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Joao Fadista
Joao Fadista
Principal Scientist, Novo Nordisk (Denmark)
Geverifieerd e-mailadres voor ssi.dk
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Analyses of pig genomes provide insight into porcine demography and evolution
MAM Groenen, AL Archibald, H Uenishi, CK Tuggle, Y Takeuchi, ...
Nature 491 (7424), 393-398, 2012
14712012
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
12392016
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
J Fadista, P Vikman, EO Laakso, IG Mollet, JL Esguerra, J Taneera, ...
Proceedings of the National Academy of Sciences 111 (38), 13924-13929, 2014
4702014
Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes
E Nilsson, PA Jansson, A Perfilyev, P Volkov, M Pedersen, MK Svensson, ...
Diabetes 63 (9), 2962-2976, 2014
4172014
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ...
Nature genetics 47 (12), 1415-1425, 2015
4112015
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
J Taneera, S Lang, A Sharma, J Fadista, Y Zhou, E Ahlqvist, A Jonsson, ...
Cell metabolism 16 (1), 122-134, 2012
4082012
The (in) famous GWAS P-value threshold revisited and updated for low-frequency variants
J Fadista, AK Manning, JC Florez, L Groop
European Journal of Human Genetics 24 (8), 1202-1205, 2016
3552016
Increased melatonin signaling is a risk factor for type 2 diabetes
T Tuomi, CLF Nagorny, P Singh, H Bennet, Q Yu, I Alenkvist, B Isomaa, ...
Cell metabolism 23 (6), 1067-1077, 2016
2472016
TCF7L2 is a master regulator of insulin production and processing
Y Zhou, SY Park, J Su, K Bailey, E Ottosson-Laakso, L Shcherbina, ...
Human molecular genetics 23 (24), 6419-6431, 2014
2362014
The diabetes susceptibility gene Clec16a regulates mitophagy
SA Soleimanpour, A Gupta, M Bakay, AM Ferrari, DN Groff, J Fadista, ...
Cell 157 (7), 1577-1590, 2014
1982014
Copy number variation in the bovine genome
J Fadista, B Thomsen, LE Holm, C Bendixen
BMC genomics 11, 1-12, 2010
1982010
A Central Role for GRB10 in Regulation of Islet Function in Man
I Prokopenko, W Poon, R Maegi, R Prasad B, SA Salehi, P Almgren, ...
PLoS genetics 10 (4), e1004235, 2014
1842014
A snapshot of CNVs in the pig genome
J Fadista, M Nygaard, LE Holm, B Thomsen, C Bendixen
PloS one 3 (12), e3916, 2008
1502008
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms
M Claussnitzer, SN Dankel, B Klocke, H Grallert, V Glunk, T Berulava, ...
Cell 156 (1), 343-358, 2014
1452014
Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women
V Steinthorsdottir, R McGinnis, NO Williams, L Stefansdottir, ...
Nature Communications 11 (1), 5976, 2020
1442020
The genetic landscape of renal complications in type 1 diabetes
N Sandholm, N Van Zuydam, E Ahlqvist, T Juliusdottir, HA Deshmukh, ...
Journal of the American Society of Nephrology 28 (2), 557-574, 2017
1252017
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
V Lagou, R Mägi, JJ Hottenga, H Grallert, JRB Perry, N Bouatia-Naji, ...
Nature communications 12 (1), 24, 2021
1152021
Global assessment of genomic variation in cattle by genome resequencing and high-throughput genotyping
B Zhan, J Fadista, B Thomsen, J Hedegaard, F Panitz, C Bendixen
BMC genomics 12, 1-20, 2011
1152011
LoFtool: a gene intolerance score based on loss-of-function variants in 60 706 individuals
J Fadista, N Oskolkov, O Hansson, L Groop
Bioinformatics 33 (4), 471-474, 2017
1122017
Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia
J Taneera, J Fadista, E Ahlqvist, D Atac, E Ottosson-Laakso, CB Wollheim, ...
Human molecular genetics 24 (7), 1945-1955, 2015
1072015
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