| Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells IMN Wortel, LT van der Meer, MS Kilberg, FN van Leeuwen Trends in Endocrinology & Metabolism, 2017 | 437 | 2017 |
| Gfi1 and Gfi1b: key regulators of hematopoiesis LT Van der Meer, JH Jansen, BA Van Der Reijden Leukemia 24 (11), 1834-1843, 2010 | 226 | 2010 |
| The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution E Waanders, B Scheijen, LT van der Meer, SV van Reijmersdal, ... PLoS genetics 8 (2), e1002533, 2012 | 113 | 2012 |
| Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients B Scheijen, JM Boer, E Tijchon, D van Ingen Schenau, L van Emst, ... haematologica, haematol. 2016.153023, 2016 | 56 | 2016 |
| The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains JA Marteijn, LT Van Der Meer, JJ Smit, SM Noordermeer, W Wissink, ... Leukemia 23 (8), 1480-1489, 2009 | 40 | 2009 |
| Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1 JAF Marteijn, LT van der Meer, L van Emst, S van Reijmersdal, W Wissink, ... Blood 110 (9), 3128-3135, 2007 | 34 | 2007 |
| Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress L Yuniati, LT van der Meer, E Tijchon, D van Ingen Schenau, L van Emst, ... Oncotarget 7 (3), 3128, 2016 | 33 | 2016 |
| Diminished proteasomal degradation results in accumulation of Gfi1 protein in monocytes JAF Marteijn, LT van der Meer, L Van Emst, T de Witte, JH Jansen, ... Blood 109 (1), 100-108, 2007 | 26 | 2007 |
| In Vivo Imaging of Antileukemic Drug Asparaginase Reveals a Rapid Macrophage-Mediated Clearance from the Bone Marrow LT van der Meer, SYA Terry, DS van Ingen Schenau, KC Andree, ... Journal of Nuclear Medicine 58 (2), 214-220, 2017 | 22 | 2017 |
| A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics LT van der Meer, E Waanders, M Levers, H Venselaar, D Roeleveld, ... Blood 124 (19), 3027-3029, 2014 | 17 | 2014 |
| Tumor Suppressors BTG1 and IKZF1 Cooperate during Mouse Leukemia Development and Impact Relapse Rate in Childhood Acute Lymphoblastic Leukemia B Scheijen, E Tijchon, D van Ingen Schenau, R Marke, L van Emst, ... Blood 126 (23), 905-905, 2015 | 3 | 2015 |
| A CRISPR/Cas9 Based Kinome Screen Identifies Bruton Tyrosine Kinase (BTK) As an Important Determinant of Asparaginase Treatment Response in Acute Lymphoblastic Leukemia M Butler, L Van Der Meer, J Yu, S Jenni, MP Dobay, P Hoogerbrugge, ... Blood 130 (Suppl 1), 34-34, 2017 | 2 | 2017 |
| CRISPR/CAS9 Based Reverse Genetics Identifies Therapeutic Targets to Improve Therapy Response in Paediatric Acute Lymphoblastic Leukemia M Butler, L van der Meer, J Yu, T Beeby, R Kuiper, F van Leeuwen PEDIATRIC BLOOD & CANCER 64, S5-S6, 2017 | 2 | 2017 |
| Crispr/Cas9 Based Kinome Screen Identifies Novel Targets That Determine Sensitivity for Asparaginase Therapy in Acute Lymphoblastic Leukemia LT Van Der Meer, J Yu, M Butler, JMR van der Meer, RP Kuiper, ... Blood 126 (23), 2629-2629, 2015 | 1 | 2015 |
| The Therapeutic Protein Asparaginase Is Efficiently Cleared By Bone Barrow and Spleen Resident Macrophages LT van der Meer, SYA Terry, DS van IngenSchenau, KC Andree, ... Blood 124 (21), 3630-3630, 2014 | 1 | 2014 |
| Focal BTG1 Deletions Occur in Specific Precursor B-Cell Acute Lymphoblastic Leukemia Subtypes At Defined Hotspots Due to Aberrant V(D)J Recombination B Scheijen, E Waanders, SV van Reijmersdal, LT van der Meer, ... Blood 118 (21), 399-399, 2011 | 1 | 2011 |
| A Key Role for Tumor Suppressor BTG1 In the Regulation of Metabolic Stress Responses: Implications for Asparaginase Resistance In Pediatric Acute Lymphoblastic Leukemia. L van der Meer, M Levers, L van Emst, JC van Galen, AG van Kessel, ... Blood 116 (21), 1028-1028, 2010 | 1 | 2010 |
| Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase LT Van Der Meer, SYA Terry, D van Ingen Schenau, K Andree, ... Blood 126 (23), 3768-3768, 2015 | | 2015 |
| Tumor Suppressor Genes Ikzf1 And Btg1 Cooperate In Acute Lymphoblastic Leukemia Development And Glucocorticoid Therapy Resistance R Marke, E Tijchon, D van Ingen Schenau, J Boer, M Demkes, L van Emst, ... Pediatric Blood & Cancer 62, S153, 2015 | | 2015 |
| Btg1-Deficiency Promotes ETV6-RUNX1-Mediated Leukemic Transformation By Upregulation of BCL6 E Tijchon, L van Emst, D van Ingen Schenau, LT van der Meer, S de Rijk, ... Blood 124 (21), 5193-5193, 2014 | | 2014 |
