Minke A.E. Rab
Minke A.E. Rab
Hematologist, Assistant professor
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Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients
MAE Rab, BA van Oirschot, J Bos, TH Merkx, ACW van Wesel, ...
American journal of hematology 94 (5), 575-584, 2019
AG-348 (mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and adenosine triphosphate levels over a broad …
MAE Rab, BA Van Oirschot, PA Kosinski, J Hixon, K Johnson, ...
Haematologica 106 (1), 238, 2021
Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis
R Huisjes, A Makhro, E Llaudet-Planas, L Hertz, P Petkova-Kirova, ...
haematologica 105 (2), 338, 2020
Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy
MAE Rab, J Bos, BA van Oirschot, S van Straaten, PA Kosinski, ...
Blood, The Journal of the American Society of Hematology 137 (21), 2997-3001, 2021
Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in sickle cell disease: a phase 2, open-label study
MJ van Dijk, MAE Rab, BA van Oirschot, J Bos, C Derichs, AW Rijneveld, ...
American journal of hematology 97 (7), E226-E229, 2022
Oxygen gradient ektacytometry‐derived biomarkers are associated with vaso‐occlusive crises and correlate with treatment response in sickle cell disease
MAE Rab, CK Kanne, J Bos, BA van Oirschot, C Boisson, ME Houwing, ...
American journal of hematology 96 (1), E29, 2021
PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis
PL Moura, BR Hawley, JGG Dobbe, GJ Streekstra, MAE Rab, P Bianchi, ...
Haematologica 105 (6), e268, 2020
Blood rheology biomarkers in sickle cell disease
M Lu, MAE Rab, SS Shevkoplyas, VA Sheehan
Experimental Biology and Medicine 245 (2), 155-165, 2020
Methodological aspects of the oxygenscan in sickle cell disease: a need for standardization
MAE Rab, CK Kanne, J Bos, C Boisson, BA van Oirschot, E Nader, ...
American Journal of Hematology 95 (1), E5, 2020
Mechanical Stress Induces Ca2+-Dependent Signal Transduction in Erythroblasts and Modulates Erythropoiesis
F Aglialoro, A Abay, N Yagci, MAE Rab, L Kaestner, R van Wijk, ...
International journal of molecular sciences 22 (2), 955, 2021
Characterization of sickling during controlled automated deoxygenation with oxygen gradient ektacytometry
MAE Rab, BA van Oirschot, J Bos, CK Kanne, VA Sheehan, EJ van Beers, ...
JoVE (Journal of Visualized Experiments), e60213, 2019
Persistent changes in circulating white blood cell populations after splenectomy
MAE Rab, A Meerveld-Eggink, H van Velzen-Blad, D van Loon, ...
International Journal of Hematology 107, 157-165, 2018
Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia–A Case Study
AS Cloos, LGM Daenen, M Maja, A Stommen, J Vanderroost, ...
Frontiers in Physiology 12, 638027, 2021
Methodological aspects of oxygen gradient ektacytometry in sickle cell disease: Effects of sample storage on outcome parameters in distinct patient subgroups
C Boisson, MAE Rab, E Nader, C Renoux, BA van Oirschot, P Joly, R Fort, ...
Clinical Hemorheology and Microcirculation 77 (4), 391-394, 2021
Effects of genotypes and treatment on oxygenscan parameters in sickle cell disease
C Boisson, MAE Rab, E Nader, C Renoux, C Kanne, J Bos, ...
Cells 10 (4), 811, 2021
A functional spleen contributes to afucosylated IgG in humans
I Wojcik, DE Schmidt, LA de Neef, MAE Rab, B Meek, O de Weerdt, ...
Scientific reports 11 (1), 24045, 2021
Ektacytometry analysis of post-splenectomy red blood cell properties identifies cell membrane stability test as a novel biomarker of membrane health in hereditary spherocytosis
MC Berrevoets, J Bos, R Huisjes, TH Merkx, BA Van Oirschot, ...
Frontiers in Physiology 12, 641384, 2021
Effect of cell age and membrane rigidity on red blood cell shape in capillary flow
M Nouaman, A Darras, T John, G Simionato, MAE Rab, R van Wijk, ...
Cells 12 (11), 1529, 2023
Characterization of genetic variants in the EGLN1/PHD2 gene identified in a European collection of patients with erythrocytosis
M Delamare, A Le Roy, M Pacault, L Schmitt, C Garrec, N Maaziz, ...
Haematologica, 2023
Comprehensive in silico and functional studies for classification of EPAS1/HIF2A genetic variants identified in patients with erythrocytosis
V Karaghiannis, D Maric, C Garrec, N Maaziz, A Buffet, L Schmitt, ...
Haematologica, 2023
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