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Danai Stella Gkotsi
Danai Stella Gkotsi
Children's Brain Tumours Research Centre(CBTRC), Medicine, University of Nottingham, Biodiscovery In
Geverifieerd e-mailadres voor nottingham.ac.uk
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A marine viral halogenase that iodinates diverse substrates
DS Gkotsi, H Ludewig, SV Sharma, JA Connolly, J Dhaliwal, Y Wang, ...
Nature chemistry 11 (12), 1091-1097, 2019
742019
The First One-Pot Synthesis of l-7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l-7-Halotryptophans
DRM Smith, T Willemse, DS Gkotsi, W Schepens, BUW Maes, S Ballet, ...
Organic letters 16 (10), 2622-2625, 2014
652014
Halogenases: powerful tools for biocatalysis (mechanisms applications and scope)
DS Gkotsi, J Dhaliwal, MMW McLachlan, KR Mulholand, RJM Goss
Current Opinion in Chemical Biology 43, 119-126, 2018
642018
Halogenases: a palette of emerging opportunities for synthetic biology–synthetic chemistry and C–H functionalisation
C Crowe, S Molyneux, SV Sharma, Y Zhang, DS Gkotsi, H Connaris, ...
Chemical Society Reviews 50 (17), 9443-9481, 2021
612021
Halogenases: structures and functions
H Ludewig, S Molyneux, S Ferrinho, K Guo, R Lynch, DS Gkotsi, ...
Current Opinion in Structural Biology 65, 51-60, 2020
232020
Promiscuous indolyl vinyl isonitrile synthases in the biogenesis and diversification of hapalindole-type alkaloids
K Ittiamornkul, Q Zhu, DS Gkotsi, DRM Smith, ML Hillwig, N Nightingale, ...
Chemical Science 6 (12), 6836-6840, 2015
182015
Nicotiana benthamiana as a Transient Expression Host to Produce Auxin Analogs
K Davis, DS Gkotsi, DRM Smith, RJM Goss, L Caputi, SE O’Connor
Frontiers in plant science 11, 581675, 2020
152020
Halogenases
RJMG S Grüschow, DRM Smith, DS Gkotsi
Science of Synthesis: Biocatalysis in Organic Synthesis 3, 313 - 360, 2015
7*2015
A marine viral halogenase that iodinates diverse substrates. Nat Chem 11: 1091–1097
DS Gkotsi, H Ludewig, SV Sharma, JA Connolly, J Dhaliwal, Y Wang, ...
62019
Biocatalysis in Organic Synthesis. Science of Synthesis, Vol. 1-3. Edited by Kurt Faber, Wolf-Dieter Fessner and Nicholas J. Turner.
R Kourist
Angewandte Chemie International Edition 54 (43), 2015
62015
PTCHD1 binds cholesterol but not sonic hedgehog, suggesting a distinct cellular function
MK Hiltunen, AJ Timmis, M Thomsen, DS Gkotsi, H Iwaï, OM Ribeiro, ...
International Journal of Molecular Sciences 24 (3), 2682, 2023
32023
Identifying an iodinase
C Schnepel, NJ Turner
Nature Chemistry 11 (12), 1076-1078, 2019
32019
Discovery and utilisation of wildly different halogenases, powerful new tools for medicinal chemistry
RJM Goss, DS Gkotsi
UK patent GB1803491 8, 2018
22018
Signaling switching from Hedgehog-GLI to MAPK signaling potentially serves as a compensatory mechanism in melanoma cell lines resistant to GANT-61
N Piteša, M Kurtović, N Bartoniček, DS Gkotsi, J Čonkaš, T Petrić, ...
Biomedicines 11 (5), 1353, 2023
2023
First Insights into the Characterization of GANT61-Resistant Melanoma Cell Lines
N Piteša, M Kurtović, N Bartoniček, DS Gkotsi, J Čonkaš, T Petrić, ...
Hedgehog signaling: From molecular structure to dveelopmental biology and …, 2023
2023
The Hedgehog receptors PTCH1 and PTCH2 exist as active homomeric and heteromeric complexes
AJ Timmis, F Cross, DS Gkotsi, H Ollerton, CA Johnson, ...
bioRxiv, 2023.08. 08.549832, 2023
2023
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability
B Caballero-Ruiz, DS Gkotsi, H Ollerton, CC Morales-Alcala, R Bordone, ...
Cancers 15 (2), 369, 2022
2022
Iodine goes viral
C Deane
Nature Chemical Biology 15 (12), 1131-1131, 2019
2019
In vivo proton MR spectroscopy of gliomatosis cerebri: Diagnosis and exploration of tumor metabolism
ED Gotsis, DS Gkotsi, G Pissakas, I Seimenis
Physica Medica 32, 248, 2016
2016
SIMPLE AND SCALABLE ACCES TO L-7-HALOTRYPTOPHANS AND OTHER L-HALOTRYPTOPHANS THROUGH AN IMPROVED ONE-POT BIOTRANSFORMATION
T Willemse, DRM Smith, D Gkotsi, W Schepens, BUW Maes, S Ballet, ...
Journal of Peptide Science 20 (s1), S143-S144, 2014
2014
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Artikelen 1–20