke.com
