| Identification of seven loci affecting mean telomere length and their association with disease V Codd, CP Nelson, E Albrecht, M Mangino, J Deelen, JL Buxton, ... Nature genetics 45 (4), 422-427, 2013 | 849 | 2013 |
| Whole-genome sequence variation, population structure and demographic history of the Dutch population Nature genetics 46 (8), 818-825, 2014 | 652 | 2014 |
| Disease variants alter transcription factor levels and methylation of their binding sites MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ... Nature genetics 49 (1), 131-138, 2017 | 373 | 2017 |
| Epigenetic variation during the adult lifespan: cross‐sectional and longitudinal data on monozygotic twin pairs RP Talens, K Christensen, H Putter, G Willemsen, L Christiansen, ... Aging cell 11 (4), 694-703, 2012 | 336 | 2012 |
| Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited J Deelen, M Beekman, HW Uh, Q Helmer, M Kuningas, L Christiansen, ... Aging cell 10 (4), 686-698, 2011 | 308 | 2011 |
| The Genome of the Netherlands: design, and project goals DI Boomsma, C Wijmenga, EP Slagboom, MA Swertz, LC Karssen, ... European Journal of Human Genetics 22 (2), 221-227, 2014 | 291 | 2014 |
| Genetic and environmental influences interact with age and sex in shaping the human methylome J Van Dongen, MG Nivard, G Willemsen, JJ Hottenga, Q Helmer, ... Nature communications 7 (1), 11115, 2016 | 289 | 2016 |
| Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array RC Slieker, SD Bos, JJ Goeman, JVMG Bovée, RP Talens, ... Epigenetics & chromatin 6 (1), 1-12, 2013 | 242 | 2013 |
| The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection G Willemsen, JM Vink, A Abdellaoui, A Den Braber, JHDA Van Beek, ... Twin Research and Human Genetics 16 (1), 271-281, 2013 | 220 | 2013 |
| The Netherlands Twin Register biobank: a resource for genetic epidemiological studies G Willemsen, EJC De Geus, M Bartels, CEMT Van Beijsterveldt, AI Brooks, ... Twin Research and Human Genetics 13 (3), 231-245, 2010 | 190 | 2010 |
| A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer BT Heijmans, JMA Boer, HED Suchiman, CJ Cornelisse, ... Cancer research 63 (6), 1249-1253, 2003 | 187 | 2003 |
| Small nucleoli are a cellular hallmark of longevity V Tiku, C Jain, Y Raz, S Nakamura, B Heestand, W Liu, M Späth, ... Nature communications 8 (1), 16083, 2017 | 185 | 2017 |
| Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity M Beekman, C Nederstigt, HED Suchiman, D Kremer, R van der Breggen, ... Proceedings of the National Academy of Sciences 107 (42), 18046-18049, 2010 | 170 | 2010 |
| Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome EW Tobi, RC Slieker, AD Stein, HED Suchiman, PE Slagboom, ... International journal of epidemiology 44 (4), 1211-1223, 2015 | 145 | 2015 |
| DNA methylation analysis identifies loci for blood pressure regulation MA Richard, T Huan, S Ligthart, R Gondalia, MA Jhun, JA Brody, MR Irvin, ... The American Journal of Human Genetics 101 (6), 888-902, 2017 | 138 | 2017 |
| Characteristics of de novo structural changes in the human genome WP Kloosterman, LC Francioli, F Hormozdiari, T Marschall, JY Hehir-Kwa, ... Genome research 25 (6), 792-801, 2015 | 137 | 2015 |
| RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage RC de Almeida, YFM Ramos, A Mahfouz, W den Hollander, N Lakenberg, ... Annals of the rheumatic diseases 78 (2), 270-277, 2019 | 121 | 2019 |
| Improving phenotypic prediction by combining genetic and epigenetic associations S Shah, MJ Bonder, RE Marioni, Z Zhu, AF McRae, A Zhernakova, ... The American Journal of Human Genetics 97 (1), 75-85, 2015 | 120 | 2015 |
| Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’ P Deelen, A Menelaou, EM Van Leeuwen, A Kanterakis, F Van Dijk, ... European Journal of Human Genetics 22 (11), 1321-1326, 2014 | 109 | 2014 |
| Evidence from case–control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity M Soerensen, S Dato, Q Tan, M Thinggaard, R Kleindorp, M Beekman, ... Age 35, 487-500, 2013 | 103 | 2013 |
