Wouter W Wiegant
Wouter W Wiegant
Research Technician at The Haico van Attikum Research group, LUMC, the Netherlands
Geverifieerd e-mailadres voor lumc.nl
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The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J
M Levitus, Q Waisfisz, BC Godthelp, Y Vries, S Hussain, WW Wiegant, ...
Nature genetics 37 (9), 934-935, 2005
A DNA-PKcs mutation in a radiosensitive TB SCID patient inhibits Artemis activation and nonhomologous end-joining
M Van Der Burg, H IJspeert, NS Verkaik, T Turul, WW Wiegant, ...
The Journal of clinical investigation 119 (1), 91-98, 2009
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection
T Costelloe, R Louge, N Tomimatsu, B Mukherjee, E Martini, B Khadaroo, ...
Nature 489 (7417), 581-584, 2012
The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage
G Smeenk, WW Wiegant, H Vrolijk, AP Solari, A Pastink, H van Attikum
Journal of Cell Biology 190 (5), 741-749, 2010
A new type of radiosensitive TBNK+ severe combined immunodeficiency caused by a LIG4 mutation
M van der Burg, LR van Veelen, NS Verkaik, WW Wiegant, NG Hartwig, ...
The Journal of clinical investigation 116 (1), 137-145, 2006
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality
E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ...
Cancer cell 33 (6), 1078-1093. e12, 2018
Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability
BC Godthelp, WW Wiegant, A van Duijn-Goedhart, OD Schärer, ...
Nucleic acids research 30 (10), 2172-2182, 2002
Poly (ADP-ribosyl) ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling
G Smeenk, WW Wiegant, JA Marteijn, MS Luijsterburg, N Sroczynski, ...
Journal of cell science 126 (4), 889-903, 2013
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre–B-cell receptor checkpoint in bone marrow
JG Noordzij, NS Verkaik, M Van Der Burg, LR Van Veelen, ...
Blood, The Journal of the American Society of Hematology 101 (4), 1446-1452, 2003
A new non‐catalytic role for ubiquitin ligase RNF8 in unfolding higher‐order chromatin structure
MS Luijsterburg, K Acs, L Ackermann, WW Wiegant, S Bekker‐Jensen, ...
The EMBO journal 31 (11), 2511-2527, 2012
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions
H Saeki, N Siaud, N Christ, WW Wiegant, PPW Van Buul, M Han, ...
Proceedings of the National Academy of Sciences 103 (23), 8768-8773, 2006
ZMYND8 co-localizes with NuRD on target genes and regulates poly (ADP-ribose)-dependent recruitment of GATAD2A/NuRD to sites of DNA damage
CG Spruijt, MS Luijsterburg, R Menafra, RGH Lindeboom, PWTC Jansen, ...
Cell reports 17 (3), 783-798, 2016
Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2
BC Godthelp, WW Wiegant, Q Waisfisz, AL Medhurst, F Arwert, H Joenje, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 594 (1 …, 2006
The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80
D Typas, MS Luijsterburg, WW Wiegant, M Diakatou, A Helfricht, ...
Nucleic acids research 43 (14), 6919-6933, 2015
A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation
MS Luijsterburg, D Typas, MC Caron, WW Wiegant, D van den Heuvel, ...
Elife 6, e20922, 2017
Ataxin‐3 consolidates the MDC 1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF 4
A Pfeiffer, MS Luijsterburg, K Acs, WW Wiegant, A Helfricht, LK Herzog, ...
The EMBO journal 36 (8), 1066-1083, 2017
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle
F Darroudi, W Wiegant, M Meijers, AA Friedl, M van der Burg, J Fomina, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 615 (1 …, 2007
WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks
P Caron, T Pankotai, WW Wiegant, MAX Tollenaere, A Furst, ...
Genes & development 33 (11-12), 684-704, 2019
Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining
H Helfricht,A., Wiegant,W.W., Thijssen,P.E
Cell Cycle 12 (16), 2013
Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function
WW Wiegant, RM Overmeer, BC Godthelp, PPW van Buul, MZ Zdzienicka
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 600 (1 …, 2006
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