Alberto Inga
Alberto Inga
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The expanding universe of p53 targets
D Menendez, A Inga, MA Resnick
Nature reviews Cancer 9 (10), 724-737, 2009
A highly specific SpCas9 variant is identified by in vivo screening in yeast
A Casini, M Olivieri, G Petris, C Montagna, G Reginato, G Maule, ...
Nature biotechnology 36 (3), 265-271, 2018
Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence
A Inga, F Storici, TA Darden, MA Resnick
Molecular and cellular biology 22 (24), 8612-8625, 2002
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
B Leroy, JL Fournier, C Ishioka, P Monti, A Inga, G Fronza, T Soussi
Nucleic acids research 41 (D1), D962-D969, 2013
Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity
MA Resnick, A Inga
Proceedings of the National Academy of Sciences 100 (17), 9934-9939, 2003
p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements
P Campomenosi, P Monti, A Aprile, A Abbondandolo, T Frebourg, B Gold, ...
Oncogene 20 (27), 3573-3579, 2001
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53
JJ Jordan, D Menendez, A Inga, M Nourredine, D Bell, MA Resnick
PLoS genetics 4 (6), e1000104, 2008
The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial–Mesenchymal Transition in Breast CancerEMT Can Be Modulated by Fine Tuning MALAT1 and HuR
E Latorre, S Carelli, I Raimondi, V D'Agostino, I Castiglioni, C Zucal, ...
Cancer research 76 (9), 2626-2636, 2016
Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway
T Uroda, E Anastasakou, A Rossi, JM Teulon, JL Pellequer, P Annibale, ...
Molecular cell 75 (5), 982-995. e9, 2019
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts
SM Reamon-Buettner, Y Ciribilli, A Inga, J Borlak
Human molecular genetics 17 (10), 1397-1405, 2008
The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes
D Menendez, A Inga, MA Resnick
Molecular and cellular biology 26 (6), 2297-2308, 2006
More targets, more pathways and more clues for mutant p53
S Garritano, A Inga, F Gemignani, S Landi
Oncogenesis 2 (7), e54-e54, 2013
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity
Z Andrysik, MD Galbraith, AL Guarnieri, S Zaccara, KD Sullivan, A Pandey, ...
Genome research 27 (10), 1645-1657, 2017
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation
DJ Tomso, A Inga, D Menendez, GS Pittman, MR Campbell, F Storici, ...
Proceedings of the National Academy of Sciences 102 (18), 6431-6436, 2005
A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network
D Menendez, O Krysiak, A Inga, B Krysiak, MA Resnick, G Schönfelder
Proceedings of the National Academy of Sciences 103 (5), 1406-1411, 2006
Tumour p53 mutations exhibit promoter selective dominance over wild type p53
P Monti, P Campomenosi, Y Ciribilli, R Iannone, A Inga, A Abbondandolo, ...
Oncogene 21 (11), 1641-1648, 2002
Functional evolution of the p53 regulatory network through its target response elements
AG Jegga, A Inga, D Menendez, BJ Aronow, MA Resnick
Proceedings of the National Academy of Sciences 105 (3), 944-949, 2008
Dominant-Negative Features of Mutant TP53 in Germline Carriers Have Limited Impact on Cancer Outcomesp53 Mutant Function and LFS Phenotype
P Monti, C Perfumo, A Bisio, Y Ciribilli, P Menichini, D Russo, ...
Molecular Cancer Research 9 (3), 271-279, 2011
A functional genetic study identifies HAND1 mutations in septation defects of the human heart
SM Reamon-Buettner, Y Ciribilli, I Traverso, B Kuhls, A Inga, J Borlak
Human molecular genetics 18 (19), 3567-3578, 2009
Identification of new p53 target microRNAs by bioinformatics and functional analysis
A Bisio, V De Sanctis, V Del Vescovo, MA Denti, AG Jegga, A Inga, ...
BMC cancer 13 (1), 1-13, 2013
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