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Ghader Bashiri
Ghader Bashiri
School of Biological Sciences, The University of Auckland
Geverifieerd e-mailadres voor auckland.ac.nz
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Metabolic Engineering of Cofactor F420 Production in Mycobacterium smegmatis
G Bashiri, AM Rehan, DR Greenwood, JMJ Dickson, EN Baker
PloS one 5 (12), e15803, 2010
1432010
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of …
G Bashiri, CJ Squire, NJ Moreland, EN Baker
Journal of Biological Chemistry 283 (25), 17531-17541, 2008
1072008
Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis
P Wang, G Bashiri, X Gao, MR Sawaya, Y Tang
Journal of the American Chemical Society 135 (19), 7138-7141, 2013
972013
Functional Genome Mining Reveals a Class V Lanthipeptide Containing a d‐Amino Acid Introduced by an F420H2‐Dependent Reductase
M Xu, F Zhang, Z Cheng, G Bashiri, J Wang, J Hong, Y Wang, L Xu, ...
Angewandte Chemie International Edition 59 (41), 18029-18035, 2020
912020
A new Gateway® vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis
RM Goldstone, NJ Moreland, G Bashiri, EN Baker, JS Lott
Protein expression and purification 57 (1), 81-87, 2008
672008
Mutations in fbiD (Rv2983) as a Novel Determinant of Resistance to Pretomanid and Delamanid in Mycobacterium tuberculosis
D Rifat, SY Li, T Ioerger, K Shah, JP Lanoix, J Lee, G Bashiri, J Sacchettini, ...
Antimicrobial agents and chemotherapy 65 (1), 10.1128/aac. 01948-20, 2020
642020
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system
G Bashiri, CJ Squire, EN Baker, NJ Moreland
Protein expression and purification 54 (1), 38-44, 2007
632007
Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies
G Bashiri, EN Baker
Protein science 24 (1), 1-10, 2015
612015
A revised biosynthetic pathway for the cofactor F420 in prokaryotes
G Bashiri, J Antoney, ENM Jirgis, MV Shah, B Ney, J Copp, SM Stuteley, ...
Nature communications 10 (1), 1558, 2019
592019
Targeting isocitrate lyase for the treatment of latent tuberculosis
RP Bhusal, G Bashiri, BXC Kwai, J Sperry, IKH Leung
Drug discovery today 22 (7), 1008-1016, 2017
502017
A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography
RD Bunker, K Mandal, G Bashiri, JJ Chaston, BL Pentelute, JS Lott, ...
Proceedings of the National Academy of Sciences 112 (14), 4310-4315, 2015
472015
Regulation and quality control of adiponectin assembly by endoplasmic reticulum chaperone ERp44
L Hampe, M Radjainia, C Xu, PWR Harris, G Bashiri, DC Goldstone, ...
Journal of Biological Chemistry 290 (29), 18111-18123, 2015
432015
A NADH-accepting imine reductase variant: immobilization and cofactor regeneration by oxidative deamination
M Gand, C Thöle, H Müller, H Brundiek, G Bashiri, M Höhne
Journal of biotechnology 230, 11-18, 2016
422016
β-NAD as a building block in natural product biosynthesis
L Barra, T Awakawa, K Shirai, Z Hu, G Bashiri, I Abe
Nature 600 (7890), 754-758, 2021
392021
Itaconate is a covalent inhibitor of the Mycobacterium tuberculosis isocitrate lyase
BXC Kwai, AJ Collins, MJ Middleditch, J Sperry, G Bashiri, IKH Leung
RSC Medicinal Chemistry 12 (1), 57-61, 2021
392021
Biosynthesis of the Thiopeptins and Identification of an F420H2-Dependent Dehydropiperidine Reductase
H Ichikawa, G Bashiri, WL Kelly
Journal of the American Chemical Society 140 (34), 10749-10756, 2018
372018
Tat–Dependent Translocation of an F420–Binding Protein of Mycobacterium tuberculosis
G Bashiri, EF Perkowski, AP Turner, ME Feltcher, M Braunstein, EN Baker
Public Library of Science 7 (10), e45003, 2012
342012
Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2
RP Bhusal, W Jiao, BXC Kwai, J Reynisson, AJ Collins, J Sperry, ...
Nature Communications 10 (1), 4639, 2019
302019
Comparative bioactivation of the novel anti‐tuberculosis agent PA‐824 in Mycobacteria and a subcellular fraction of human liver
M Dogra, BD Palmer, G Bashiri, MD Tingle, SS Shinde, RF Anderson, ...
British journal of pharmacology 162 (1), 226-236, 2011
302011
Structural views along the Mycobacterium tuberculosis MenD reaction pathway illuminate key aspects of thiamin diphosphate-dependent enzyme mechanisms
ENM Jirgis, G Bashiri, EMM Bulloch, JM Johnston, EN Baker
Structure 24 (7), 1167-1177, 2016
292016
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