|Clearance of p16 Ink4a-positive senescent cells delays ageing-associated disorders|
DJ Baker, T Wijshake, T Tchkonia, NK LeBrasseur, BG Childs, ...
Nature 479 (7372), 232-236, 2011
|AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis|
T Okuda, J Van Deursen, SW Hiebert, G Grosveld, JR Downing
Cell 84 (2), 321-330, 1996
|Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4|
HU Wang, ZF Chen, DJ Anderson
Cell 93 (5), 741-753, 1998
|Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene|
K Shimoda, J van Deursent, MY Sangster, SR Sarawar, RT Carson, ...
Nature 380 (6575), 630-633, 1996
|Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses|
S Teglund, C McKay, E Schuetz, JM Van Deursen, D Stravopodis, ...
Cell 93 (5), 841-850, 1998
|Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells|
WE Thierfelder, JM van Deursen, K Yamamoto, RA Tripp, SR Sarawar, ...
Nature 382 (6587), 171-174, 1996
|Jak2 is essential for signaling through a variety of cytokine receptors|
E Parganas, D Wang, D Stravopodis, DJ Topham, JC Marine, S Teglund, ...
Cell 93 (3), 385-395, 1998
|Naturally occurring p16Ink4a-positive cells shorten healthy lifespan|
DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong, ...
Nature 530 (7589), 184-189, 2016
|The role of senescent cells in ageing|
JM Van Deursen
Nature 509 (7501), 439-446, 2014
|Cellular senescence and the senescent secretory phenotype: therapeutic opportunities|
T Tchkonia, Y Zhu, J Van Deursen, J Campisi, JL Kirkland
The Journal of clinical investigation 123 (3), 966-972, 2013
|Cellular senescence in aging and age-related disease: from mechanisms to therapy|
BG Childs, M Durik, DJ Baker, JM Van Deursen
Nature medicine 21 (12), 1424-1435, 2015
|BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice|
DJ Baker, KB Jeganathan, JD Cameron, M Thompson, S Juneja, ...
Nature genetics 36 (7), 744-749, 2004
|Defective lymphoid development in mice lacking Jak3|
T Nosaka, JMA Van Deursen, RA Tripp, WE Thierfelder, BA Witthuhn, ...
Science 270 (5237), 800-802, 1995
|MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals|
Z Lou, K Minter-Dykhouse, S Franco, M Gostissa, MA Rivera, A Celeste, ...
Molecular cell 21 (2), 187-200, 2006
|Fat tissue, aging, and cellular senescence|
T Tchkonia, DE Morbeck, T Von Zglinicki, J Van Deursen, J Lustgarten, ...
Aging cell 9 (5), 667-684, 2010
|Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells|
R Moriggl, DJ Topham, S Teglund, V Sexl, C McKay, D Wang, ...
Immunity 10 (2), 249-259, 1999
|Regulation of the T-independent humoral response by TACI|
GU von Bülow, JM van Deursen, RJ Bram
Immunity 14 (5), 573-582, 2001
|Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation|
H Huang, KM Regan, F Wang, D Wang, DI Smith, JMA Van Deursen, ...
Proceedings of the National Academy of Sciences 102 (5), 1649-1654, 2005
|The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88|
M Fornerod, J Van Deursen, S Van Baal, A Reynolds, D Davis, KG Murti, ...
The EMBO journal 16 (4), 807-816, 1997
|Expression of a Knocked-In AML1-ETO Leukemia Gene Inhibits the Establishment of Normal Definitive Hematopoiesis and Directly Generates Dysplastic …|
T Okuda, Z Cai, S Yang, N Lenny, C Lyu, JMA van Deursen, H Harada, ...
Blood, The Journal of the American Society of Hematology 91 (9), 3134-3143, 1998