| Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin MA Leissring, E Malito, S Hedouin, L Reinstatler, T Sahara, SO Abdul-Hay, ... PloS one 5 (5), e10504, 2010 | 132 | 2010 |
| Deletion of insulin-degrading enzyme elicits antipodal, age-dependent effects on glucose and insulin tolerance SO Abdul-Hay, D Kang, M McBride, L Li, J Zhao, MA Leissring PloS one 6 (6), e20818, 2011 | 127 | 2011 |
| Identification of BACE2 as an avid ss-amyloid-degrading protease SO Abdul-Hay, T Sahara, M McBride, D Kang, MA Leissring Molecular neurodegeneration 7, 1-12, 2012 | 78 | 2012 |
| ApoE variant p. V236E is associated with markedly reduced risk of Alzheimer’s disease CW Medway, S Abdul-Hay, T Mims, L Ma, G Bisceglio, F Zou, S Pankratz, ... Molecular neurodegeneration 9, 1-5, 2014 | 66 | 2014 |
| Optimization of peptide hydroxamate inhibitors of insulin-degrading enzyme reveals marked substrate-selectivity SO Abdul-Hay, AL Lane, TR Caulfield, C Claussin, J Bertrand, A Masson, ... Journal of medicinal chemistry 56 (6), 2246-2255, 2013 | 61 | 2013 |
| Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40 CN Suire, SO Abdul-Hay, T Sahara, D Kang, MK Brizuela, P Saftig, ... Alzheimer's research & therapy 12, 1-13, 2020 | 43 | 2020 |
| Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality T Dunlap, SO Abdul-Hay, REP Chandrasena, GK Hagos, V Sinha, ... Nitric Oxide 19 (2), 115-124, 2008 | 41 | 2008 |
| Characterization of insulin degrading enzyme and other amyloid-β degrading proteases in human serum: a role in Alzheimer's disease? Z Liu, H Zhu, GG Fang, K Walsh, M Mwamburi, B Wolozin, SO Abdul-Hay, ... Journal of Alzheimer's Disease 29 (2), 329-340, 2012 | 39 | 2012 |
| NO‐flurbiprofen reduces amyloid‐β, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade SO Abdul‐Hay, J Luo, RT Ashghodom, GRJ Thatcher Journal of neurochemistry 111 (3), 766-776, 2009 | 34 | 2009 |
| Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates IT Schiefer, S Abdul-Hay, H Wang, M Vanni, Z Qin, GRJ Thatcher Journal of medicinal chemistry 54 (7), 2293-2306, 2011 | 29 | 2011 |
| Quinone Induced Activation of Keap1/Nrf2 Signaling by Aspirin Prodrugs Masquerading as Nitric Oxide. TGR Dunlap TL, Piyankarage S, Abdul-Hay S Chemical research in toxicology, 2012 | 28 | 2012 |
| Selective targeting of extracellular insulin-degrading enzyme by quasi-irreversible thiol-modifying inhibitors SO Abdul-Hay, TD Bannister, H Wang, MD Cameron, TR Caulfield, ... ACS chemical biology 10 (12), 2716-2724, 2015 | 26 | 2015 |
| Anti-inflammatory, antiproliferative, and cytoprotective activity of NO chimera nitrates of use in cancer chemoprevention GK Hagos, SO Abdul-Hay, J Sohn, PD Edirisinghe, REP Chandrasena, ... Molecular pharmacology 74 (5), 1381-1391, 2008 | 25 | 2008 |
| NO-SSRIs: nitric oxide chimera drugs incorporating a selective serotonin reuptake inhibitor S Abdul-Hay, IT Schiefer, REP Chandrasena, M Li, R Abdelhamid, ... ACS medicinal chemistry letters 2 (9), 656-661, 2011 | 24 | 2011 |
| Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors SR Chirapu, B Pachaiyappan, HF Nural, X Cheng, H Yuan, DC Lankin, ... Bioorganic & medicinal chemistry letters 19 (1), 264-274, 2009 | 22 | 2009 |
| Selective modulation of amyloid‐β peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Aβ levels SO Abdul‐Hay, P Edirisinghe, GRJ Thatcher Journal of neurochemistry 111 (3), 683-695, 2009 | 21 | 2009 |
| LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer’s disease (LOAD) S Lincoln, M Allen, CL Cox, LP Walker, K Malphrus, Y Qiu, T Nguyen, ... PloS one 8 (6), e64164, 2013 | 19 | 2013 |
| Age and its association with low insulin and high amyloid-β peptides in blood H Li, H Zhu, M Wallack, M Mwamburi, SO Abdul-Hay, MA Leissring, ... Journal of Alzheimer's Disease 49 (1), 129-137, 2016 | 18 | 2016 |
| ML345, a small-molecule inhibitor of the insulin-degrading enzyme (IDE) TD Bannister, H Wang, SO Abdul-Hay, A Masson, F Madoux, J Ferguson, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2014 | 17 | 2014 |
| The blood glucose-lowering effect of racecadotril is not attributable to inhibition of insulin-degrading enzyme S Kurklinsky, SO Abdul-Hay, MP McGuire, EA Howard, J Knight, ... Hormone and metabolic research 46 (01), 73-74, 2014 | 2 | 2014 |
