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Bas van Breukelen
Bas van Breukelen
Associate Professor, Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University
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Highly Robust, Automated, and Sensitive Online TiO2-Based Phosphoproteomics Applied To Study Endogenous Phosphorylation in Drosophila melanogaster
MWH Pinkse, S Mohammed, JW Gouw, B van Breukelen, HR Vos, ...
Journal of proteome research 7 (2), 687-697, 2008
2052008
In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling
PJ Boersema, LY Foong, VMY Ding, S Lemeer, B van Breukelen, R Philp, ...
Molecular & Cellular Proteomics 9 (1), 84-99, 2010
1982010
Profiling of N-acetylated protein termini provides in-depth insights into the N-terminal nature of the proteome
AO Helbig, S Gauci, R Raijmakers, B van Breukelen, M Slijper, ...
Molecular & Cellular Proteomics 9 (5), 928-939, 2010
1492010
Quantitative proteomics and transcriptomics of anaerobic and aerobic yeast cultures reveals post-transcriptional regulation of key cellular processes
MJL de Groot, P Daran-Lapujade, B van Breukelen, TA Knijnenburg, ...
Microbiology 153 (11), 3864-3878, 2007
1412007
Current challenges in software solutions for mass spectrometry-based quantitative proteomics
S Cappadona, PR Baker, PR Cutillas, AJR Heck, B van Breukelen
Amino acids 43, 1087-1108, 2012
1392012
Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and …
A Scholten, MK Poh, TAB van Veen, B van Breukelen, MA Vos, AJR Heck
Journal of proteome research 5 (6), 1435-1447, 2006
1322006
Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis
TY Low, S van Heesch, H van den Toorn, P Giansanti, A Cristobal, ...
Cell reports 5 (5), 1469-1478, 2013
1302013
The PRoteomics IDEntification (PRIDE) Converter 2 framework: an improved suite of tools to facilitate data submission to the PRIDE database and the ProteomeXchange consortium
RG Côté, J Griss, JA Dianes, R Wang, JC Wright, HWP van den Toorn, ...
Molecular & Cellular Proteomics 11 (12), 1682-1689, 2012
1102012
Targeted analysis of protein termini
W Dormeyer, S Mohammed, B Breukelen, J Krijgsveld, AJR Heck
Journal of proteome research 6 (12), 4634-4645, 2007
1102007
An augmented multiple-protease-based human phosphopeptide atlas
P Giansanti, TT Aye, H van den Toorn, M Peng, B van Breukelen, ...
Cell reports 11 (11), 1834-1843, 2015
1042015
Protease bias in absolute protein quantitation
M Peng, N Taouatas, S Cappadona, B Van Breukelen, S Mohammed, ...
Nature methods 9 (6), 524-525, 2012
1012012
Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra
EL de Graaf, AFM Altelaar, B van Breukelen, S Mohammed, AJR Heck
Journal of proteome research 10 (9), 4334-4341, 2011
1012011
Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels
AO Helbig, S Rosati, PWWM Pijnappel, B van Breukelen, MHTH Timmers, ...
BMC genomics 11, 1-15, 2010
1012010
The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication
TH Stracker, GD Cassell, P Ward, YM Loo, B Van Breukelen, ...
Journal of virology 78 (1), 441-453, 2004
1012004
Daily rhythms in the cyanobacterium Synechococcus elongatus probed by high-resolution mass spectrometry–based proteomics reveals a small defined set of cyclic proteins
ACL Guerreiro, M Benevento, R Lehmann, B van Breukelen, H Post, ...
Molecular & cellular proteomics 13 (8), 2042-2055, 2014
882014
Comparative phosphoproteomics reveals evolutionary and functional conservation of phosphorylation across eukaryotes
J Boekhorst, B van Breukelen, AJR Heck, B Snel
Genome biology 9, 1-9, 2008
882008
Online Automated in Vivo Zebrafish Phosphoproteomics: From Large-Scale Analysis Down to a Single Embryo
S Lemeer, MWH Pinkse, S Mohammed, B van Breukelen, J den Hertog, ...
Journal of proteome research 7 (4), 1555-1564, 2008
862008
Facilitating protein disulfide mapping by a combination of pepsin digestion, electron transfer higher energy dissociation (EThcD), and a dedicated search algorithm SlinkS
F Liu, B van Breukelen, AJR Heck
Molecular & Cellular Proteomics 13 (10), 2776-2786, 2014
852014
ROCK 1 is a potential combinatorial drug target for BRAF mutant melanoma
MA Smit, G Maddalo, K Greig, LM Raaijmakers, PA Possik, ...
Molecular systems biology 10 (12), 772, 2014
622014
A versatile peptide pI calculator for phosphorylated and N‐terminal acetylated peptides experimentally tested using peptide isoelectric focusing
S Gauci, B Van Breukelen, SM Lemeer, J Krijgsveld, AJR Heck
Proteomics 8 (23‐24), 4898-4906, 2008
612008
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Artikelen 1–20