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Shriram M. Pathak
Shriram M. Pathak
Eisai, United Kingdom
Geverifieerd e-mailadres voor eisai.net
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Model-Based Analysis of Biopharmaceutic Experiments To Improve Mechanistic Oral Absorption Modeling: An Integrated in Vitro in Vivo Extrapolation Perspective …
SM Pathak, A Ruff, ES Kostewicz, N Patel, DB Turner, M Jamei
Molecular pharmaceutics 14 (12), 4305-4320, 2017
822017
In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole
B Hens, SM Pathak, A Mitra, N Patel, B Liu, S Patel, M Jamei, J Brouwers, ...
Molecular pharmaceutics 14 (12), 4321-4333, 2017
712017
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
A Margolskee, AS Darwich, X Pepin, L Aarons, A Galetin, ...
European Journal of Pharmaceutical Sciences 96, 610-625, 2017
642017
Enhanced oral absorption of saquinavir with methyl-beta-cyclodextrin—preparation and in vitro and in vivo evaluation
SM Pathak, P Musmade, S Dengle, A Karthik, K Bhat, N Udupa
European journal of pharmaceutical sciences 41 (3-4), 440-451, 2010
572010
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across …
AS Darwich, A Margolskee, X Pepin, L Aarons, A Galetin, ...
European Journal of Pharmaceutical Sciences 96, 626-642, 2017
462017
IMI–oral biopharmaceutics tools project–evaluation of bottom-up PBPK prediction success part 1: characterisation of the OrBiTo database of compounds
A Margolskee, AS Darwich, X Pepin, SM Pathak, MB Bolger, L Aarons, ...
European Journal of Pharmaceutical Sciences 96, 598-609, 2017
422017
Biopharmaceutic IVIVE—mechanistic modeling of single-and two-phase in vitro experiments to obtain drug-specific parameters for incorporation into PBPK models
SM Pathak, KJ Schaefer, M Jamei, DB Turner
Journal of pharmaceutical sciences 108 (4), 1604-1618, 2019
412019
Evaluation of chemical interactions of maleic acid with sodium hypochlorite and chlorhexidine gluconate
NV Ballal, S Moorkoth, K Mala, KS Bhat, SS Hussen, S Pathak
Journal of endodontics 37 (10), 1402-1405, 2011
392011
A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma—application to preclinical …
SM Pathak, AR Kumar, P Musmade, N Udupa
Talanta 76 (2), 338-346, 2008
392008
The regional-specific relative and absolute expression of gut transporters in adult caucasians: a meta-analysis
MD Harwood, M Zhang, SM Pathak, S Neuhoff
Drug Metabolism and Disposition 47 (8), 854-864, 2019
362019
Best practices in the development and validation of physiologically based biopharmaceutics modeling. A workshop summary report
N Parrott, S Suarez-Sharp, F Kesisoglou, SM Pathak, D Good, C Wagner, ...
Journal of Pharmaceutical Sciences 110 (2), 584-593, 2021
282021
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling …
A Ahmad, X Pepin, L Aarons, Y Wang, AS Darwich, JM Wood, ...
European Journal of Pharmaceutics and Biopharmaceutics 156, 50-63, 2020
252020
Critical attributes of transdermal drug delivery system (TDDS)–a generic product development review
PK Ruby, SM Pathak, D Aggarwal
Drug development and industrial pharmacy 40 (11), 1421-1428, 2014
232014
Pre‐clinical evidence of enhanced oral bioavailability of the P‐glycoprotein substrate talinolol in combination with morin
SM Pathak, N Udupa
Biopharmaceutics & Drug Disposition 31 (2‐3), 202-214, 2010
232010
Practical and operational considerations related to paediatric oral drug formulation: An industry survey
M Van der Veken, J Brouwers, V Budts, L Lauwerys, SM Pathak, ...
International journal of pharmaceutics 618, 121670, 2022
172022
Development and validation of a reversed-phase liquid chromatographic method with fluorescence detection for the study of Saquinavir pharmacokinetics in rat plasma
SM Pathak, AR Kumar, G Subramanian, N Udupa
Analytica chimica acta 594 (2), 248-256, 2007
162007
Novel liquid chromatographic method for simultaneous estimation of pioglitazone and glimepiride in rat plasma by solid phase extraction: application to preclinical …
PB Musmade, KB Talole, PB Deshpande, A Karthik, SM Pathak, S Pandey, ...
Arzneimittelforschung 61 (01), 23-31, 2011
112011
High Performance Liquid Chromatographic Method for the Determination of Clobetasol in Rat Plasma and its Application to Skin Penetration
PB Musmade, PB Deshpande, SJ Dengle, KB Talole, SM Pathak, ...
Journal of Bioanalysis & Biomedicine 2, 2010
112010
Stability-indicating HPTLC determination of capsaicin in the bulk drug
G Subramanian, A Karthik, S Kamath, K Prabahar, A Ranjithkumar, ...
JPC-Journal of Planar Chromatography-Modern TLC 21 (4), 271-275, 2008
112008
Population-based PBPK model for the prediction of time-variant bile salt disposition within GI luminal fluids
K Stamatopoulos, SM Pathak, L Marciani, DB Turner
Molecular Pharmaceutics 17 (4), 1310-1323, 2020
102020
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Artikelen 1–20