| Direct interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response W Chen, Z Sun, XJ Wang, T Jiang, Z Huang, D Fang, DD Zhang Molecular cell 34 (6), 663-673, 2009 | 696 | 2009 |
| Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy H Zheng, SA Whitman, W Wu, GT Wondrak, PK Wong, D Fang, DD Zhang Diabetes 60 (11), 3055-3066, 2011 | 558 | 2011 |
| The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy T Jiang, Z Huang, Y Lin, Z Zhang, D Fang, DD Zhang Diabetes 59 (4), 850-860, 2010 | 490 | 2010 |
| Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch M Gao, T Labuda, Y Xia, E Gallagher, D Fang, YC Liu, M Karin Science 306 (5694), 271-275, 2004 | 487 | 2004 |
| Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase L Qiu, C Joazeiro, N Fang, HY Wang, C Elly, Y Altman, D Fang, T Hunter, ... Journal of Biological Chemistry 275 (46), 35734-35737, 2000 | 435 | 2000 |
| Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation D Fang, C Elly, B Gao, N Fang, Y Altman, C Joazeiro, T Hunter, ... Nature immunology 3 (3), 281-287, 2002 | 417 | 2002 |
| Proteolysis-independent regulation of PI3K by Cbl-b–mediated ubiquitination in T cells D Fang, YC Liu Nature immunology 2 (9), 870-875, 2001 | 338 | 2001 |
| Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis T Wu, F Zhao, B Gao, C Tan, N Yagishita, T Nakajima, PK Wong, ... Genes & development 28 (7), 708-722, 2014 | 327 | 2014 |
| USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development Z Lin, H Yang, Q Kong, J Li, SM Lee, B Gao, H Dong, J Wei, J Song, ... Molecular cell 46 (4), 484-494, 2012 | 313 | 2012 |
| The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice J Zhang, SM Lee, S Shannon, B Gao, W Chen, A Chen, R Divekar, ... The Journal of clinical investigation 119 (10), 3048-3058, 2009 | 307 | 2009 |
| The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch A Traweger, D Fang, YC Liu, W Stelzhammer, IA Krizbai, F Fresser, ... Journal of Biological Chemistry 277 (12), 10201-10208, 2002 | 242 | 2002 |
| Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells D Fang, HY Wang, N Fang, Y Altman, C Elly, YC Liu Journal of Biological Chemistry 276 (7), 4872-4878, 2001 | 241 | 2001 |
| The roles of SIRT1 in cancer Z Lin, D Fang Genes & cancer 4 (3-4), 97-104, 2013 | 240 | 2013 |
| USP10 antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formation Z Lin, H Yang, C Tan, J Li, Z Liu, Q Quan, S Kong, J Ye, B Gao, D Fang Cell reports 5 (6), 1639-1649, 2013 | 208 | 2013 |
| Toll‐like receptor‐mediated IRE1α activation as a therapeutic target for inflammatory arthritis Q Qiu, Z Zheng, L Chang, YS Zhao, C Tan, A Dandekar, Z Zhang, Z Lin, ... The EMBO journal 32 (18), 2477-2490, 2013 | 204 | 2013 |
| IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation S Sun, G Shi, H Sha, Y Ji, X Han, X Shu, H Ma, T Inoue, B Gao, H Kim, ... Nature cell biology 17 (12), 1546-1555, 2015 | 199 | 2015 |
| Cbl promotes ubiquitination of the T cell receptor ζ through an adaptor function of Zap-70 HY Wang, Y Altman, D Fang, C Elly, Y Dai, Y Shao, YC Liu Journal of Biological Chemistry 276 (28), 26004-26011, 2001 | 199 | 2001 |
| TGFβ signaling in the pancreatic tumor microenvironment promotes fibrosis and immune evasion to facilitate tumorigenesis DR Principe, B DeCant, E Mascariñas, EA Wayne, AM Diaz, N Akagi, ... Cancer research 76 (9), 2525-2539, 2016 | 193 | 2016 |
| Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes SM Lee, H Yang, DM Tartar, B Gao, X Luo, SQ Ye, H Zaghouani, D Fang Diabetologia 54, 1136-1146, 2011 | 168 | 2011 |
| Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes D Fang, TK Kerppola Proceedings of the National Academy of Sciences 101 (41), 14782-14787, 2004 | 164 | 2004 |
