The expanding universe of p53 targets D Menendez, A Inga, MA Resnick Nature reviews Cancer 9 (10), 724-737, 2009 | 642 | 2009 |
A highly specific SpCas9 variant is identified by in vivo screening in yeast A Casini, M Olivieri, G Petris, C Montagna, G Reginato, G Maule, ... Nature biotechnology 36 (3), 265-271, 2018 | 325 | 2018 |
Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence A Inga, F Storici, TA Darden, MA Resnick Molecular and cellular biology 22 (24), 8612-8625, 2002 | 217 | 2002 |
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis B Leroy, JL Fournier, C Ishioka, P Monti, A Inga, G Fronza, T Soussi Nucleic acids research 41 (D1), D962-D969, 2013 | 180 | 2013 |
Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity MA Resnick, A Inga Proceedings of the National Academy of Sciences 100 (17), 9934-9939, 2003 | 175 | 2003 |
p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements P Campomenosi, P Monti, A Aprile, A Abbondandolo, T Frebourg, B Gold, ... Oncogene 20 (27), 3573-3579, 2001 | 162 | 2001 |
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53 JJ Jordan, D Menendez, A Inga, M Nourredine, D Bell, MA Resnick PLoS genetics 4 (6), e1000104, 2008 | 125 | 2008 |
The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial–Mesenchymal Transition in Breast CancerEMT Can Be Modulated by Fine Tuning MALAT1 and HuR E Latorre, S Carelli, I Raimondi, V D'Agostino, I Castiglioni, C Zucal, ... Cancer research 76 (9), 2626-2636, 2016 | 109 | 2016 |
Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway T Uroda, E Anastasakou, A Rossi, JM Teulon, JL Pellequer, P Annibale, ... Molecular cell 75 (5), 982-995. e9, 2019 | 108 | 2019 |
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts SM Reamon-Buettner, Y Ciribilli, A Inga, J Borlak Human molecular genetics 17 (10), 1397-1405, 2008 | 105 | 2008 |
The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes D Menendez, A Inga, MA Resnick Molecular and cellular biology 26 (6), 2297-2308, 2006 | 94 | 2006 |
More targets, more pathways and more clues for mutant p53 S Garritano, A Inga, F Gemignani, S Landi Oncogenesis 2 (7), e54-e54, 2013 | 93 | 2013 |
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity Z Andrysik, MD Galbraith, AL Guarnieri, S Zaccara, KD Sullivan, A Pandey, ... Genome research 27 (10), 1645-1657, 2017 | 92 | 2017 |
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation DJ Tomso, A Inga, D Menendez, GS Pittman, MR Campbell, F Storici, ... Proceedings of the National Academy of Sciences 102 (18), 6431-6436, 2005 | 89 | 2005 |
A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network D Menendez, O Krysiak, A Inga, B Krysiak, MA Resnick, G Schönfelder Proceedings of the National Academy of Sciences 103 (5), 1406-1411, 2006 | 87 | 2006 |
Tumour p53 mutations exhibit promoter selective dominance over wild type p53 P Monti, P Campomenosi, Y Ciribilli, R Iannone, A Inga, A Abbondandolo, ... Oncogene 21 (11), 1641-1648, 2002 | 77 | 2002 |
Functional evolution of the p53 regulatory network through its target response elements AG Jegga, A Inga, D Menendez, BJ Aronow, MA Resnick Proceedings of the National Academy of Sciences 105 (3), 944-949, 2008 | 76 | 2008 |
Dominant-Negative Features of Mutant TP53 in Germline Carriers Have Limited Impact on Cancer Outcomesp53 Mutant Function and LFS Phenotype P Monti, C Perfumo, A Bisio, Y Ciribilli, P Menichini, D Russo, ... Molecular Cancer Research 9 (3), 271-279, 2011 | 74 | 2011 |
A functional genetic study identifies HAND1 mutations in septation defects of the human heart SM Reamon-Buettner, Y Ciribilli, I Traverso, B Kuhls, A Inga, J Borlak Human molecular genetics 18 (19), 3567-3578, 2009 | 72 | 2009 |
Identification of new p53 target microRNAs by bioinformatics and functional analysis A Bisio, V De Sanctis, V Del Vescovo, MA Denti, AG Jegga, A Inga, ... BMC cancer 13 (1), 1-13, 2013 | 68 | 2013 |