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Sieto Bosgra
Sieto Bosgra
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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach
AK Krug, R Kolde, JA Gaspar, E Rempel, NV Balmer, K Meganathan, ...
Archives of toxicology 87, 123-143, 2013
2492013
Toxicokinetic triage for environmental chemicals
JF Wambaugh, BA Wetmore, R Pearce, C Strope, R Goldsmith, JP Sluka, ...
Toxicological Sciences 147 (1), 55-67, 2015
1702015
Evaluation of an alternative in vitro test battery for detecting reproductive toxicants
AH Piersma, S Bosgra, MBM Van Duursen, SAB Hermsen, LRA Jonker, ...
Reproductive Toxicology 38, 53-64, 2013
1052013
An improved model to predict physiologically based model parameters and their inter-individual variability from anthropometry
S Bosgra, J van Eijkeren, P Bos, M Zeilmaker, W Slob
Critical reviews in toxicology 42 (9), 751-767, 2012
892012
An integrated probabilistic framework for cumulative risk assessment of common mechanism chemicals in food: an example with organophosphorus pesticides
S Bosgra, H van der Voet, PE Boon, W Slob
Regulatory Toxicology and Pharmacology 54 (2), 124-133, 2009
862009
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, ...
Archives of toxicology 88, 1109-1126, 2014
792014
Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling
J Louisse, S Bosgra, BJ Blaauboer, IMCM Rietjens, M Verwei
Archives of toxicology 89, 1135-1148, 2015
752015
Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein …
S Bosgra, E van de Steeg, ML Vlaming, KC Verhoeckx, MT Huisman, ...
European Journal of Pharmaceutical Sciences 65, 156-166, 2014
732014
Availability of polychlorinated biphenyls (PCBs) and lindane for uptake by intestinal Caco-2 cells.
AG Oomen, J Tolls, M Kruidenier, SS Bosgra, AJ Sips, JP Groten
Environmental Health Perspectives 109 (7), 731-737, 2001
562001
An expert consortium review of the EC-commissioned report" Alternative (Non-Animal) Methods for Cosmetics Testing: Current Status and Future Prospects-2010".
T Hartung, BJ Blaauboer, S Bosgra, E Carney, J Coenen, RB Conolly, ...
ALTEX 28 (3), 183, 2011
542011
A model for probabilistic health impact assessment of exposure to food chemicals
H van der Voet, GWAM van der Heijden, PMJ Bos, S Bosgra, PE Boon, ...
Food and Chemical Toxicology 47 (12), 2926-2940, 2009
492009
Probabilistic cumulative risk assessment of anti-androgenic pesticides in food
AK Müller, S Bosgra, PE Boon, H van der Voet, E Nielsen, O Ladefoged
Food and Chemical Toxicology 47 (12), 2951-2962, 2009
472009
Probabilistic risk characterization: an example with di (2-ethylhexyl) phthalate
S Bosgra, PMJ Bos, TG Vermeire, RJ Luit, W Slob
Regulatory Toxicology and Pharmacology 43 (1), 104-113, 2005
472005
Evaluation of an alternative in vitro test battery for detecting reproductive toxicants in a grouping context
ED Kroese, S Bosgra, HE Buist, G Lewin, SC van der Linden, H Man, ...
Reproductive Toxicology 55, 11-19, 2015
442015
Suppression of mutant protein expression in SCA3 and SCA1 mice using a CAG repeat-targeting antisense oligonucleotide
E Kourkouta, R Weij, A González-Barriga, M Mulder, R Verheul, S Bosgra, ...
Molecular Therapy-Nucleic Acids 17, 601-614, 2019
422019
Probabilistic modelling of exposure doses and implications for health risk characterization: Glycoalkaloids from potatoes
J Ruprich, I Rehurkova, PE Boon, K Svensson, S Moussavian, ...
Food and chemical toxicology 47 (12), 2899-2905, 2009
412009
Human glycemic response curves after intake of carbohydrate foods are accurately predicted by combining in vitro gastrointestinal digestion with in silico kinetic modeling
S Bellmann, M Minekus, P Sanders, S Bosgra, R Havenaar
Clinical Nutrition Experimental 17, 8-22, 2018
352018
To apply microdosing or not? Recommendations to single out compounds with non-linear pharmacokinetics
S Bosgra, MLH Vlaming, WHJ Vaes
Clinical pharmacokinetics 55, 1-15, 2016
322016
Dose addition and the isobole method as approaches for predicting the cumulative effect of non-interacting chemicals: A critical evaluation
S Bosgra, JCH van Eijkeren, W Slob
Critical Reviews in Toxicology 39 (5), 418-426, 2009
282009
The Pharmacokinetics of 2′-O-Methyl Phosphorothioate Antisense Oligonucleotides: Experiences from Developing Exon Skipping Therapies for Duchenne …
S Bosgra, J Sipkens, S de Kimpe, C den Besten, N Datson, ...
nucleic acid therapeutics 29 (6), 305-322, 2019
262019
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