Adam Heikal
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Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation
A Heikal, Y Nakatani, E Dunn, MR Weimar, CL Day, EN Baker, JS Lott, ...
Molecular microbiology 91 (5), 950-964, 2014
Oxidative phosphorylation as a target space for tuberculosis: success, caution, and future directions
GM Cook, K Hards, E Dunn, A Heikal, Y Nakatani, C Greening, DC Crick, ...
Tuberculosis and the Tubercle Bacillus, 295-316, 2017
Regulation of proline metabolism in mycobacteria and its role in carbon metabolism under hypoxia
M Berney, MR Weimar, A Heikal, GM Cook
Molecular microbiology 84 (4), 664-681, 2012
The mechanism of catalysis by type-II NADH: quinone oxidoreductases
JN Blaza, HR Bridges, D Aragão, EA Dunn, A Heikal, GM Cook, ...
Scientific reports 7 (1), 40165, 2017
Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis
EA Dunn, M Roxburgh, L Larsen, RAJ Smith, AD McLellan, A Heikal, ...
Bioorganic & medicinal chemistry 22 (19), 5320-5328, 2014
Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death
A Heikal, K Hards, CY Cheung, A Menorca, MSM Timmer, BL Stocker, ...
Journal of Antimicrobial Chemotherapy 71 (10), 2840-2847, 2016
Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors
C Schnaars, G Kildahl-Andersen, A Prandina, R Popal, S Radix, ...
ACS Infectious Diseases 4 (9), 1407-1422, 2018
Oxidative phosphorylation as a target space for tuberculosis: success, caution, and future directions. Microbiol Spectr 5
GM Cook, K Hards, E Dunn, A Heikal, Y Nakatani, C Greening, DC Crick, ...
TBTB2–0014-2016, 2017
The stabilisation of purified, reconstituted P-glycoprotein by freeze drying with disaccharides
A Heikal, K Box, A Rothnie, J Storm, R Callaghan, M Allen
Cryobiology 58 (1), 37-44, 2009
ZN148 Is a Modular Synthetic Metallo-β-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo
Ø Samuelsen, OAH Åstrand, C Fröhlich, A Heikal, S Skagseth, ...
Antimicrobial Agents and Chemotherapy 64 (6), 10.1128/aac. 02415-19, 2020
Multiple bactericidal mechanisms of the zinc ionophore PBT2
N Harbison-Price, SA Ferguson, A Heikal, G Taiaroa, K Hards, Y Nakatani, ...
Msphere 5 (2), 10.1128/msphere. 00157-20, 2020
Bacillus cereus biofilm formation on central venous catheters of hospitalised cardiac patients
S Ikram, A Heikal, S Finke, A Hofgaard, Y Rehman, AN Sabri, OA Økstad
Biofouling 35 (2), 204-216, 2019
Metal chelation by a plant lignan, secoisolariciresinol diglucoside
F Fucassi, A Heikal, LI Mikhalovska, G Standen, IU Allan, SV Mikhalovsky, ...
Journal of Inclusion Phenomena and Macrocyclic Chemistry 80, 345-351, 2014
‘Tethering’fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase
A Heikal, Y Nakatani, W Jiao, C Wilson, D Rennison, MR Weimar, ...
Bioorganic & Medicinal Chemistry Letters 28 (13), 2239-2243, 2018
Substituted sulfonamide bioisosteres of 8-hydroxyquinoline as zinc-dependent antibacterial compounds
JE McGowan, AD Harper, EK Davison, JY Jeong, S Mros, ...
Bioorganic & Medicinal Chemistry Letters 30 (11), 127110, 2020
Complete genome sequence of pseudomonas aeruginosa K34-7, a carbapenem-resistant isolate of the high-risk sequence type 233
G Taiaroa, Ø Samuelsen, T Kristensen, OAL Økstad, A Heikal
Microbiology Resource Announcements 7 (4), 10.1128/mra. 00886-18, 2018
Complete Genome Sequence of a Multidrug-Resistant, blaNDM-1-Expressing Klebsiella pneumoniae K66-45 Clinical Isolate from Norway
A Heikal, Ø Samuelsen, T Kristensen, OA Økstad
Genome Announcements 5 (27), 10.1128/genomea. 00601-17, 2017
C-2 derivatized 8-sulfonamidoquinolines as antibacterial compounds
EK Davison, JE McGowan, FF Li, AD Harper, JY Jeong, S Mros, ...
Bioorganic & Medicinal Chemistry 29, 115837, 2021
Microtiter screening reveals oxygen-dependent antimicrobial activity of natural products against mastitis-causing bacteria
SA Ferguson, A Menorca, EM Van Zuylen, CY Cheung, MA McConnell, ...
Frontiers in Microbiology 10, 1995, 2019
Complete Genome Sequence of a New Zealand Isolate of the Bovine Pathogen Streptococcus uberis
G Taiaroa, N Harbison-Price, SA Ferguson, GP Carter, DA Williamson, ...
Genome Announcements 6 (9), e00119-18, 2018
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