| Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice AJ Pruijssers, AS George, A Schäfer, SR Leist, LE Gralinksi, KH Dinnon, ... Cell reports 32 (3), 2020 | 482 | 2020 |
| Sialyltransferase regulates nervous system function in Drosophila E Repnikova, K Koles, M Nakamura, J Pitts, H Li, A Ambavane, MJ Zoran, ... Journal of Neuroscience 30 (18), 6466-6476, 2010 | 79 | 2010 |
| Inhibition of flaviviruses by targeting a conserved pocket on the viral envelope protein M de Wispelaere, W Lian, S Potisopon, PC Li, J Jang, SB Ficarro, ... Cell Chemical Biology 25 (8), 1006-1016. e8, 2018 | 75 | 2018 |
| The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion AL Richards, PJ Sollars, JD Pitts, AM Stults, EE Heldwein, GE Pickard, ... PLoS pathogens 13 (12), e1006741, 2017 | 69 | 2017 |
| GNF-2 inhibits dengue virus by targeting Abl kinases and the viral E protein MJ Clark, C Miduturu, AG Schmidt, X Zhu, JD Pitts, J Wang, S Potisopon, ... Cell chemical biology 23 (4), 443-452, 2016 | 67 | 2016 |
| Remdesivir and GS-441524 retain antiviral activity against Delta, Omicron, and other emergent SARS-CoV-2 variants J Pitts, J Li, JK Perry, V Du Pont, N Riola, L Rodriguez, X Lu, C Kurhade, ... Antimicrobial agents and chemotherapy 66 (6), e00222-22, 2022 | 54 | 2022 |
| Crystal structure of the herpesvirus inner tegument protein UL37 supports its essential role in control of viral trafficking JD Pitts, J Klabis, AL Richards, GA Smith, EE Heldwein Journal of virology 88 (10), 5462-5473, 2014 | 50 | 2014 |
| Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial … RL Mackman, HC Hui, M Perron, E Murakami, C Palmiotti, G Lee, K Stray, ... Journal of Medicinal Chemistry 64 (8), 5001-5017, 2021 | 44 | 2021 |
| Antiviral activity of N-(4-hydroxyphenyl) retinamide (4-HPR) against Zika virus JD Pitts, PC Li, M de Wispelaere, PL Yang Antiviral research 147, 124-130, 2017 | 41 | 2017 |
| Key metabolic enzymes involved in remdesivir activation in human lung cells R Li, A Liclican, Y Xu, J Pitts, C Niu, J Zhang, C Kim, X Zhao, D Soohoo, ... Antimicrobial agents and chemotherapy 65 (9), 10.1128/aac. 00602-21, 2021 | 40 | 2021 |
| Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection MS Vermillion, E Murakami, B Ma, J Pitts, A Tomkinson, D Rautiola, ... Science Translational Medicine 14 (633), eabl8282, 2021 | 35 | 2021 |
| Small Molecules Targeting the Flavivirus E Protein with Broad-Spectrum Activity and Antiviral Efficacy in Vivo PC Li, J Jang, CY Hsia, PV Groomes, W Lian, M de Wispelaere, JD Pitts, ... ACS infectious diseases 5 (3), 460-472, 2019 | 32 | 2019 |
| Identification of small molecule inhibitors targeting the Zika virus envelope protein J Pitts, CY Hsia, W Lian, J Wang, MP Pfeil, N Kwiatkowski, Z Li, J Jang, ... Antiviral research 164, 147-153, 2019 | 14 | 2019 |
| Anellovirus structure reveals a mechanism for immune evasion S Liou, N Cohen, Y Zhang, NM Acharekar, H Rodgers, S Islam, L Zeheb, ... BioRxiv, 2022.07. 01.498313, 2022 | 11 | 2022 |
| Discovery of GS-5245 (obeldesivir), an oral prodrug of nucleoside GS-441524 that exhibits antiviral efficacy in SARS-CoV-2-infected African green monkeys RL Mackman, RV Kalla, D Babusis, J Pitts, KT Barrett, K Chun, V Du Pont, ... Journal of Medicinal Chemistry 66 (17), 11701-11717, 2023 | 10 | 2023 |
| Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection J Pitts, D Babusis, MS Vermillion, R Subramanian, K Barrett, D Lye, B Ma, ... Antiviral research 203, 105329, 2022 | 3 | 2022 |
| Anellosomes for delivering protein replacement therapeutic modalities EG Weinstein, A Kahvejian, S Delagrave, NL Yozwiak, KJ Lebo, FM Diaz, ... US Patent App. 17/413,297, 2022 | 3 | 2022 |
| Anellosomes and methods of use EG Weinstein, A Kahvejian, S Delagrave, NL Yozwiak, KJ Lebo, FM Diaz, ... US Patent App. 17/413,392, 2022 | 3 | 2022 |
| Anellovirus compositions and methods of use EG Weinstein, A Kahvejian, S Delagrave, NL Yozwiak, KJ Lebo, FM Diaz, ... US Patent 11,166,996, 2021 | 1 | 2021 |
| Effects of Sialyltransferase Mutation on Drosophila melanogaster Viability, Fertility, and Longevity J Pitts | 1 | 2006 |
