| DNA methylation signatures link prenatal famine exposure to growth and metabolism EW Tobi, JJ Goeman, R Monajemi, H Gu, H Putter, Y Zhang, RC Slieker, ... Nature communications 5 (1), 5592, 2014 | 598 | 2014 |
| MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4 MG Huijbers, W Zhang, R Klooster, EH Niks, MB Friese, KR Straasheijm, ... Proceedings of the National Academy of Sciences 110 (51), 20783-20788, 2013 | 282 | 2013 |
| SOX antibodies in small-cell lung cancer and Lambert-Eaton myasthenic syndrome: frequency and relation with survival MJ Titulaer, R Klooster, M Potman, L Sabater, F Graus, IM Hegeman, ... Journal of clinical oncology 27 (26), 4260-4267, 2009 | 234 | 2009 |
| Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome PE Thijssen, Y Ito, G Grillo, J Wang, G Velasco, H Nitta, M Unoki, ... Nature communications 6 (1), 7870, 2015 | 173 | 2015 |
| Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways J Deelen, HW Uh, R Monajemi, D van Heemst, PE Thijssen, S Böhringer, ... Age 35, 235-249, 2013 | 151 | 2013 |
| Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects CMR Weemaes, MJ Van Tol, J Wang, MM van Ostaijen-Ten Dam, ... European Journal of Human Genetics 21 (11), 1219-1225, 2013 | 145 | 2013 |
| Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHD YD Krom, PE Thijssen, JM Young, B den Hamer, J Balog, Z Yao, L Maves, ... PLoS genetics 9 (4), e1003415, 2013 | 116 | 2013 |
| Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers J Deelen, M Beekman, V Codd, S Trompet, L Broer, S Hägg, K Fischer, ... International journal of epidemiology 43 (3), 878-886, 2014 | 109 | 2014 |
| The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80 D Typas, MS Luijsterburg, WW Wiegant, M Diakatou, A Helfricht, ... Nucleic acids research 43 (14), 6919-6933, 2015 | 88 | 2015 |
| Correlation analysis of clinical parameters with epigenetic modifications in the DUX4 promoter in FSHD J Balog, PE Thijssen, JC de Greef, B Shah, BGM van Engelen, ... Epigenetics 7 (6), 579-584, 2012 | 66 | 2012 |
| Increased DUX4 expression during muscle differentiation correlates with decreased SMCHD1 protein levels at D4Z4 J Balog, PE Thijssen, S Shadle, KR Straasheijm, PJ van der Vliet, ... Epigenetics 10 (12), 1133-1142, 2015 | 63 | 2015 |
| Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining A Helfricht, W Wiegant, P Thijssen, A Vertegaal, M Luijsterburg, ... Cell cycle 12 (18), 3070-3082, 2013 | 62 | 2013 |
| Converging disease genes in ICF syndrome: ZBTB24 controls expression of CDCA7 in mammals H Wu, PE Thijssen, E de Klerk, KKD Vonk, J Wang, B den Hamer, ... Human molecular genetics 25 (18), 4041-4051, 2016 | 58 | 2016 |
| Expanding the mutation spectrum in ICF syndrome: Evidence for a gender bias in ICF2 ML Van den Boogaard, PE Thijssen, C Aytekin, F Licciardi, AA Kıykım, ... Clinical genetics 92 (4), 380-387, 2017 | 34 | 2017 |
| Adipocyte telomere length associates negatively with adipocyte size, whereas adipose tissue telomere length associates negatively with the extent of fibrosis in severely obese … F El Bouazzaoui, P Henneman, P Thijssen, A Visser, F Koning, MA Lips, ... International journal of obesity 38 (5), 746-749, 2014 | 33 | 2014 |
| Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes PE Thijssen, EW Tobi, J Balog, SG Schouten, D Kremer, F El Bouazzaoui, ... Epigenetics 8 (5), 512-521, 2013 | 30 | 2013 |
| Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome A Helfricht, PE Thijssen, MB Rother, RG Shah, L Du, S Takada, M Rogier, ... Journal of Experimental Medicine 217 (11), e20191688, 2020 | 29 | 2020 |
| Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent … D Pons, S Trompet, AJM de Craen, PE Thijssen, PHA Quax, MR de Vries, ... Heart 97 (2), 143-150, 2011 | 28 | 2011 |
| DUX4 promotes transcription of FRG2 by directly activating its promoter in facioscapulohumeral muscular dystrophy PE Thijssen, J Balog, Z Yao, TP Pham, R Tawil, SJ Tapscott, ... Skeletal muscle 4, 1-9, 2014 | 25 | 2014 |
| DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nat Commun. 2014; 5: 5592 EW Tobi, JJ Goeman, R Monajemi, H Gu, H Putter, Y Zhang, RC Slieker, ... This study of Dutch Hunger Winter survivors exposed to famine in utero …, 0 | 17 | |
Silvère van der MaarelProfessor of Medical Epigenetics, Head of Department, Human Genetics, Leiden University MedicalGeverifieerd e-mailadres voor lumc.nl
