Oscar M Rueda
Oscar M Rueda
MRC Investigator, Programme Leader Track, MRC-BSU. University of Cambridge
Adresse e-mail validée de mrc-bsu.cam.ac.uk - Page d'accueil
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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ...
Nature 486 (7403), 346-352, 2012
44042012
Analysis of circulating tumor DNA to monitor metastatic breast cancer
SJ Dawson, DWY Tsui, M Murtaza, H Biggs, OM Rueda, SF Chin, ...
New England Journal of Medicine 368 (13), 1199-1209, 2013
19192013
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ...
Nature 486 (7403), 395-399, 2012
18422012
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes
B Pereira, SF Chin, OM Rueda, HKM Vollan, E Provenzano, HA Bardwell, ...
Nature communications 7 (1), 1-16, 2016
9372016
Progesterone receptor modulates ERα action in breast cancer
H Mohammed, IA Russell, R Stark, OM Rueda, TE Hickey, GA Tarulli, ...
Nature 523 (7560), 313-317, 2015
5182015
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254-268, 2017
3932017
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer
M Murtaza, SJ Dawson, K Pogrebniak, OM Rueda, E Provenzano, J Grant, ...
Nature communications 6 (1), 1-6, 2015
3782015
Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling
Y Yuan, H Failmezger, OM Rueda, HR Ali, S Gräf, SF Chin, RF Schwarz, ...
Science translational medicine 4 (157), 157ra143-157ra143, 2012
3582012
A new genome‐driven integrated classification of breast cancer and its implications
SJ Dawson, OM Rueda, S Aparicio, C Caldas
The EMBO journal 32 (5), 617-628, 2013
3042013
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds
A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ...
Cell 167 (1), 260-274. e22, 2016
3002016
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor
H Mohammed, C D’Santos, AA Serandour, HR Ali, GD Brown, A Atkins, ...
Cell reports 3 (2), 342-349, 2013
2982013
Copynumber: Efficient algorithms for single-and multi-track copy number segmentation
G Nilsen, K Liestøl, P Van Loo, HKM Vollan, MB Eide, OM Rueda, ...
BMC genomics 13 (1), 1-16, 2012
2082012
TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance
L Silwal-Pandit, HKM Vollan, SF Chin, OM Rueda, S McKinney, T Osako, ...
Clinical Cancer Research 20 (13), 3569-3580, 2014
2012014
Genome-driven integrated classification of breast cancer validated in over 7,500 samples
HR Ali, OM Rueda, SF Chin, C Curtis, MJ Dunning, SAJR Aparicio, ...
Genome biology 15 (8), 1-14, 2014
1782014
RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer
C Cruz, M Castroviejo-Bermejo, S Gutiérrez-Enríquez, A Llop-Guevara, ...
Annals of Oncology 29 (5), 1203-1210, 2018
1492018
Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer
M Michaut, SF Chin, I Majewski, TM Severson, T Bismeijer, L De Koning, ...
Scientific reports 6 (1), 1-13, 2016
1412016
JARID1B is a luminal lineage-driving oncogene in breast cancer
S Yamamoto, Z Wu, HG Russnes, S Takagi, G Peluffo, C Vaske, X Zhao, ...
Cancer cell 25 (6), 762-777, 2014
1372014
Master regulators of FGFR2 signalling and breast cancer risk
MNC Fletcher, MAA Castro, X Wang, I De Santiago, M O’Reilly, SF Chin, ...
Nature communications 4 (1), 1-12, 2013
1362013
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
AA Margolin, E Bilal, E Huang, TC Norman, L Ottestad, BH Mecham, ...
Science translational medicine 5 (181), 181re1-181re1, 2013
1182013
BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
WT Khaled, SC Lee, J Stingl, X Chen, HR Ali, OM Rueda, F Hadi, J Wang, ...
Nature communications 6 (1), 1-10, 2015
1162015
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