Neil Osheroff
Neil Osheroff
Professor of Biochemistry, Vanderbilt University School of Medicine
Verified email at Vanderbilt.Edu
Title
Cited by
Cited by
Year
Mechanism of quinolone action and resistance
KJ Aldred, RJ Kerns, N Osheroff
Biochemistry 53 (10), 1565-1574, 2014
7172014
Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme
DA Burden, N Osheroff
Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1400 (1-3 …, 1998
6961998
Topoisomerase Poisons: Harnessing the Dark Side of Enzyme Mechanism (∗)
SJ Froelich-Ammon, N Osheroff
Journal of Biological Chemistry 270 (37), 21429-21432, 1995
6611995
In situ localization of DNA topoisomerase II, a major polypeptide component of the Drosophila nuclear matrix fraction
M Berrios, N Osheroff, PA Fisher
Proceedings of the National Academy of Sciences 82 (12), 4142-4146, 1985
5881985
Etoposide, topoisomerase II and cancer
EL Baldwin, N Osheroff
Current Medicinal Chemistry-Anti-Cancer Agents 5 (4), 363-372, 2005
4912005
Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice
JM Fortune, N Osheroff
Academic Press 64, 221-253, 2000
4572000
DNA topoisomerase II, genotoxicity, and cancer
AK McClendon, N Osheroff
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 623 (1 …, 2007
3902007
The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing
JE Deweese, N Osheroff
Nucleic acids research 37 (3), 738-748, 2009
3862009
DNA topoisomerase II from Drosophila melanogaster. Relaxation of supercoiled DNA.
N Osheroff, ER Shelton, DL Brutlag
Journal of Biological Chemistry 258 (15), 9536-9543, 1983
3521983
Biochemical basis for the interactions of type I and type II topoisomerases with DNA
N Osheroff
Pharmacology & therapeutics 41 (1-2), 223-241, 1989
3491989
Catalytic function of DNA topoisomerase II
N Osheroff, EL Zechiedrich, KC Gale
BioEssays 13 (6), 269-275, 1991
3001991
DNA topoisomerase II in therapy-related acute promyelocytic leukemia
AR Mistry, CA Felix, RJ Whitmarsh, A Mason, A Reiter, B Cassinat, ...
New England Journal of Medicine 352 (15), 1529-1538, 2005
2872005
Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide
N Osheroff
Biochemistry 28 (15), 6157-6160, 1989
2841989
Merbarone inhibits the catalytic activity of human topoisomerase IIα by blocking DNA cleavage
JM Fortune, N Osheroff
Journal of Biological Chemistry 273 (28), 17643-17650, 1998
2781998
Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase II activity in vitro
P Ackerman, CV Glover, N Osheroff
Proceedings of the National Academy of Sciences 82 (10), 3164-3168, 1985
2781985
When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs
AH Corbett, N Osheroff
Chemical Research in Toxicology 6 (5), 585-597, 1993
2751993
Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers.
EL Zechiedrich, N Osheroff
The EMBO journal 9 (13), 4555-4562, 1990
2621990
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
N Osheroff
Journal of Biological Chemistry 261 (21), 9944-9950, 1986
2441986
Stabilization of eukaryotic topoisomerase II-DNA cleavage complexes
AM Wilstermann, N Osheroff
Current topics in medicinal chemistry 3 (3), 321-338, 2003
2112003
Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage
MJ Robinson, BA Martin, TD Gootz, PR McGuirk, M Moynihan, JA Sutcliffe, ...
Journal of Biological Chemistry 266 (22), 14585-14592, 1991
1911991
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