Laurens van der Meer
Laurens van der Meer
Assistant Professor Pediatric Oncology, Radboudu university medical center
Verified email at radboudumc.nl
Title
Cited by
Cited by
Year
Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells
IMN Wortel, LT van der Meer, MS Kilberg, FN van Leeuwen
Trends in Endocrinology & Metabolism, 2017
1812017
Gfi1 and Gfi1b: key regulators of hematopoiesis
LT Van der Meer, JH Jansen, BA Van Der Reijden
Leukemia 24 (11), 1834-1843, 2010
1752010
The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution
E Waanders, B Scheijen, LT van der Meer, SV van Reijmersdal, ...
PLoS genetics 8 (2), e1002533, 2012
1092012
Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients
B Scheijen, JM Boer, E Tijchon, D van Ingen Schenau, L van Emst, ...
haematologica, haematol. 2016.153023, 2016
392016
The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains
JA Marteijn, LT Van Der Meer, JJ Smit, SM Noordermeer, W Wissink, ...
Leukemia 23 (8), 1480-1489, 2009
322009
Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1
JAF Marteijn, LT van der Meer, L van Emst, S van Reijmersdal, W Wissink, ...
Blood 110 (9), 3128-3135, 2007
292007
Diminished proteasomal degradation results in accumulation of Gfi1 protein in monocytes
JAF Marteijn, LT van der Meer, L Van Emst, T de Witte, JH Jansen, ...
Blood 109 (1), 100-108, 2007
252007
Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress
L Yuniati, LT van der Meer, E Tijchon, D van Ingen Schenau, L van Emst, ...
Oncotarget 7 (3), 3128, 2016
172016
In Vivo Imaging of Antileukemic Drug Asparaginase Reveals a Rapid Macrophage-Mediated Clearance from the Bone Marrow
LT van der Meer, SYA Terry, DS van Ingen Schenau, KC Andree, ...
Journal of Nuclear Medicine 58 (2), 214-220, 2017
152017
A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics
LT van der Meer, E Waanders, M Levers, H Venselaar, D Roeleveld, ...
Blood 124 (19), 3027-3029, 2014
132014
Tumor Suppressors BTG1 and IKZF1 Cooperate during Mouse Leukemia Development and Impact Relapse Rate in Childhood Acute Lymphoblastic Leukemia
B Scheijen, E Tijchon, D van Ingen Schenau, R Marke, L van Emst, ...
Blood 126 (23), 905-905, 2015
32015
A CRISPR/Cas9 Based Kinome Screen Identifies Bruton Tyrosine Kinase (BTK) As an Important Determinant of Asparaginase Treatment Response in Acute Lymphoblastic Leukemia
M Butler, L Van Der Meer, J Yu, S Jenni, MP Dobay, P Hoogerbrugge, ...
Blood 130 (Suppl 1), 34-34, 2017
22017
CRISPR/CAS9 Based Reverse Genetics Identifies Therapeutic Targets to Improve Therapy Response in Paediatric Acute Lymphoblastic Leukemia
M Butler, L van der Meer, J Yu, T Beeby, R Kuiper, F van Leeuwen
PEDIATRIC BLOOD & CANCER 64, S5-S6, 2017
22017
Crispr/Cas9 Based Kinome Screen Identifies Novel Targets That Determine Sensitivity for Asparaginase Therapy in Acute Lymphoblastic Leukemia
LT Van Der Meer, J Yu, M Butler, JMR van der Meer, RP Kuiper, ...
Blood 126 (23), 2629-2629, 2015
12015
The Therapeutic Protein Asparaginase Is Efficiently Cleared By Bone Barrow and Spleen Resident Macrophages
LT van der Meer, SYA Terry, DS van IngenSchenau, KC Andree, ...
Blood 124 (21), 3630-3630, 2014
12014
Diminished Asparaginase Clearance Due To A Mutation In Cathepsin B
L van der Meer, M Levers, E Waanders, H Venselaar, P Hoogerbrugge, ...
Pediatric Blood & Cancer 59 (6), 1034, 2012
12012
A Key Role for Tumor Suppressor BTG1 In the Regulation of Metabolic Stress Responses: Implications for Asparaginase Resistance In Pediatric Acute Lymphoblastic Leukemia.
L van der Meer, M Levers, L van Emst, JC van Galen, AG van Kessel, ...
Blood 116 (21), 1028-1028, 2010
12010
Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase
LT Van Der Meer, SYA Terry, D van Ingen Schenau, K Andree, ...
Blood 126 (23), 3768-3768, 2015
2015
Tumor Suppressor Genes Ikzf1 And Btg1 Cooperate In Acute Lymphoblastic Leukemia Development And Glucocorticoid Therapy Resistance
R Marke, E Tijchon, D van Ingen Schenau, J Boer, M Demkes, L van Emst, ...
Pediatric Blood & Cancer 62, S153, 2015
2015
Btg1-Deficiency Promotes ETV6-RUNX1-Mediated Leukemic Transformation By Upregulation of BCL6
E Tijchon, L van Emst, D van Ingen Schenau, LT van der Meer, S de Rijk, ...
Blood 124 (21), 5193-5193, 2014
2014
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