Sheryl M Gough
Sheryl M Gough
Arvinas LLC
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NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights
SM Gough, CI Slape, PD Aplan
Blood 118 (24), 6247-6257, 2011
Age-related epigenetic drift in the pathogenesis of MDS and AML
S Maegawa, SM Gough, N Watanabe-Okochi, Y Lu, N Zhang, RJ Castoro, ...
Genome research 24 (4), 580-591, 2014
NUP98–PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to Inhibition of PHD Histone Reader Function
SM Gough, F Lee, F Yang, RL Walker, YJ Zhu, M Pineda, M Onozawa, ...
Cancer discovery 4 (5), 564-577, 2014
Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome
YJ Chung, C Robert, SM Gough, FV Rassool, PD Aplan
Leukemia research 38 (1), 95-102, 2014
Cloning and characterization of a novel β integrin-related cDNA coding for the protein TIED (“ten β integrin EGF-like repeat domains”) that maps to chromosome band 13q33: a …
RW Berg, E Leung, S Gough, C Morris, WP Yao, SX Wang, J Ni, ...
Genomics 56 (2), 169-178, 1999
Cloning, sequence analysis, and chromosomal localization of the novel human integrin α11 subunit (ITGA11)
K Lehnert, J Ni, E Leung, SM Gough, A Weaver, WP Yao, D Liu, SX Wang, ...
Genomics 60 (2), 179-187, 1999
The small GTPase RAC3 gene is located within chromosome band 17q25. 3 outside and telomeric of a region commonly deleted in breast and ovarian tumours
CM Morris, L Haataja, M McDonald, S Gough, D Markie, J Groffen, ...
Cytogenetic and Genome Research 89 (1-2), 18-23, 2000
Release and clinical significance of soluble CD83 in chronic lymphocytic leukemia
BD Hock, LJ Fernyhough, SM Gough, A Steinkasserer, AG Cox, ...
Leukemia research 33 (8), 1089-1095, 2009
The integrin α10 subunit: expression pattern, partial gene structure, and chromosomal localization
K Lehnert, J Ni, E Leung, S Gough, CM Morris, D Liu, SX Wang, ...
Cytogenetic and Genome Research 87 (3-4), 238-244, 1999
Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect
SM Gough, YJ Chung, PD Aplan
PloS one 7 (5), e36876, 2012
Refined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13. 3-q21. 1
SM Gough, M McDonald, XN Chen, JR Korenberg, A Neri, T Kahn, ...
BMC genomics 4 (1), 9, 2003
Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance
L Goldberg, SM Gough, F Lee, C Dang, RL Walker, YJ Zhu, S Bilke, ...
Genes, Chromosomes and Cancer 56 (6), 472-483, 2017
Translocation (5; 10)(q22; q24) in a case of acute lymphoblastic leukemia
SM Gough, SM Benjes, M McDonald, D Heaton, P Ganly, CM Morris
Cancer genetics and cytogenetics 165 (1), 36-40, 2006
Clinical significance of plasma levels of soluble CD40 in patients with chronic lymphocytic leukemia
BD Hock, LJ Fernyhough, SM Gough, JL McKenzie
Open Journal of Blood Diseases 3 (01), 1, 2013
A NUP98-PHF23 Transgenic Mouse Model Develops AML and T-ALL
SM Gough, F Lee, YJ Chung, RL Walker, F Yang, YJ Zhu, Y Ning, ...
Blood 118 (21), 2467-2467, 2011
Hs. 568769 is disrupted by a novel t (5; 10) in acute lymphoblastic leukemia (ALL) and may be an alternate transcript of the 3'overlapping DNTT (TdT) gene
S Gough, A Aitchison, P Ganly, R Spearing, C Morris
Cancer Research 67 (9 Supplement), 357-357, 2007
IHC and flow cytometry quantifies BRD4 levels in surrogate tissues after ex-vivo and in-vivo dosing with a BRD4 degrading PROTAC
SM Gough, K Raina, D Gordon, R Willard, M Altieri, A Shen, Y Qian, ...
Cancer Research 77 (13 Supplement), 5076-5076, 2017
Spontaneous Mutations of Bcor and Jak1/2 genes Lead to an Aggressive Leukemia of B-1 Progenitor B Cells
SM Gough, L Goldberg, M Pineda, RL Walker, YJ Zhu, S Bilke, PS Meltzer, ...
Blood 124 (21), 3573-3573, 2014
Leukemia Driven By a NUP98-Phd Domain Fusion Is Highly Sensitive To Disruption Of H3K4me3-Phd Domain Binding By a Small Molecule Inhibitor
SM Gough, F Lee, RL Walker, F Yang, Y Zhu, M Pineda, M Onozawa, ...
Blood 122 (21), 3759-3759, 2013
NUP98-PHF23 (NP23) binds H3K4me3 and causes a wide spectrum of leukemias, including AML, T-ALL, and pre-B1 ALL.
SM Gough, F Lee, YJ Chung, RL Walker, F Yang, J Zhu, Y Ning, ...
Cancer Research 73 (8 Supplement), 3851-3851, 2013
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