Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling G Schreibelt, G Kooij, A Reijerkerk, R Van Doorn, SI Gringhuis, ... The FASEB Journal 21 (13), 3666-3676, 2007 | 394 | 2007 |
MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. MA Lopez-Ramirez, D Wu, G Pryce, JE Simpson, A Reijerkerk, ... FASEB journal 28 (6), 2551-2565, 2014 | 268 | 2014 |
Sphingosine 1‐phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions R Van Doorn, J Van Horssen, D Verzijl, M Witte, E Ronken, B Van Het Hof, ... Glia 58 (12), 1465-1476, 2010 | 230 | 2010 |
Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation PJ Gaillard, CCM Appeldoorn, J Rip, R Dorland, SMA van der Pol, G Kooij, ... Journal of controlled release 164 (3), 364-369, 2012 | 217 | 2012 |
Retinoic acid induces blood–brain barrier development MR Mizee, D Wooldrik, KAM Lakeman, B van het Hof, JAR Drexhage, ... Journal of neuroscience 33 (4), 1660-1671, 2013 | 212 | 2013 |
Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity G Schreibelt, RJP Musters, A Reijerkerk, LR de Groot, S van der Pol, ... The Journal of Immunology 177 (4), 2630-2637, 2006 | 208 | 2006 |
Ultrasound and microbubble-induced intra-and intercellular bioeffects in primary endothelial cells LJM Juffermans, A van Dijk, CAM Jongenelen, B Drukarch, A Reijerkerk, ... Ultrasound in medicine & biology 35 (11), 1917-1927, 2009 | 179 | 2009 |
Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood–brain barrier in rats J Rip, L Chen, R Hartman, A van den Heuvel, A Reijerkerk, J van Kregten, ... Journal of drug targeting 22 (5), 460-467, 2014 | 176 | 2014 |
Diapedesis of monocytes is associated with MMP‐mediated occludin disappearance in brain endothelial cells A Reijerkerk, G Kooij, SM A. van der Pol, S Khazen, CD Dijkstra, ... The FASEB journal 20 (14), 2550-2552, 2006 | 167 | 2006 |
Tissue-type plasminogen activator is a multiligand cross-β structure receptor O Kranenburg, B Bouma, LMJ Kroon-Batenburg, A Reijerkerk, YP Wu, ... Current Biology 12 (21), 1833-1839, 2002 | 162 | 2002 |
Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex ME Witte, PG Nijland, JAR Drexhage, W Gerritsen, D Geerts, ... Acta neuropathologica 125, 231-243, 2013 | 148 | 2013 |
Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex ME Witte, PG Nijland, JAR Drexhage, W Gerritsen, D Geerts, ... Acta neuropathologica 125, 231-243, 2013 | 148 | 2013 |
MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis A Reijerkerk, MA Lopez-Ramirez, B van Het Hof, JAR Drexhage, ... Journal of Neuroscience 33 (16), 6857-6863, 2013 | 146 | 2013 |
Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier R van Doorn, MA Lopes Pinheiro, G Kooij, K Lakeman, B van het Hof, ... Journal of neuroinflammation 9, 1-15, 2012 | 137 | 2012 |
Myc‐associated zinc finger protein (MAZ) is regulated by miR‐125b and mediates VEGF‐induced angiogenesis in glioblastoma M Smits, T Wurdinger, B van het Hof, JAR Drexhage, D Geerts, ... The FASEB Journal 26 (6), 2639-2647, 2012 | 129 | 2012 |
Astrocyte-derived retinoic acid: a novel regulator of blood–brain barrier function in multiple sclerosis MR Mizee, PG Nijland, SMA van der Pol, JAR Drexhage, B van Het Hof, ... Acta neuropathologica 128, 691-703, 2014 | 125 | 2014 |
Fingolimod attenuates ceramide-induced blood–brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes R van Doorn, PG Nijland, N Dekker, ME Witte, MA Lopes-Pinheiro, ... Acta neuropathologica 124, 397-410, 2012 | 120 | 2012 |
Fingolimod attenuates ceramide-induced blood–brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes R van Doorn, PG Nijland, N Dekker, ME Witte, MA Lopes-Pinheiro, ... Acta neuropathologica 124, 397-410, 2012 | 120 | 2012 |
Immunoglobulin A: FcαRI interactions induce neutrophil migration through release of leukotriene B4 L van der Steen, CW Tuk, JE Bakema, G Kooij, A Reijerkerk, G Vidarsson, ... Gastroenterology 137 (6), 2018-2029. e3, 2009 | 117 | 2009 |
SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function RD Fontijn, OL Volger, JO Fledderus, A Reijerkerk, HE de Vries, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (2 …, 2008 | 116 | 2008 |