Albert J. R. Heck

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Shabaz MohammedAssociate Professor of Proteomics, University of OxfordVerified email at bioch.ox.ac.uk
Maarten AltelaarProfessor, Universiteit UtrechtVerified email at uu.nl
Jeroen KrijgsveldGerman Cancer Research Center & Heidelberg UniversityVerified email at dkfz.de
Arjen ScholtenPrincipal Scientist Analytical Development; Janssen Vaccines & PreventionVerified email at its.jnj.com
Teck Yew LowUKM Medical Molecular Biology InstituteVerified email at ppukm.ukm.edu.my
Reinout RaijmakersManaging Director, Bijvoet Center, Utrecht UniversityVerified email at uu.nl
Joost SnijderUtrecht UniversityVerified email at uu.nl
Henk van den ToornBioinformatician at Biomolecular Mass Spectrometry and Proteomics Group, Utrecht UniversityVerified email at uu.nl
Javier MuñozBiocruces BizkaiaVerified email at osakidetza.eus
Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
Richard ScheltemaAssociate Professor at Utrecht UniversityVerified email at uu.nl
Alexander A. MakarovThermo Fisher ScientificVerified email at thermofisher.com
C. MummeryLeiden University Medical Centre and University of TwenteVerified email at lumc.nl
Fabio MarinoDipartimento di Scienze Chimiche, Farmaceutiche, Biologiche ed Ambientali. UNIME. CONISMA.Verified email at unime.it
Fan LiuLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)Verified email at fmp-berlin.de
Vojtech FrancSr. Scientist Analytical Technology at Pharming GroupVerified email at pharming.com
Joost W. GouwScientist at Nutricia ResearchVerified email at interchange.ubc.ca
Philip LösslSenior Editor, Nature CommunicationsVerified email at nature.com
Daniele GuardavaccaroUniversity of VeronaVerified email at univr.it
Christian K. FreseBayerVerified email at bayer.com

Albert J. R. Heck

Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht University

Verified email at uu.nl - Homepage

Mass Spectrometry Proteomics Analytical Chemistry Stem Cells Pharmaceutical Sciences


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The CRAPome: a contaminant repository for affinity purification–mass spectrometry data D Mellacheruvu, Z Wright, AL Couzens, JP Lambert, NA St-Denis, T Li, ... Nature methods 10 (8), 730-736, 2013	1577	2013
Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics PJ Boersema, R Raijmakers, S Lemeer, S Mohammed, AJR Heck Nature protocols 4 (4), 484-494, 2009	1554	2009
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293-297, 2011	1338	2011
Selective isolation at the femtomole level of phosphopeptides from proteolytic digests using 2D-NanoLC-ESI-MS/MS and titanium oxide precolumns MWH Pinkse, PM Uitto, MJ Hilhorst, B Ooms, AJR Heck Analytical chemistry 76 (14), 3935-3943, 2004	1111	2004
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex VSW Li, SS Ng, PJ Boersema, TY Low, WR Karthaus, JP Gerlach, ... Cell 149 (6), 1245-1256, 2012	990	2012
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors BK Koo, M Spit, I Jordens, TY Low, DE Stange, M Van De Wetering, ... Nature 488 (7413), 665-669, 2012	931	2012
Next-generation proteomics: towards an integrative view of proteome dynamics AFM Altelaar, J Munoz, AJR Heck Nature Reviews Genetics 14 (1), 35-48, 2013	844	2013
Native mass spectrometry: a bridge between interactomics and structural biology AJR Heck Nature methods 5 (11), 927-933, 2008	844	2008
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers J Muñoz, DE Stange, AG Schepers, M Van De Wetering, BK Koo, ... The EMBO journal 31 (14), 3079-3091, 2012	794	2012
The minimum information about a proteomics experiment (MIAPE) CF Taylor, NW Paton, KS Lilley, PA Binz, RK Julian Jr, AR Jones, W Zhu, ... Nature biotechnology 25 (8), 887-893, 2007	788	2007
Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis JJ Benschop, S Mohammed, M O'Flaherty, AJR Heck, M Slijper, ... Molecular & Cellular Proteomics 6 (7), 1198-1214, 2007	767	2007
Investigation of intact protein complexes by mass spectrometry AJR Heck, RHH Van Den Heuvel Mass spectrometry reviews 23 (5), 368-389, 2004	730	2004
Complement is activated by IgG hexamers assembled at the cell surface CA Diebolder, FJ Beurskens, RN De Jong, RI Koning, K Strumane, ... Science 343 (6176), 1260-1263, 2014	723	2014
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions B Wiedenheft, E van Duijn, JB Bultema, SP Waghmare, K Zhou, ... Proceedings of the National Academy of Sciences 108 (25), 10092-10097, 2011	691	2011
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529-536, 2011	673	2011
Native mass spectrometry: what is in the name? AC Leney, AJR Heck Journal of the American Society for Mass Spectrometry 28 (1), 5-13, 2016	548	2016
Ion mobility mass spectrometry of proteins and protein assemblies C Uetrecht, RJ Rose, E van Duijn, K Lorenzen, AJR Heck Chemical Society Reviews 39 (5), 1633-1655, 2010	542	2010
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ... Nature 549 (7670), 106-110, 2017	534	2017
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice E de Boer, P Rodriguez, E Bonte, J Krijgsveld, E Katsantoni, A Heck, ... Proceedings of the National Academy of Sciences 100 (13), 7480-7485, 2003	518	2003
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics J Krijgsveld, RF Ketting, T Mahmoudi, J Johansen, M Artal-Sanz, ... Nature biotechnology 21 (8), 927-931, 2003	505	2003

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