| Heightened cold-denaturation of proteins at the ice–water interface A Arsiccio, J McCarty, R Pisano, JE Shea Journal of the American Chemical Society 142 (12), 5722-5730, 2020 | 71 | 2020 |
| The ice-water interface and protein stability: A review A Arsiccio, R Pisano Journal of Pharmaceutical Sciences 109 (7), 2116-2130, 2020 | 69 | 2020 |
| Achieving continuous manufacturing in lyophilization: Technologies and approaches R Pisano, A Arsiccio, LC Capozzi, BL Trout European Journal of Pharmaceutics and Biopharmaceutics 142, 265-279, 2019 | 66 | 2019 |
| Prediction of ice crystal size distribution after freezing of pharmaceutical solutions A Arsiccio, AA Barresi, R Pisano Crystal Growth & Design 17 (9), 4573-4581, 2017 | 51 | 2017 |
| Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach A Arsiccio, P Giorsello, L Marenco, R Pisano Journal of Pharmaceutical Sciences 109 (1), 464-475, 2020 | 47 | 2020 |
| Stability of proteins in carbohydrates and other additives during freezing: the human growth hormone as a case study A Arsiccio, R Pisano The Journal of Physical Chemistry B 121 (37), 8652-8660, 2017 | 43 | 2017 |
| Application of the quality by design approach to the freezing step of freeze-drying: building the design space A Arsiccio, R Pisano Journal of Pharmaceutical Sciences 107 (6), 1586-1596, 2018 | 42 | 2018 |
| Effect of surfactants on surface-induced denaturation of proteins: evidence of an orientation-dependent mechanism A Arsiccio, J McCarty, R Pisano, JE Shea The Journal of Physical Chemistry B 122 (49), 11390-11399, 2018 | 39 | 2018 |
| Tuning, measurement and prediction of the impact of freezing on product morphology: A step toward improved design of freeze-drying cycles R Pisano, A Arsiccio, K Nakagawa, AA Barresi Drying technology 37 (5), 579-599, 2019 | 33 | 2019 |
| Vacuum Induced Surface Freezing as an effective method for improved inter-and intra-vial product homogeneity A Arsiccio, A Barresi, T De Beer, I Oddone, PJ Van Bockstal, R Pisano European Journal of Pharmaceutics and Biopharmaceutics 128, 210-219, 2018 | 33 | 2018 |
| Measuring and predicting pore size distribution of freeze-dried solutions A Arsiccio, AC Sparavigna, R Pisano, AA Barresi Drying technology 37 (4), 435-447, 2019 | 30 | 2019 |
| Surfactants as stabilizers for biopharmaceuticals: an insight into the molecular mechanisms for inhibition of protein aggregation A Arsiccio, R Pisano European Journal of Pharmaceutics and Biopharmaceutics 128, 98-106, 2018 | 28 | 2018 |
| Water entrapment and structure ordering as protection mechanisms for protein structural preservation A Arsiccio, R Pisano The Journal of Chemical Physics 148 (5), 2018 | 27 | 2018 |
| Designing the optimal formulation for biopharmaceuticals: a new approach combining molecular dynamics and experiments A Arsiccio, A Paladini, F Pattarino, R Pisano Journal of Pharmaceutical Sciences 108 (1), 431-438, 2019 | 24 | 2019 |
| Clarifying the role of cryo-and lyo-protectants in the biopreservation of proteins A Arsiccio, R Pisano Physical Chemistry Chemical Physics 20 (12), 8267-8277, 2018 | 24 | 2018 |
| Vacuum-induced surface freezing for the freeze-drying of the human growth hormone: how does nucleation control affect protein stability? I Oddone, A Arsiccio, C Duru, K Malik, J Ferguson, R Pisano, ... Journal of Pharmaceutical Sciences 109 (1), 254-263, 2020 | 23 | 2020 |
| The role of cyclodextrins against interface-induced denaturation in pharmaceutical formulations: A molecular dynamics approach M Rospiccio, A Arsiccio, G Winter, R Pisano Molecular Pharmaceutics 18 (6), 2322-2333, 2021 | 22 | 2021 |
| Terminal capping of an amyloidogenic tau fragment modulates its fibrillation propensity S Arya, P Ganguly, A Arsiccio, SL Claud, B Trapp, GE Schonfeld, X Liu, ... The Journal of Physical Chemistry B 124 (40), 8772-8783, 2020 | 18 | 2020 |
| ADD Force Field for Sugars and Polyols: Predicting the Additivity of Protein–Osmolyte Interaction A Arsiccio, P Ganguly, L La Cortiglia, JE Shea, R Pisano The Journal of Physical Chemistry B 124 (36), 7779-7790, 2020 | 15 | 2020 |
| Pressure unfolding of proteins: New insights into the role of bound water A Arsiccio, JE Shea The Journal of Physical Chemistry B 125 (30), 8431-8442, 2021 | 13 | 2021 |
