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Jan-Renier Moonen
Jan-Renier Moonen
Scientific Director, Precision Medicine Immunology @AbbVie
Verified email at abbvie.com
Title
Cited by
Cited by
Year
Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress
JRAJ Moonen, ES Lee, M Schmidt, M Maleszewska, JA Koerts, ...
Cardiovascular research 108 (3), 377-386, 2015
2362015
IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner
M Maleszewska, JRAJ Moonen, N Huijkman, B van de Sluis, G Krenning, ...
Immunobiology 218 (4), 443-454, 2013
2172013
In pulmonary arterial hypertension, reduced BMPR2 promotes endothelial-to-mesenchymal transition via HMGA1 and its target slug
RK Hopper, JRAJ Moonen, I Diebold, A Cao, CJ Rhodes, NF Tojais, ...
Circulation 133 (18), 1783-1794, 2016
2142016
Endothelial progenitor cells give rise to pro-angiogenic smooth muscle-like progeny
JRAJ Moonen, G Krenning, MGL Brinker, JA Koerts, MJA Van Luyn, ...
Cardiovascular research 86 (3), 506-515, 2010
1792010
FGF2 inhibits endothelial–mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-β signaling
ACP Correia, JRAJ Moonen, MGL Brinker, G Krenning
Journal of cell science 129 (3), 569-579, 2016
1132016
Vascular smooth muscle cells for use in vascular tissue engineering obtained by endothelial-to-mesenchymal transdifferentiation (EnMT) on collagen matrices
G Krenning, JRAJ Moonen, MJA van Luyn, MC Harmsen
Biomaterials 29 (27), 3703-3711, 2008
1132008
Intrinsic endocardial defects contribute to hypoplastic left heart syndrome
Y Miao, L Tian, M Martin, SL Paige, FX Galdos, J Li, A Klein, H Zhang, ...
Cell stem cell 27 (4), 574-589. e8, 2020
1112020
Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus
JRAJ Moonen, K de Leeuw, XJGY van Seijen, CGM Kallenberg, ...
Arthritis research & therapy 9 (4), R84, 2007
972007
Cellular senescence impairs the reversibility of pulmonary arterial hypertension
DE Van Der Feen, GPL Bossers, QAJ Hagdorn, JR Moonen, K Kurakula, ...
Science Translational Medicine 12 (554), eaaw4974, 2020
802020
Endothelial plasticity: shifting phenotypes through force feedback
G Krenning, VG Barauna, JE Krieger, MC Harmsen, JRAJ Moonen
Stem cells international 2016, 2016
802016
Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy
N Sayed, C Liu, M Ameen, F Himmati, JZ Zhang, S Khanamiri, JR Moonen, ...
Science translational medicine 12 (554), eaax9276, 2020
592020
Erk5 inhibits endothelial migration via KLF2-dependent down-regulation of PAK1
RK Komaravolu, C Adam, JRAJ Moonen, MC Harmsen, M Goebeler, ...
Cardiovascular research 105 (1), 86-95, 2015
572015
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension
T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ...
Circulation 136 (20), 1920-1935, 2017
542017
The flow dependency of Tie2 expression in endotoxemia
NF Kurniati, RM Jongman, F Vom Hagen, KC Spokes, J Moser, ER Regan, ...
Intensive care medicine 39, 1262-1271, 2013
542013
PPARγ-p53-mediated vasculoregenerative program to reverse pulmonary hypertension
JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ...
Circulation research 128 (3), 401-418, 2021
432021
ALDH1A3 coordinates metabolism with gene regulation in pulmonary arterial hypertension
D Li, NY Shao, JR Moonen, Z Zhao, M Shi, S Otsuki, L Wang, T Nguyen, ...
Circulation 143 (21), 2074-2090, 2021
422021
Pleiotropism of adiponectin: inflammation, neovascularization, and fibrosis
G Krenning, JRAJ Moonen, MC Harmsen
Circulation research 104 (9), 1029-1031, 2009
372009
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress
JR Moonen, J Chappell, M Shi, T Shinohara, D Li, MR Mumbach, F Zhang, ...
Nature communications 13 (1), 4941, 2022
352022
Generating new blood flow: integrating developmental biology and tissue engineering
G Krenning, JRAJ Moonen, MJA van Luyn, MC Harmsen
Trends in cardiovascular medicine 18 (8), 312-323, 2008
352008
MicroRNA‐374b induces endothelial‐to‐mesenchymal transition and early lesion formation through the inhibition of MAPK7 signaling
B Vanchin, E Offringa, J Friedrich, MGL Brinker, B Kiers, AC Pereira, ...
The Journal of pathology 247 (4), 456-470, 2019
292019
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