Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells JM Polo, S Liu, ME Figueroa, W Kulalert, S Eminli, KY Tan, E Apostolou, ... Nature biotechnology 28 (8), 848-855, 2010 | 1407 | 2010 |
A molecular roadmap of reprogramming somatic cells into iPS cells JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ... Cell 151 (7), 1617-1632, 2012 | 986 | 2012 |
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells M Stadtfeld, E Apostolou, H Akutsu, A Fukuda, P Follett, S Natesan, ... Nature 465 (7295), 175-181, 2010 | 891 | 2010 |
Chromatin dynamics during cellular reprogramming E Apostolou, K Hochedlinger Nature 502 (7472), 462-471, 2013 | 441 | 2013 |
Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all–iPS cell mice from terminally differentiated B cells M Stadtfeld, E Apostolou, F Ferrari, J Choi, RM Walsh, T Chen, SSK Ooi, ... Nature genetics 44 (4), 398-405, 2012 | 319 | 2012 |
Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system SM Buckley, B Aranda-Orgilles, A Strikoudis, E Apostolou, E Loizou, ... Cell stem cell 11 (6), 783-798, 2012 | 288 | 2012 |
Virus infection induces NF-κB-dependent interchromosomal associations mediating monoallelic IFN-β gene expression E Apostolou, D Thanos Cell 134 (1), 85-96, 2008 | 280 | 2008 |
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming E Apostolou, F Ferrari, RM Walsh, O Bar-Nur, M Stadtfeld, S Cheloufi, ... Cell stem cell 12 (6), 699-712, 2013 | 224 | 2013 |
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture N Yusufova, A Kloetgen, M Teater, A Osunsade, JM Camarillo, CR Chin, ... Nature 589 (7841), 299-305, 2021 | 181 | 2021 |
The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development J Qin, WA Whyte, E Anderssen, E Apostolou, HH Chen, S Akbarian, ... Cell stem cell 11 (3), 319-332, 2012 | 150 | 2012 |
Widespread mitotic bookmarking by histone marks and transcription factors in pluripotent stem cells Y Liu, B Pelham-Webb, DC Di Giammartino, J Li, D Kim, K Kita, N Saiz, ... Cell reports 19 (7), 1283-1293, 2017 | 134 | 2017 |
Small molecules facilitate rapid and synchronous iPSC generation O Bar-Nur, J Brumbaugh, C Verheul, E Apostolou, I Pruteanu-Malinici, ... Nature methods 11 (11), 1170-1176, 2014 | 133 | 2014 |
KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks DC Di Giammartino, A Kloetgen, A Polyzos, Y Liu, D Kim, D Murphy, ... Nature cell biology 21 (10), 1179-1190, 2019 | 131 | 2019 |
Local genome topology can exhibit an incompletely rewired 3D-folding state during somatic cell reprogramming JA Beagan, TG Gilgenast, J Kim, Z Plona, HK Norton, G Hu, SC Hsu, ... Cell stem cell 18 (5), 611-624, 2016 | 124 | 2016 |
PRC2 is required to maintain expression of the maternal Gtl2-Rian-Mirg locus by preventing de novo DNA methylation in mouse embryonic stem cells PP Das, DA Hendrix, E Apostolou, AH Buchner, MC Canver, S Beyaz, ... Cell reports 12 (9), 1456-1470, 2015 | 73 | 2015 |
Identification of cancer drivers at CTCF insulators in 1,962 whole genomes EM Liu, A Martinez-Fundichely, BJ Diaz, B Aronson, T Cuykendall, ... Cell systems 8 (5), 446-455. e8, 2019 | 67 | 2019 |
Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements A Antonaki, C Demetriades, A Polyzos, A Banos, G Vatsellas, MD Lavigne, ... Journal of Biological Chemistry 286 (44), 38768-38782, 2011 | 67 | 2011 |
A serial shRNA screen for roadblocks to reprogramming identifies the protein modifier SUMO2 M Borkent, BD Bennett, B Lackford, O Bar-Nur, J Brumbaugh, L Wang, ... Stem cell reports 6 (5), 704-716, 2016 | 64 | 2016 |
H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization B Pelham-Webb, A Polyzos, L Wojenski, A Kloetgen, J Li, ... Molecular cell 81 (8), 1732-1748. e8, 2021 | 63 | 2021 |
Cellular trajectories and molecular mechanisms of iPSC reprogramming E Apostolou, M Stadtfeld Current opinion in genetics & development 52, 77-85, 2018 | 54 | 2018 |