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William A Paxton
William A Paxton
Professor of Infection and Global Health
Geverifieerd e-mailadres voor liverpool.ac.uk
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HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
T Dragic, V Litwin, GP Allaway, SR Martin, Y Huang, KA Nagashima, ...
Nature 381 (6584), 667-673, 1996
43431996
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
R Liu, WA Paxton, S Choe, D Ceradini, SR Martin, R Horuk, ...
Cell 86 (3), 367-377, 1996
40091996
The role of a mutant CCR5 allele in HIV–1 transmission and disease progression
Y Huang, WA Paxton, SM Wolinsky, AU Neumann, L Zhang, T He, S Kang, ...
Nature Medicine 2 (11), 1240-1243, 1996
17761996
Genetic mechanisms of critical illness in COVID-19
E Pairo-Castineira
Nature 591 (7848), 92-98, 2021
12962021
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
SR Knight
BMJ, 2020
10052020
SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses
W Dejnirattisai, J Huo, D Zhou, J Zahradník, P Supasa, C Liu, ...
Cell 185 (3), 467-484. e15, 2022
8932022
CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro
L Wu, WA Paxton, N Kassam, N Ruffing, JB Rottman, N Sullivan, H Choe, ...
Journal of Experimental Medicine 185 (9), 1681-1692, 1997
8841997
Relative resistance to HIV–1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high–risk sexual exposures
WA Paxton, SR Martin, D Tse, TR O'Brien, J Skurnick, NL VanDevanter, ...
Nature Medicine 2 (4), 412-417, 1996
8671996
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7122021
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study
OV Swann
BMJ, 2020
7032020
Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis.
W Paxton, RI Connor, NR Landau
Journal of Virology 67 (12), 7229-7237, 1993
5781993
Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M-and T-tropic …
A Granelli-Piperno, E Delgado, V Finkel, W Paxton, RM Steinman
Journal of Virology 72 (4), 2733-2737, 1998
4031998
N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization
G Pollakis, S Kang, A Kliphuis, MIM Chalaby, J Goudsmit, WA Paxton
Journal of Biological Chemistry 276 (16), 13433-13441, 2001
3272001
Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors
A Granelli-Piperno, B Moser, M Pope, D Chen, Y Wei, F Isdell, ...
Journal of Experimental Medicine 184 (6), 2433-2438, 1996
3011996
Preferential infection and depletion of Mycobacterium tuberculosis–specific CD4 T cells after HIV-1 infection
C Geldmacher, N Ngwenyama, A Schuetz, C Petrovas, K Reither, ...
Journal of Experimental Medicine 207 (13), 2869-2881, 2010
2952010
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre …
CD Russell, CJ Fairfield, TM Drake, L Turtle, RA Seaton, DG Wootton, ...
The Lancet Microbe 2 (8), e354-e365, 2021
2772021
Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study
TM Drake
American Journal of Respiratory and Critical Care Medicine 202 (12), 1656-1665, 2020
2202020
Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes
MA Naarding, IS Ludwig, F Groot, B Berkhout, TBH Geijtenbeek, ...
Journal of Clinical Investigation 115 (11), 3256-3264, 2005
2152005
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
RK Gupta, EM Harrison, A Ho, AB Docherty, SR Knight, M van Smeden, ...
The Lancet Respiratory Medicine 9 (4), 349-359, 2021
2072021
Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of β-chemokines
WA Paxton, R Liu, S Kang, L Wu, TR Gingeras, NR Landau, CR Mackay, ...
Virology 244 (1), 66-73, 1998
2041998
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Artikelen 1–20