| Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response C Gorrini, M Squatrito, C Luise, N Syed, D Perna, L Wark, F Martinato, ... Nature 448 (7157), 1063-1067, 2007 | 382 | 2007 |
| Characterizing the three‐dimensional organization of telomeres BJ Vermolen, Y Garini, S Mai, V Mougey, T Fest, TCY Chuang, ... Cytometry Part A: the journal of the International Society for Analytical …, 2005 | 124 | 2005 |
| Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia T Rio Frio, J Lavoie, N Hamel, FC Geyer, YB Kushner, DJ Novak, L Wark, ... New England Journal of Medicine 363 (27), 2628-2637, 2010 | 106 | 2010 |
| Nuclear remodeling as a mechanism for genomic instability in cancer M Gadji, R Vallente, L Klewes, C Righolt, L Wark, N Kongruttanachok, ... Advances in cancer research 112, 77-126, 2011 | 31 | 2011 |
| Telomeric aggregates and end-to-end chromosomal fusions require myc box II A Caporali, L Wark, BJ Vermolen, Y Garini, S Mai Oncogene 26 (10), 1398-1406, 2007 | 27 | 2007 |
| Distinct 3D structural patterns of lamin A/C expression in Hodgkin and Reed-Sternberg cells F Contu, A Rangel-Pozzo, P Trokajlo, L Wark, L Klewes, NA Johnson, ... Cancers 10 (9), 286, 2018 | 25 | 2018 |
| High Mobility Group A2 protects cancer cells against telomere dysfunction S Natarajan, F Begum, J Gim, L Wark, D Henderson, JR Davie, ... Oncotarget 7 (11), 12761, 2016 | 22 | 2016 |
| Increased genomic instability and altered chromosomal protein phosphorylation timing in HRAS‐transformed mouse fibroblasts KL Dunn, S He, L Wark, GP Delcuve, JM Sun, H Yu Chen, S Mai, ... Genes, Chromosomes and Cancer 48 (5), 397-409, 2009 | 21 | 2009 |
| Nuclear imaging in three dimensions: a unique tool in cancer research T Klonisch, L Wark, S Hombach-Klonisch, S Mai Annals of Anatomy-Anatomischer Anzeiger 192 (5), 292-301, 2010 | 20 | 2010 |
| Premature aging is associated with higher levels of 8‐oxoguanine and increased DNA damage in the Polg mutator mouse T Yu, J Slone, W Liu, R Barnes, PL Opresko, L Wark, S Mai, S Horvath, ... Aging Cell 21 (9), e13669, 2022 | 16 | 2022 |
| Heterozygous mutations in the PALB2 hereditary breast cancer predisposition gene impact on the three‐dimensional nuclear organization of patient‐derived cell … L Wark, D Novak, N Sabbaghian, L Amrein, JR Jangamreddy, M Cheang, ... Genes, Chromosomes and Cancer 52 (5), 480-494, 2013 | 15 | 2013 |
| Nucleosomal response, immediate-early gene expression and cell transformation JR Davie, B Drobic, B Perez-Cadahia, S He, PS Espino, JM Sun, ... Advances in Enzyme Regulation 50 (1), 135-145, 2010 | 14 | 2010 |
| Long-term dynamics of three dimensional telomere profiles in circulating tumor cells in high-risk prostate cancer patients undergoing androgen-deprivation and radiation therapy L Wark, H Quon, A Ong, D Drachenberg, A Rangel-Pozzo, S Mai Cancers 11 (8), 1165, 2019 | 11 | 2019 |
| Dynamics of three-dimensional telomere profiles of circulating tumor cells in patients with high-risk prostate cancer who are undergoing androgen deprivation and radiation … L Wark, T Klonisch, J Awe, C LeClerc, B Dyck, H Quon, S Mai Urologic Oncology: Seminars and Original Investigations 35 (3), 112. e1-112. e11, 2017 | 10 | 2017 |
| Three-dimensional telomere dynamics in follicular thyroid cancer L Wark, A Danescu, S Natarajan, X Zhu, S Cheng, S Hombach-Klonisch, ... Thyroid 24 (2), 296-304, 2014 | 10 | 2014 |
| Three-dimensional analysis tool for segmenting and measuring the structure of telomeres in mammalian nuclei BJ Vermolen, IT Young, A Chuang, L Wark, T Chuang, S Mai, Y Garini Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals …, 2005 | 2 | 2005 |
| Three dimensional telomeric profiles in circulating tumour cells as a method of monitoring treatment response in high-risk prostate cancer patients L Wark | | 2016 |
| Three Dimensional Telomeric Profiles in Circulating Tumor Cells of High-Risk Prostate Cancer Patients Undergoing Androgen Deprivation and Radiation Therapy L Wark, HC Quon, A Ong, S Ahmed, R Koul, A Chowdhury, S Mai International Journal of Radiation Oncology, Biology, Physics 93 (3), S103-S104, 2015 | | 2015 |
| Nuclear architecture in human thyroid carcinoma revealed by three-dimensional (3D) telomere imaging: New insight into genomic instability and potential diagnostic application T Klonisch, L Wark, S Hombach-Klonisch, C Hoang-Vu, S Cheng, S Mai CANCER RESEARCH 69, 2009 | | 2009 |
| Abstract# 469: Nuclear architecture in human thyroid carcinoma revealed by three-dimensional (3D) telomere imaging: New insight into genomic instability and potential … T Klonisch, L Wark, S Hombach-Klonisch, C Hoang-Vu, S Cheng, S Mai Cancer Research 69 (9_Supplement), 469-469, 2009 | | 2009 |
