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Tineke Lenstra
Tineke Lenstra
Netherlands Cancer Institute, Oncode Institute
Geverifieerd e-mailadres voor lenstralab.nl - Homepage
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Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors
P Kemmeren, K Sameith, LAL Van De Pasch, JJ Benschop, TL Lenstra, ...
Cell 157 (3), 740-752, 2014
3192014
The specificity and topology of chromatin interaction pathways in yeast
TL Lenstra, JJ Benschop, TS Kim, JM Schulze, NACH Brabers, ...
Molecular cell 42 (4), 536-549, 2011
2562011
Transcription dynamics in living cells
TL Lenstra, J Rodriguez, H Chen, DR Larson
Annual review of biophysics 45, 25-47, 2016
1752016
Live‐cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting
BT Donovan, A Huynh, DA Ball, HP Patel, MG Poirier, DR Larson, ...
The EMBO journal 38 (12), e100809, 2019
1592019
Functional overlap and regulatory links shape genetic interactions between signaling pathways
S van Wageningen, P Kemmeren, P Lijnzaad, T Margaritis, JJ Benschop, ...
Cell 143 (6), 991-1004, 2010
1472010
Single-molecule imaging reveals a switch between spurious and functional ncRNA transcription
TL Lenstra, A Coulon, CC Chow, DR Larson
Molecular cell 60 (4), 597-610, 2015
1202015
Cell cycle population effects in perturbation studies
E O'Duibhir, P Lijnzaad, JJ Benschop, TL Lenstra, D van Leenen, ...
Molecular systems biology 10 (6), 732, 2014
1132014
Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs
MC Daugeron, TL Lenstra, M Frizzarin, B El Yacoubi, X Liu, ...
Nucleic acids research 39 (14), 6148-6160, 2011
952011
Visualizing transcription: key to understanding gene expression dynamics
I Brouwer, TL Lenstra
Current opinion in chemical biology 51, 122-129, 2019
602019
Dysregulated RasGRP1 responds to cytokine receptor input in T cell leukemogenesis
C Hartzell, O Ksionda, E Lemmens, K Coakley, M Yang, M Dail, ...
Science signaling 6 (268), ra21-ra21, 2013
552013
Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation
JE Haber, H Braberg, Q Wu, R Alexander, J Haase, C Ryan, ...
Cell reports 3 (6), 2168-2178, 2013
492013
RNA Pol II length and disorder enable cooperative scaling of transcriptional bursting
P Quintero-Cadena, TL Lenstra, PW Sternberg
Molecular cell 79 (2), 207-220. e8, 2020
442020
Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism
T van Welsem, T Korthout, R Ekkebus, D Morais, TM Molenaar, ...
Nucleic acids research 46 (21), 11251-11261, 2018
352018
A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover
KF Verzijlbergen, T van Welsem, D Sie, TL Lenstra, DJ Turner, ...
PLoS genetics 7 (10), e1002284, 2011
342011
Dot1 binding induces chromatin rearrangements by histone methylation-dependent and-independent mechanisms
IJE Stulemeijer, BL Pike, AW Faber, KF Verzijlbergen, T van Welsem, ...
Epigenetics & chromatin 4, 1-14, 2011
332011
Quantifying how post-transcriptional noise and gene copy number variation bias transcriptional parameter inference from mRNA distributions
X Fu, HP Patel, S Coppola, L Xu, Z Cao, TL Lenstra, R Grima
Elife 11, e82493, 2022
292022
Single‐molecule mRNA detection in live yeast
TL Lenstra, DR Larson
Current protocols in molecular biology 113 (1), 14.24. 1-14.24. 15, 2016
292016
Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast
TM Ng, TL Lenstra, N Duggan, S Jiang, S Ceto, FCP Holstege, J Dai, ...
Genetics 195 (3), 795-807, 2013
262013
The role of Ctk1 kinase in termination of small non-coding RNAs
TL Lenstra, A Tudek, S Clauder, Z Xu, ST Pachis, D van Leenen, ...
PLoS One 8 (12), e80495, 2013
242013
The discrepancy between chromatin factor location and effect
TL Lenstra, FCP Holstege
Nucleus 3 (3), 213-219, 2012
242012
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Artikelen 1–20