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Jonathan Wren
Jonathan Wren
Bioinformatics Core Director & Associate Member, Oklahoma Medical Research Foundation
Adresse e-mail validée de omrf.org
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The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
YI Zhu, T Tchkonia, T Pirtskhalava, AC Gower, H Ding, N Giorgadze, ...
Aging cell 14 (4), 644-658, 2015
19922015
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
YI Zhu, T Tchkonia, H Fuhrmann‐Stroissnigg, HM Dai, YY Ling, MB Stout, ...
Aging cell 15 (3), 428-435, 2016
9292016
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
CJ Lessard, H Li, I Adrianto, JA Ice, A Rasmussen, KM Grundahl, JA Kelly, ...
Nature genetics 45 (11), 1284-1292, 2013
5542013
Computer program products, systems and methods for information discovery and relational analyses
H Garner, J Wren
US Patent App. 10/665,981, 2004
3382004
Endothelial dysfunction and angiogenesis impairment in the ageing vasculature
Z Ungvari, S Tarantini, T Kiss, JD Wren, CB Giles, CT Griffin, WL Murfee, ...
Nature Reviews Cardiology 15 (9), 555-565, 2018
3212018
Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients
P Coit, M Jeffries, N Altorok, MG Dozmorov, KA Koelsch, JD Wren, ...
Journal of autoimmunity 43, 78-84, 2013
3162013
Knowledge discovery by automated identification and ranking of implicit relationships
JD Wren, R Bekeredjian, JA Stewart, RV Shohet, HR Garner
Bioinformatics 20 (3), 389-398, 2004
2692004
The role of DNA methylation in epigenetics of aging
A Unnikrishnan, WM Freeman, J Jackson, JD Wren, H Porter, ...
Pharmacology & therapeutics 195, 172-185, 2019
2602019
The write position: A survey of perceived contributions to papers based on byline position and number of authors
JD Wren, KZ Kozak, KR Johnson, SJ Deakyne, LM Schilling, ...
EMBO reports 8 (11), 988-991, 2007
2552007
Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
M Jeffries, M Dozmorov, Y Tang, JT Merrill, JD Wren, AH Sawalha
Epigenetics 6 (5), 593-601, 2011
2462011
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
C Sun, JE Molineros, LL Looger, X Zhou, K Kim, Y Okada, J Ma, Y Qi, ...
Nature genetics 48 (3), 323-330, 2016
2272016
Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis
JR Daum, JD Wren, JJ Daniel, S Sivakumar, JN McAvoy, TA Potapova, ...
Current Biology 19 (17), 1467-1472, 2009
1952009
Repeat polymorphisms within gene regions: phenotypic and evolutionary implications
JD Wren, E Forgacs, JW Fondon, A Pertsemlidis, SY Cheng, T Gallardo, ...
The American Journal of Human Genetics 67 (2), 345-356, 2000
1942000
Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice
Z Tucsek, P Toth, S Tarantini, D Sosnowska, T Gautam, JP Warrington, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2014
1832014
Plant virus biodiversity and ecology
JD Wren, MJ Roossinck, RS Nelson, K Scheets, MW Palmer, U Melcher
PLoS biology 4 (3), e80, 2006
1812006
Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils
P Coit, S Yalavarthi, M Ognenovski, W Zhao, S Hasni, JD Wren, ...
Journal of autoimmunity 58, 59-66, 2015
1652015
Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular …
A Csiszar, T Gautam, D Sosnowska, S Tarantini, E Banki, Z Tucsek, ...
American Journal of Physiology-Heart and Circulatory Physiology 307 (3 …, 2014
1592014
PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity
T Iwayama, C Steele, L Yao, MG Dozmorov, D Karamichos, JD Wren, ...
Genes & development 29 (11), 1106-1119, 2015
1582015
Extending the mutual information measure to rank inferred literature relationships
JD Wren
BMC bioinformatics 5, 1-13, 2004
1482004
Aging exacerbates hypertension‐induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection
P Toth, S Tarantini, Z Springo, Z Tucsek, T Gautam, CB Giles, JD Wren, ...
Aging Cell 14 (3), 400-408, 2015
1422015
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